200 research outputs found
The Teaching Standards Movement and Current Teaching Practices
In contrast to curriculum standards initiatives, the teaching standards movement advocates a broad teaching approach that includes teaching for understanding, skills development in context, collaborative activities, and diversity of content and method. Using this conceptualization to analyze teachersâ responses to a survey, we found that their practices reflected the teaching standards approach. In discussing our findings, we note that an awareness of teachersâ current achievements might reduce negative views of the profession, and that teachers need support to continue to develop in the teaching standards direction. Keywords: teaching standards, school renewal, literacy teaching, mathematics teaching Contrairement aux initiatives en matiĂšre de normes de rĂ©fĂ©rence curriculaire, le mouvement de lâenseignement standardisĂ© plaide pour une approche dâenseignement Ă©tendue qui inclue lâenseignement de la comprĂ©hension, le dĂ©veloppement des habiletĂ©s en contexte, les activitĂ©s collaboratives et la diversitĂ© du contenu et des mĂ©thodes. En utilisant cette conceptualisation dans lâanalyse des rĂ©ponses Ă lâenquĂȘte par les enseignants, nous avons trouvĂ© que leur pratique enseignante reflĂšte lâapproche de lâenseignement standardisĂ©. Dans la discussion de nos rĂ©sultats, nous observons quâune prise de conscience des accomplissements actuels des enseignants risque de rĂ©duire les opinions nĂ©gatives sur la profession enseignante et que les enseignants ont besoin de soutien pour continuer de se dĂ©velopper dans la direction de lâenseignement normalisĂ©. Mots-clĂ©s : enseignement standardisĂ©, renouvellement scolaire, enseignement de lâalphabĂ©tisation, enseignement des mathĂ©matiques
An effective route to the additive manufacturing of a mechanically gradient supramolecular polymer nanocomposite structure
3D Printing techniques are additive methods of fabricating parts directly from computer-aided designs. Whilst the clearest benefit is the realisation of geometrical freedom, multi-material printing allows the introduction of compositional variation and highly tailored product functionality. The paper reports a proof-of-concept additive manufacturing study to deposit a supramolecular polymer and a complementary organic filler to form composites with gradient composition to enable spatial distribution of mechanical properties and functionality by tuning the number of supramolecular interactions. We use a dual-feed extrusion 3D printing process, with feed stocks based on the supramolecular polymer and its organic composite, delivered at ratios predetermined. This allows for production of a graded specimen with varying filler concentration that dictates the mechanical properties. The printed specimen was inspected under dynamic load in a tensile test using digital image correlation to produce full-field deformation maps, which showed clear differences in deformation in regions with varying compositions, corresponding to the designed-in variations. This approach affords a novel method for printing material with graded mechanical properties which are not currently commercially available or easily accessible, however, the method can potentially be directly translated to the generation of biomaterial-based composites featuring gradients of mechanical properties
Structural, item, and test generalizability of the psychopathology checklist - revised to offenders with intellectual disabilities
The Psychopathy ChecklistâRevised (PCL-R) is the most widely used measure of psychopathy in forensic clinical practice, but the generalizability of the measure to offenders with intellectual disabilities (ID) has not been clearly established. This study examined the structural equivalence and scalar equivalence of the PCL-R in a sample of 185 male offenders with ID in forensic mental health settings, as compared with a sample of 1,212 male prisoners without ID. Three models of the PCL-Râs factor structure were evaluated with confirmatory factor analysis. The 3-factor hierarchical model of psychopathy was found to be a good fit to the ID PCL-R data, whereas neither the 4-factor model nor the traditional 2-factor model fitted. There were no cross-group differences in the factor structure, providing evidence of structural equivalence. However, item response theory analyses indicated metric differences in the ratings of psychopathy symptoms between the ID group and the comparison prisoner group. This finding has potential implications for the interpretation of PCL-R scores obtained with people with ID in forensic psychiatric settings
Microstructures in subglacial and proglacial sediments : understanding faults, folds and fabrics, and the influence of water on the style of deformation
