Histocompatibility Testing in Renal Transplantation

The effect of HLA matching and other aspects of histocompatibility on renal graft survival were analyzed in 144 patients who received renal transplants at Henry Ford Hospital during the past ten years. Living related transplants with one haplotype match or better demonstrated a higher graft survival rate (at least 88%) at one year than the better matched cadaveric transplant. In cadaveric transplants, the group with fewer than two mismatched antigens appeared to have a higher graft survival rate than those with more than two. The patient population was not large enough to determine the effect of preformed antibodies, ABO grouping, or other recipient factors on graft survival

C-Reactive Protein: Potential Significance of Quantitation in Patients with Chronic Diseases

Serum C-reactive protein (CRP) levels in 351 patients with certain chronic diseases were assayed by a micro-double immunodiffusion technique developed and used in this hospital. Elevation of CRP values and severity of disease were evident in the following clinical entities: 31 of 54 patients (57%) with liver cirrhosis; 122 of 204 (60%) hepatitis patients; 34 of 52 (65%) patients with gastro-intestinal surgery; 8 of 21 (38%) uremic patients; and all of 20 patients with renal transplantation. There was good correlation between markedly elevated serum CRP values and degree of inflammation and/or physiologic stress during clinical course and recovery

Efficacy of Betaprone with Ultraviolet Irradiation on Hepatitis B Antigen in Human Plasma Pools (A Retrospective Study)

In a retrospective study, hepatitis B antigen (HB Ag) was found in 14 lots of human plasma pools (16-20 liters each) that had been treated by the combined Betaprone (BPL) with ultraviolet (UV) irradiation procedure. No evidence of clinical hepatitis was found during a six-month follow-up after 185.2 liters of HB Ag positive plasma were Infused into 257 patients. Since HB Ag positive blood products treated by BPL with UV produced no clinical hepatitis, it is evident that our treatment is efficacious against hepatitis virus agents

Stabilizing Control for Power Systems by Means of Superconducting Magnetic Energy Storage

This paper represents the stabilizing control for electric power systems by means of the superconducting magnetic energy storage (SMES). After describing the concept of stabilization by the SMES, using the simplest power system model, we show a method for analyzing a more complex model of power systems including the SMES. As for the stabilizing control methods, we propose the bang-bang control of the control angle a of the SMES thyristor bridge, and the control of α by the feedback of the angular velocity deviation ⊿ω of the generator rotor. We then apply them to a one-machine infinite-bus system to examine their effects. After that, the system's damping effects of the feedback control of the SMES on a multi-machine system are investigated, using a sample 10-machine system. Lastly, the relationship between the SMES location and the damping effect is discussed

Quantitative Determination of C-Reactive Protein (CRP) by Micro-Double Diffusion Technic

C-reactive protein (CRP) determinations in serum have been evaluated by two methods: the capillary tube method (presently in use) and the double diffusion technic (a newly developed procedure standardized in this laboratory). Advantages of the double diffusion technic are (1) quantitation of CRP in milligrams per 100 ml of serum, (2) differentiation of CRP from non-specific precipitates often found in patients\u27 sera, and (3) increased sensitivity. A normal range of CRP levels has been established by analyzing serum from 750 supposedly healthy blood bank donors. Ninety-five percent of the donor population possess less than 1.0 mg of CRP per 100 ml of serum (53% are negative, 23% with trace quantities and 19% with 0.2-1.0 mg per 100 ml of serum). CRP serum levels above 1.0 mg per 100 ml are significant values for clinical interpretation

Stabilization of Longitudinal Power System by Means of Superconducting Magnetic Energy Storage

A power system stabilization by means of the superconducting magnetic energy storage (SMES) has already been proposed, wherein the firing angle α of the SMES thyristor bridge is controlled, based on the angular velocity deviation ⊿ω of the generator rotor. In this paper, a simple longitudinal system is taken up as a sample system, and the optimum position of the SMES is investigated from the stabilizing point of view. Also studied is the effect of the distributed installation of the SMES from both sides of the steady-state stability by means of the eigenvalue method, and the transient stability by the simulation method