480 research outputs found
Autonomous satellite docking system
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76348/1/AIAA-2001-4527-378.pd
A Nonstandard Fourier Inequality
We consider a class of functions given by a class of generalized Fourier series which arise in the study of sampled-data control. These functions are continuous on the real line, but not differentiable at x=0. We prove that for all sufficiently small x \u3e 0, these functions are larger than a constant times the square root of x
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Properties of Multivesicular Release from Mouse Rod Photoreceptors Support Transmission of Single-Photon Responses
Vision under starlight requires rod photoreceptors to transduce and transmit single-photon responses to the visual system. Small single-photon voltage changes must therefore cause detectable reductions in glutamate release. We found that rods achieve this by employing mechanisms that enhance release regularity and its sensitivity to small voltage changes. At the resting membrane potential in darkness, mouse rods exhibit coordinated and regularly timed multivesicular release events, each consisting of ~17 vesicles and occurring two to three times more regularly than predicted by Poisson statistics. Hyperpolarizing rods to mimic the voltage change produced by a single photon abruptly reduced the probability of multivesicular release nearly to zero with a rebound increase at stimulus offset. Simulations of these release dynamics indicate that this regularly timed, multivesicular release promotes transmission of single-photon responses to post-synaptic rod-bipolar cells. Furthermore, the mechanism is efficient, requiring lower overall release rates than uniquantal release governed by Poisson statistics
LASER SAFETY FOR THE EXPERIMENTAL HALLS AT SLAC’S LINAC COHERENT LIGHT SOURCE (LCLS) *
The LCLS at the SLAC National Accelerator Laboratory will be the world’s first source of an intense hard x-ray laser beam, generating x-rays with wavelengths of 1nm and pulse durations less than 100fs. The ultrafast x-ray pulses will be used in pump-probe experiments to take stop-motion pictures of atoms and molecules in motion, with pulses powerful enough to take diffraction images of single molecules, enabling scientists to elucidate fundamental processes of chemistry and biology. Ultrafast conventional lasers will be used as the pump. In 2009, LCLS will deliver beam to the Atomic Molecular and Optical (AMO) Experiment, located in one of 3 x-ray Hutches in the Near Experimental Hall (NEH). The NEH includes a centralized Laser Hall, containing up to three Class 4 laser systems, three x-ray Hutches for experiments and vacuum transport tubes for delivering laser beams to the Hutches. The main components of the NEH laser systems are a Ti:sapphire oscillator, a regen amplifier, green pump lasers for the oscillator and regen, a pulse compressor and a harmonics conversion unit. Laser safety considerations and controls for the ultrafast laser beams, multiple laser controlled areas, and user facility issues are discussed
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Development of a Web-Based Interactive Tool for Visualizing Breast Cancer Clinical Trial Tolerability Data
PurposeLongitudinal patient tolerability data collected as part of randomized controlled trials are often summarized in a way that loses information and does not capture the treatment experience. To address this, we developed an interactive web application to empower clinicians and researchers to explore and visualize patient tolerability data.MethodsWe used adverse event (AE) data (Common Terminology Criteria for Adverse Events) and patient-reported outcomes (PROs) from the NSABP-B35 phase III clinical trial, which compared anastrozole with tamoxifen for breast cancer-free survival, to demonstrate the tools. An interactive web application was developed using R and the Shiny web application framework that generates Sankey diagrams to visualize AEs and PROs using four tools: AE Explorer, PRO Explorer, Cohort Explorer, and Custom Explorer.ResultsTo illustrate how users can use the interactive tool, examples for each of the four applications are presented using data from the NSABP-B35 phase III trial and the NSABP-B30 trial for the Custom Explorer. In the AE and PRO explorers, users can select AEs or PROs to visualize within specified time periods and compare across treatments. In the cohort explorer, users can select a subset of patients with a specific symptom, severity, and treatment received to visualize the trajectory over time within a specified time interval. With the custom explorer, users can upload and visualize structured longitudinal toxicity and tolerability data.ConclusionWe have created an interactive web application and tool for clinicians and researchers to explore and visualize clinical trial tolerability data. This adaptable tool can be extended for other clinical trial data visualization and incorporated into future patient-clinician interactions regarding treatment decisions
