21,034 research outputs found

    Rotor redesign for a highly loaded 1800 ft/sec tip speed fan. 3: Laser Doppler velocimeter report

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    Laser Doppler velocimeter (LDV) techniques were employed for testing a highly loaded, 550 m/sec (1800 ft/sec) tip speed, test fan stage, the objective to provide detailed mapping of the upstream, intrablade, and downstream flowfields of the rotor. Intrablade LDV measurements of velocity and flow angle were obtained along four streamlines passing through the leading edge at 45%, 69%, 85%, and 95% span measured from hub to tip, at 100% of design speed, peak efficiency; 100% speed, near surge; and 95% speed, peak efficiency. At the design point, most passages appeared to have a strong leading edge shock, which moved forward with increasing strength near surge and at part speeds. The flow behind the shock was of a complex mixed subsonic and supersonic form. The intrablade flowfields were found to be significantly nonperiodic at 100% design speed, peak efficiency

    ND4: ASSESSING UTILITIES FOR DEPRESSION OUTCOMES: PREFERENCES OF DEPRESSED PATIENTS AND THE GENERAL PUBLIC

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    Critical Kauffman networks under deterministic asynchronous update

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    We investigate the influence of a deterministic but non-synchronous update on Random Boolean Networks, with a focus on critical networks. Knowing that ``relevant components'' determine the number and length of attractors, we focus on such relevant components and calculate how the length and number of attractors on these components are modified by delays at one or more nodes. The main findings are that attractors decrease in number when there are more delays, and that periods may become very long when delays are not integer multiples of the basic update step.Comment: 8 pages, 3 figures, submitted to a journa

    Magnetohydrodynamic evolution of magnetic skeletons

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    The heating of the solar corona is likely to be due to reconnection of the highly complex magnetic field that threads throughout its volume. We have run a numerical experiment of an elementary interaction between the magnetic field of two photospheric sources in an overlying field that represents a fundamental building block of the coronal heating process. The key to explaining where, how and how much energy is released during such an interaction is to calculate the resulting evolution of the magnetic skeleton. A skeleton is essentially the web of magnetic flux surfaces (called separatrix surfaces) that separate the coronal volume into topologically distinct parts. For the first time the skeleton of the magnetic field in a 3D numerical MHD experiment is calculated and carefully analysed, as are the ways in which it bifurcates into different topologies. A change in topology normally changes the number of magnetic reconnection sites. In our experiment, the magnetic field evolves through a total of six distinct topologies. Initially, no magnetic flux joins the two sources. Then a new type of bifurcation, called a global double-separator bifurcation, takes place: this bifurcation is likely to be one of the main ways in which new separators are created in the corona (separators are field lines at which 3D reconnection takes place). This is the first of five bifurcations in which the skeleton becomes progressively more complex before simplifying. Surprisingly, for such a simple initial state, at the peak of complexity there are five separators and eight flux domains present.Comment: 18 pages, 5 figure

    Secondary school educational practitioners’ experiences of school attendance problems and interventions to address them: A qualitative study

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    This is the author accepted manuscript. The final version is available from Taylor & Francis (Routledge) via the DOI in this record.School attendance problems are associated with a range of adverse consequences, and educational practitioners play a role in identifying and responding to attendance problems. This qualitative study explored educational practitioners’ experiences of working with students with attendance problems and interventions to address them. Focus groups were conducted with sixteen practitioners across three secondary schools. Data were analysed using thematic analysis. Attendance problems were considered resource-intensive and emotionally challenging. Practitioners expressed difficulty understanding causes, although individual/family factors were emphasised over school factors. A range of interventions were described, including adaptations to school context and providing emotional support. Views on punitive approaches were mixed. Individualised interventions implemented at the first sign of problems, and a team approach, were considered important. Findings highlight the important role of educational practitioners in identifying attendance problems and implementing interventions. Recommendations include early intervention, team-work, and emotional support for students with, and staff responding to, attendance problems.This work was supported by a PhD studentship from the University of Exeter Medical School, UK

    New BPS Solitons in 2+1 Dimensional Noncommutative CP^1 Model

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    Investigating the solitons in the non-commutative CP1CP^{1} model, we have found a new set of BPS solitons which does not have counterparts in the commutative model.Comment: 8 pages, LaTeX2e, references added, improvements to discussions, Version to be published in JHE

    Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro

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    AbstractRecombinant adeno-associated viral (rAAV) vectors are frequently used for gene delivery to the central nervous system and are capable of transducing neurons and glia in vitro. In this study, seven serotypes of a rAAV vector expressing green fluorescent protein (GFP) were characterized for tropism and toxicity in primary cortical cells derived from embryonic rat brain. At 2 days after transduction, serotypes 1 and 5 through 8 expressed GFP predominately in glia, but by 6 days post-transduction expression was neuronal except for AAV5. AAV2 and 9 produced minimal GFP expression. Using cell viability assays, toxicity was observed at higher multiplicities of infection (MOI) for all serotypes except AAV2 and 9. The toxicity of AAV1 and 5–8 affected mostly glia as indicated by a loss of glial-marker immunoreactivity. A frameshift mutation in the GFP gene reduced overall toxicity for serotypes 1, 5 and 6, but not 7 and 8 suggesting that the toxicity was not solely due to the overexpression of GFP. Collectively, a differential tropism and toxicity was observed among the AAV serotypes on primary cortical cultures with an overall preferential glial transduction and toxicity
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