A framework for the systematic realisation of phenomena for enhanced sensing of radiological and nuclear materials, and radiation

The quest for new sensing phenomena continues because detecting, discriminating, identifying, measuring and monitoring nuclear materials and their radiation from greater range, at lower concentrations, and in a more timely fashion brings greater safety, security and efficiency. The potential phenomena are diverse, and those that have been realised can be found in disparate fields of science, engineering and medicine, which makes the full range difficult to realise and record. The framework presented here offers a means to systematically and comprehensively explore nuclear sensing phenomena. The approach is based on the fundamental concepts of matter and energy, where the sequence starts with the original nuclear material and its emissions, and progressively considers signatures arising from secondary effects and the emissions from associated materials and the environment. Concepts of operations such as active and passive interrogation, and networked sensing are considered. In this operational light, unpacking nuclear signatures forces a fresh look at the sensing concept. It also exposes how some phenomena that exist in established technology may be considered novel based on how they could be exploited rather than what they fundamentally are. This article selects phenomena purely to illustrate the framework and how it can be best used to foster creativity in the quest for novel phenomena rather than exhaustively listing, categorising or comparing any practical aspects of candidate phenomena

Rapid prototyping-coded masks for x-ray backscatter imaging

Coded masks (CM) often lack a self-supporting structure that is difficult to manufacture without recourse to drilled holes in place of ideal square apertures, degrading imaging properties. An alternative approach is presented with three-dimensional (3-D) printed CM molds cast with a radio-opaque material that allows square elements to be retained. Two methods are presented; hot casting a bismuth alloy (density 8.6  g cm  −  3) and cold casting with tungsten powder/epoxy resin (densities 9.6 and 10.6  g cm  −  3). A critical review of 3-D printed-CM fabrication along with some typical x-ray backscatter images is presented. A signal-to-noise ratio from both the machined tungsten and cold cast 3-D printed mask were comparable, with the former having a slight advantage. Also, 3-D printed cold cast masks were found to be more economical and easier to rapid prototype over traditional drilled tungsten masks

An artificial X-ray wire test emitter and calculations on the resolution and field of view of X-ray pinhole optics by simulation

The PENELOPE Monte Carlo simulation code was used to evaluate pinhole mask parameters for X-ray backscatter imaging in a security application. This work makes four major contributions: it describes a convenient efficient test object for evaluating X-ray optics, it converts the PENELOPE output into a simulated CCD image, it compactly outlines how image characteristics can be simply and reproducibly quantified, and it gives guidance on suitable materials and geometries for pinhole masks for X-ray imaging that could be applied to more complicated X-ray optics, such as coded masks. A novel test object X-ray emitter with the shape of a thin wire was specifically designed to explore the effect of mask material thickness and pinhole aperture diameter on image quality. Setting the test object to be the X-ray emitter rather than being a passive scatterer increases computational speed. The photon energy distribution of the artificial test object was set flat between selected energy limits to avoid the model being specific to any particular X-ray source technology. The modelled detector is an array of 1040 x 1392 pixels’ area detector inside a lead-lined camera housing. The pixelated detector was modelled by digitising the surface area represented by the PENELOPE phase space file and integrating the energies of the photons impacting each pixel with MATLAB code. The pinhole must be wide enough for sufficient field of view, whilst narrow enough for sufficient spatial resolution and the mask material needs to be thick enough to absorb most X-rays. When the mask material was too thick and the aperture too narrow, a collimation effect occurred. The consequence of excess collimation in a coded aperture is partial coding giving poor image reconstruction. Pure tungsten appears the most versatile material tested, where a 2 mm thickness and 2 mm aperture gives the most appropriate image characteristics for X-ray security imaging

Investigating electric field induced molecular distortions in polypropylene using Raman spectroscopy

Polymeric electric insulators are an integral part of many electronic circuits and systems. Changes induced by an electric field can affect various mechanisms; including electrical polarisation and electromechanical properties. Changes in the dielectric material can be tracked using spectroscopic methods. This study has shown that analysing polypropylene under electric field stress using Raman spectroscopy in combination with principal component analysis allows small changes in the non-crystalline phase to be identified. We have observed that for polypropylene, vibrational motion and changes in conformation occur mostly within the tie molecules connecting the overall cluster network. Amorphous molecular chains in the spherulites were also found to orient and form into a smectic mesophase. These electromechanical changes at the micro- and macromolecular level were found to be generally reversible once the stress is removed. However, with increased aging, these changes may lead to adverse structural changes and thus, in the future, this information may be used to inform faults and defect detection within polymeric dielectric materials

Low open fraction coded masks for x-ray backscatter imaging

Previous research has indicated that coded masks with open fractions <0.5 are optimal for imaging some types of far-field scenes. The open fraction, in this case, refers to the ratio of open elements in the mask, with values <0.5 considered as low open fraction. Research is limited by the sparsity of <0.5 open fractions masks; thus a further 94 lower open fraction arrays are calculated and presented. These include the dilute uniformly redundant array and singer set, along with information on imaging potential, array sizes, and open fractions. Signal-to-noise ratio reveals the 0.5 open fraction modified uniformly redundant array to be the optimal coded mask for near-field x-ray backscatter imaging, over the lower open fraction singer set, dilute uniformly redundant and random arra