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Laser Safety for the Experimental Halls at SLAC_s Linac Coherent Light Source (LCLS)
The LCLS at the SLAC National Accelerator Laboratory will be the world's first source of an intense hard x-ray laser beam, generating x-rays with wavelengths of 1nm and pulse durations less than 100fs. The ultrafast x-ray pulses will be used in pump-probe experiments to take stop-motion pictures of atoms and molecules in motion, with pulses powerful enough to take diffraction images of single molecules, enabling scientists to elucidate fundamental processes of chemistry and biology. Ultrafast conventional lasers will be used as the pump. In 2009, LCLS will deliver beam to the Atomic Molecular and Optical (AMO) Experiment, located in one of 3 x-ray Hutches in the Near Experimental Hall (NEH). The NEH includes a centralized Laser Hall, containing up to three Class 4 laser systems, three x-ray Hutches for experiments and vacuum transport tubes for delivering laser beams to the Hutches. The main components of the NEH laser systems are a Ti:sapphire oscillator, a regen amplifier, green pump lasers for the oscillator and regen, a pulse compressor and a harmonics conversion unit. Laser safety considerations and controls for the ultrafast laser beams, multiple laser controlled areas, and user facility issues are discussed
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Interactive tensor field design and visualization on surfaces
Designing tensor fields in the plane and on surfaces
is a necessary task in many graphics applications, such as
painterly rendering, pen-and-ink sketch of smooth surfaces, and
anisotropic remeshing. In this paper, we present an interactive
design system that allows a user to create a wide variety of
surface tensor fields with control over the number and location
of degenerate points. Our system combines basis tensor fields
to make an initial tensor field that satisfies a set of user specifications.
However, such a field often contains unwanted
degenerate points that cannot always be eliminated due to
topological constraints of the underlying surface. To reduce the
artifacts caused by these degenerate points, our system allows the
user to move a degenerate point or to cancel a pair of degenerate
points that have opposite tensor indices.
We observe that a tensor field can be locally converted into
a vector field such that there is a one-to-one correspondence
between the set of degenerate points in the tensor field and the
set of singularities in the vector field. This conversion allows
us to effectively perform degenerate point pair cancellation
and movement by using similar operations for vector fields. In
addition, we adapt the image-based flow visualization technique
to tensor fields, therefore allowing interactive display of tensor
fields on surfaces.
We demonstrate the capabilities of our tensor field design
system with painterly rendering, pen-and-ink sketch of surfaces,
and anisotropic remeshing.Keywords: Tensor field design and visualization, nonphotorealistic rendering, tensor field topology, remeshin
Echoes without resonance:Critiquing certain aspects of recent scholarly trends in the study of the Jewish scriptures in the New Testament
sagepub.co.uk/journalsPermissions.na
Detritus: An exhibition of art from recycled or found art materials
Catalog for the exhibition Detritus: An exhibition of art from recycled or found art materials held at the Seton Hall University Walsh Gallery, April 16 – May 25, 2007. Curated by Mark Schlemmer, Kelsey Quillen and Laura Browarney. Includes an essay by Mark Schlemmer, Kelsey Quillen and Laura Browarney. Includes color illustrations
Plasma Cleaning of LCLS-II-HE verification cryomodule cavities
Plasma cleaning is a technique that can be applied in superconducting
radio-frequency (SRF) cavities in situ in cryomodules in order to decrease
their level of field emission. We developed the technique for the Linac
Coherent Light Source II (LCLS-II) cavities and we present in this paper the
full development and application of plasma processing to the LCLS-II High
Energy (HE) verification cryomodule (vCM). We validated our plasma processing
procedure on the vCM, fully processing four out of eight cavities of this CM,
demonstrating that cavities performance were preserved in terms of both
accelerating field and quality factor. Applying plasma processing to this
clean, record breaking cryomodule also showed that no contaminants were
introduced in the string, maintaining the vCM field emission-free up to the
maximum field reached by each cavity. We also found that plasma processing
eliminates multipacting (MP) induced quenches that are typically observed
frequently within the MP band field range. This suggests that plasma processing
could be employed in situ in CMs to mitigate both field emission and
multipacting, significantly decreasing the testing time of cryomodules, the
linac commissioning time and cost and increasing the accelerator reliability.Comment: 11 pages, 10 figure
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