5,944 research outputs found
EAST: An Efficient and Accurate Scene Text Detector
Previous approaches for scene text detection have already achieved promising
performances across various benchmarks. However, they usually fall short when
dealing with challenging scenarios, even when equipped with deep neural network
models, because the overall performance is determined by the interplay of
multiple stages and components in the pipelines. In this work, we propose a
simple yet powerful pipeline that yields fast and accurate text detection in
natural scenes. The pipeline directly predicts words or text lines of arbitrary
orientations and quadrilateral shapes in full images, eliminating unnecessary
intermediate steps (e.g., candidate aggregation and word partitioning), with a
single neural network. The simplicity of our pipeline allows concentrating
efforts on designing loss functions and neural network architecture.
Experiments on standard datasets including ICDAR 2015, COCO-Text and MSRA-TD500
demonstrate that the proposed algorithm significantly outperforms
state-of-the-art methods in terms of both accuracy and efficiency. On the ICDAR
2015 dataset, the proposed algorithm achieves an F-score of 0.7820 at 13.2fps
at 720p resolution.Comment: Accepted to CVPR 2017, fix equation (3
QuAC : Question Answering in Context
We present QuAC, a dataset for Question Answering in Context that contains
14K information-seeking QA dialogs (100K questions in total). The dialogs
involve two crowd workers: (1) a student who poses a sequence of freeform
questions to learn as much as possible about a hidden Wikipedia text, and (2) a
teacher who answers the questions by providing short excerpts from the text.
QuAC introduces challenges not found in existing machine comprehension
datasets: its questions are often more open-ended, unanswerable, or only
meaningful within the dialog context, as we show in a detailed qualitative
evaluation. We also report results for a number of reference models, including
a recently state-of-the-art reading comprehension architecture extended to
model dialog context. Our best model underperforms humans by 20 F1, suggesting
that there is significant room for future work on this data. Dataset, baseline,
and leaderboard available at http://quac.ai.Comment: EMNLP Camera Read
First R and I Lights and Their Photometric Analyses of GSC 02393-00680
We obtained complete and light curves of GSC 02393-00680 in 2008 and
analyzed them with the 2003 version of the W-D code. It is shown that GSC
02393-00680 is a W-type shallow contact binary system with a high mass ratio
and a degree of contact factor . It will be a good
example to check up on the TRO theory. A period investigation based on all
available data suggests that the system has a small-amplitude period
oscillation (; years). This may indicate it has a
moderate mass close third body, which is similar to XY Leo
6-(4-Fluorophenethyl)-7-imino-3-phenyl-2,3,6,7-tetrahydro-1,3-thiazolo[4,5-d]pyrimidine-2-thione
In the title compound, C19H15FN4S2, the mean plane of the thiazolopyrimidine makes a dihedral angle of 77.6 (1)° with the attached phenyl ring. The crystal packing is stabilized by intermolecular C—H⋯N hydrogen bonds and weak C—H—π stacking interactions
The first record of the family Euscorpiidae (Arachnida: Scorpiones) from Central China, with a key of Chinese species of the genus \u3cem\u3eScorpiops\u3c/em\u3e
The genus Scorpiops (Euscorpiidae) is recorded for the first time in Central China. Two immature specimens of a form belonging to Scorpiops hardwickii (Gervais, 1843) “complex” were collected from Huzhaoshan Mountains in Hubei Province. A discussion of Chinese species of genus Scorpiops is provided, as well as a key of Scorpiops from China
Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: Pro-survival role of Ambra1
Recent research has revealed a role for Ambra1, an autophagy-related gene-related (ATG) protein, in the autophagic pro-survival response, and Ambra1 has been shown to regulate Beclin1 and Beclin1-dependent autophagy in embryonic stem cells. However, whether Ambra1 plays an important role in the autophagy pathway in colorectal cancer cells is unknown. In this study, we hypothesized that Ambra1 is an important regulator of autophagy and apoptosis in CRC cell lines. To test this hypothesis, we confirmed autophagic activity in serum-starved SW620 CRC cells by assessing endogenous microtubule-associated protein 1 light chain 3 (LC3) localization, the presence of autophagosomes (transmission electron microscopy) and LC3 protein levels (Western blotting). Ambra1 expression was detected by Western blot in SW620 cells treated with staurosporine or etoposide. Calpain and caspase inhibitors were employed to verify whether calpains and caspases were responsible for Ambra1 cleavage. To examine the role of Ambra1 in apoptosis, Ambra1 knockdown cells were treated with staurosporine and etoposide. Cell apoptosis and viability were measured by annexin-V and PI staining and MTT assays. We determined that serum deprivation-induced autophagy was associated with Ambra1 upregulation in colorectal cancer cell lines. Ambra1 expression decreased during staurosporine- or etoposide-induced apoptosis. Calpains and caspases may be responsible for Ambra1 degradation. When Ambra1 expression was reduced by siRNA, SW620 cells were more sensitive to staurosporine- or etoposide-induced apoptosis. In addition, starvation-induced autophagy decreased. Finally, Co-immunoprecipitation of Ambra1 and Beclin1 demonstrated that Ambra1 and Beclin1 interact in serum-starved or rapamycin-treated SW620 cells, suggesting that Ambra1 regulates autophagy in CRC cells by interacting with Beclin1. In conclusion, Ambra1 is a crucial regulator of autophagy and apoptosis in CRC cells that maintains the balance between autophagy and apoptosis
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