Potential contribution of selected metallic restorative dentistry materials to X-ray fluorescence

Recent advances have led to the use of new materials in dental restoration which is an area of rapid growth. Applications include improving oral aesthetics and essential rehabilitation, whilst procedures range from the recovery of partial elements (inlays) to fitting dental implants. Ceramics, polymers and metallic materials have all been successfully employed in dental applications and benefit from new cost efficient manufacturing techniques. The application of radiographic techniques in dentistry and other medicine is also increasing, and the combination of new materials and radiation can lead to an elevated health risk. X-rays can interact with metallic materials producing X-ray fluorescence, which can increase the radiation dose in proximity to restorative material and increase the risk of live biological tissue becoming cancerous. The issue demands consideration so that the biological risks associated with such procedures are kept as low as possible. Comparisons of doses calculated for several materials have provided evidence that the Ti cp and NiCrTi alloys present less contribution to the increase of dose in surrounding soft tissue and the potential deleterious biological effects. On the other hand, Amalgam appears to be the most deleterious alloy

Zwicky Transient Facility and Globular Clusters: The Period-Luminosity and Period-Wesenheit Relations for SX Phoenicis Variables in the gri-Band

SX Phoenicis (SXP) variables are short period pulsating stars that exhibit a period-luminosity (PL) relation. We derived the gri-band PL and extinction-free period-Wesenheit (PW) relations, as well as the period-color (PC) and reddening-free period-Q-index (PQ) relations for 47 SXP stars in located in 21 globular clusters using the optical light curves taken from Zwicky Transient Facility (ZTF). These empirically relations were derived for the first time in the gri filters except for the g-band PL relation. We used our gi band PL and PW relations to derive a distance modulus to Crater II dwarf spheroidal which hosts one SXP variable. Assuming that the fundamental and first-overtone pulsation mode for the SXP variable in Crater II, we found distance moduli of $20.03 \pm 0.23$ mag and $20.37 \pm 0.24$ mag, respectively, using the PW relation, where the latter is in excellent agreement with independent RR Lyrae based distance to Crater II dwarf galaxy.Comment: 12 pages, 1 Table and 10 Figures; AJ accepte

Cost-effective approach to lung cancer risk for a radiological dispersal device (RDD) scenario

A release of radioactive material into the environment can lead to hazardous exposure of the population and serious future concerns about health issues such as an increased incidence of cancer. In this context, a practical methodology capable of providing useful basic information from the scenario can be valuable for immediate decisions and future risk assessment. For this work, the simulation of a radiological dispersal device (RDD) filled with americium-241 was considered. The radiation dose simulated by the HotSpot code was used as an input to the epidemiological equations from BEIR V producing the data used to assess the risk of lung cancer development. The methodology could be useful in providing training for responders aimed to the initial support addressed to decision-making for emergency response at the early phase of an RDD scenario. The results from the simulation allow estimating (a) the size of the potentially affected population, (b) the type of protection action considering gender and location of the individuals, (c) the absorbed doses, (d) the matrix of lung cancer incidence predictions over a period of 5 years, and (e) the cost-effectiveness in the initial decision environment

Composition of UHECR and the Pierre Auger Observatory Spectrum

We fit the recently published Pierre Auger ultra-high energy cosmic ray spectrum assuming that either nucleons or nuclei are emitted at the sources. We consider the simplified cases of pure proton, or pure oxygen, or pure iron injection. We perform an exhaustive scan in the source evolution factor, the spectral index, the maximum energy of the source spectrum Z E_{max}, and the minimum distance to the sources. We show that the Pierre Auger spectrum agrees with any of the source compositions we assumed. For iron, in particular, there are two distinct solutions with high and low E_{max} (e.g. 6.4 10^{20} eV and 2 10^{19} eV) respectively which could be distinguished by either a large fraction or the near absence of proton primaries at the highest energies. We raise the possibility that an iron dominated injected flux may be in line with the latest composition measurement from the Pierre Auger Observatory where a hint of heavy element dominance is seen.Comment: 19 pages, 6 figures (33 panels)- Uses iopart.cls and iopart12.clo- In version 2: addition of a few sentences and two reference

Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis

Regulation of cutaneous immunity is severely compromised in inflammatory skin disease. To investigate the molecular crosstalk underpinning tolerance versus inflammation in atopic dermatitis, we utilise a human in vivo allergen challenge study, exposing atopic dermatitis patients to house dust mite. Here we analyse transcriptional programmes at the population and single cell levels in parallel with immunophenotyping of cutaneous immunocytes revealed a distinct dichotomy in atopic dermatitis patient responsiveness to house dust mite challenge. Our study shows that reactivity to house dust mite was associated with high basal levels of TNF-expressing cutaneous Th17 T cells, and documents the presence of hub structures where Langerhans cells and T cells co-localised. Mechanistically, we identify expression of metallothioneins and transcriptional programmes encoding antioxidant defences across all skin cell types, that appear to protect against allergen-induced inflammation. Furthermore, single nucleotide polymorphisms in the MTIX gene are associated with patients who did not react to house dust mite, opening up possibilities for therapeutic interventions modulating metallothionein expression in atopic dermatitis