Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates

BACKGROUND: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information transfer process. RESULTS: Primer sequence is converted to a vector of the full potential hydrogen numbers (3 for G or C, 2 for A or T), while template sequence is converted to a vector of the actual hydrogen bond numbers formed after primer annealing. The former is considered as source information and the latter destination information. An information coefficient is calculated as a measure for fidelity of this information transfer process and thus a measure of similarity between primer and potential annealing site on template. CONCLUSION: Successful prediction of PCR products from whole genomic sequences with a computer program based on the algorithm demonstrated the potential of this new algorithm in areas like in silico PCR and gene finding

Neural network with added inertia for linear complementarity problem

In this brief, considering the inertial term into first order neural networks(NNs), an inertial NN(INN) modeled by means of a differential inclusion is proposed for solving linear complementarity problem with P-0 matrix. Compared with existing NNs, the presence of the inertial term allows us to overcome some drawbacks of many NNs, which are constructed based on the steepest descent method, and this model is more convenient for exploring different optimal solution. It is proved that the proposed NN is stable in the sense of Lyapunov and any equilibrium of our NN is the optimal solution of LCP with P-0 matrix. Simulation results on two numerical examples show the effectiveness and performance of the proposed neural network

Modeling Computer Virus and Its Dynamics

Based on that the computer will be infected by infected computer and exposed computer, and some of the computers which are in suscepitible status and exposed status can get immunity by antivirus ability, a novel coumputer virus model is established. The dynamic behaviors of this model are investigated. First, the basic reproduction number R0, which is a threshold of the computer virus spreading in internet, is determined. Second, this model has a virus-free equilibrium P0, which means that the infected part of the computer disappears, and the virus dies out, and P0 is a globally asymptotically stable equilibrium if R0<1. Third, if R0>1 then this model has only one viral equilibrium P*, which means that the computer persists at a constant endemic level, and P* is also globally asymptotically stable. Finally, some numerical examples are given to demonstrate the analytical results

Research Progress and Application of Single-Atom Catalysts: A Review

Due to excellent performance properties such as strong activity and high selectivity, single-atom catalysts have been widely used in various catalytic reactions. Exploring the application of single-atom catalysts and elucidating their reaction mechanism has become a hot area of research. This article first introduces the structure and characteristics of single-atom catalysts, and then reviews recent preparation methods, characterization techniques, and applications of single-atom catalysts, including their application potential in electrochemistry and photocatalytic reactions. Finally, application prospects and future development directions of single-atom catalysts are outlined

Bearing Fault Diagnosis Based on Spatial Features of 2.5 Dimensional Sound Field

The traditional acoustic-based diagnosis (ABD) technique based on single-channel testing has a significant engineering value. Since its diagnosis robustness is sensitive to sound signal acquisition location, it develops slowly. To solve this problem, the 2-dimensional (2D) sound field variation near the machine is adopted for diagnosis by the near-field acoustic holography (NAH)- based fault diagnosis method with array measurement. However, its performance is limited due to the neglect of the sound field normal change information. To dig the sound field fault information further, a 2.5-dimensional (2.5D) acoustic field diagnosis method is presented in this paper and its performance compared with the 2D technology is verified by the bearing diagnostic test. Different from the 2D technique with only one source image, the 2.5D acoustic field model consists of source image, holographic sound image, and the differences between them, and its effective feature model is constructed by Gabor wavelet feature extraction and random forest feature reduction algorithm. The diagnostic effect of the 2.5D technique compared with the 2D technique increases more than 11% in the bearing diagnostic test. It provides new ideas for the development of the NAH-based fault diagnosis method, and further improves the ABD technique-based array measurement

Driver Identification Methods in Electric Vehicles, a Review

Driver identification is very important to realizing customized service for drivers and road traffic safety for electric vehicles and has become a research hotspot in the field of modern automobile development and intelligent transportation. This paper presents a comprehensive review of driver identification methods. The basic process of driver identification task is proposed as four steps, the advantages and disadvantages of different data sources for driver identification are analyzed, driver identification models are divided into three categories, and the characteristics and research progress of driver identification models are summarized, which can provide a reference for further research on driver identification. It is concluded that on-board sensor data in the natural driving state is objective and accurate and could be the main data source for driver identification. Emerging technologies such as big data, artificial intelligence, and the internet of things have contributed to building a deep learning hybrid model with high accuracy and robustness and representing an important gradual development trend of driver identification methods. Developing a driver identification method with high accuracy, real-time performance, and robustness is an important development goal in the future

A recurrent neural network for solving bilevel linear programming problem

In this brief, based on the method of penalty functions, a recurrent neural network (NN) modeled by means of a differential inclusion is proposed for solving the bilevel linear programming problem (BLPP). Compared with the existing NNs for BLPP, the model has the least number of state variables and simple structure. Using nonsmooth analysis, the theory of differential inclusions, and Lyapunov-like method, the equilibrium point sequence of the proposed NNs can approximately converge to an optimal solution of BLPP under certain conditions. Finally, the numerical simulations of a supply chain distribution model have shown excellent performance of the proposed recurrent NNs