Macroscopic field and micromorphological studies have been carried out on subglacially and proglacially deformed glacigenic sequences at a number of sites throughout Scotland, UK. Examination of microstructures (folds, faults, hydrofractures, plasmic fabrics) aided understanding of the deformation histories preserved in the sediments, but a similar range of structures were developed in both subglacial and proglacial settings. Discrimination between subglacial and proglacial deformation was only possible when micromorphological data was used in conjunction with larger-scale field observations. Variations in lithology and water content were controlling factors influencing the style and apparent intensity of deformation recorded. Changes in pore-water content and pressure during deformation can lead to liquefaction and hydrofracturing, with early formed structures locally controlling the pattern of water-escape. Liquefaction can also lead to homogenisation of the sediments and the destruction of earlier deformation structures, even at relatively low strains. Beds or zones of liquefied sand and silt may form highly âlubricatedâ detachments within the sediment pile, resulting in a marked reduction in the amount of shear transmitted to underlying units. A multidisciplinary approach, involving sedimentological, geomorphological, stratigraphical and structural field observations, combined with micromorphological analysis, is recommended to confidently unravel the glacitectonic history and depositional environment of most deformed glacigenic sedimentary sequences
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An effective route to the additive manufacturing of a mechanically gradient supramolecular polymer nanocomposite structure
3D Printing techniques are additive methods of fabricating parts directly from computer-aided designs. Whilst the clearest benefit is the realisation of geometrical freedom, multi-material printing allows the introduction of compositional variation and highly tailored product functionality. The paper reports a proof-of-concept additive manufacturing study to deposit a supramolecular polymer and a complementary organic filler to form composites with gradient composition to enable spatial distribution of mechanical properties and functionality by tuning the number of supramolecular interactions. We use a dual-feed extrusion 3D printing process, with feed stocks based on the supramolecular polymer and its organic composite, delivered at ratios predetermined. This allows for production of a graded specimen with varying filler concentration that dictates the mechanical properties. The printed specimen was inspected under dynamic load in a tensile test using digital image correlation to produce full-field deformation maps, which showed clear differences in deformation in regions with varying compositions, corresponding to the designed-in variations. This approach affords a novel method for printing material with graded mechanical properties which are not currently commercially available or easily accessible, however, the method can potentially be directly translated to the generation of biomaterial-based composites featuring gradients of mechanical properties
Supplemental Income: British newspaper colour supplements in the 1960s
The introduction of colour supplements by three âqualityâ newspapers during the 1960s was a key development in the British press during the decade, and was described by the editor of the Sunday Times as âperhaps the most successful single innovation in post-war journalismâ. This article provides an overview of the advent of the colour supplements, explaining why they emerged when they did and developed in the manner they did, and exploring some of the difficulties and issues that attended their arrival. The article also demonstrates that sections of the British press were capable of taking advantage of changes in print and advertising culture brought about by the arrival of the post-war consumer society. However, the term âcolour supplementâ became pejorative shorthand for the perceived vacuity of this new society, in part because of the tension that existed between the editorial and advertising content of these modish new publications. Consequently, the success of the colour supplement experiment was not universally celebrated
Recording sympathetic nerve activity in conscious humans and other mammals:guidelines and the road to standardization
Over the past several decades, studies of the sympathetic nervous system in humans, sheep, rabbits, rats, and mice have substantially increased mechanistic understanding of cardiovascular function and dysfunction. Recently, interest in sympathetic neural mechanisms contributing to blood pressure control has grown, in part because of the development of devices or surgical procedures that treat hypertension by manipulating sympathetic outflow. Studies in animal models have provided important insights into physiological and pathophysiological mechanisms that are not accessible in human studies. Across species and among laboratories, various approaches have been developed to record, quantify, analyze, and interpret sympathetic nerve activity (SNA). In general, SNA demonstrates âburstingâ behavior, where groups of action potentials are synchronized and linked to the cardiac cycle via the arterial baroreflex. In humans, it is common to quantify SNA as bursts per minute or bursts per 100 heart beats. This type of quantification can be done in other species but is only commonly reported in sheep, which have heart rates similar to humans. In rabbits, rats, and mice, SNA is often recorded relative to a maximal level elicited in the laboratory to control for differences in electrode position among animals or on different study days. SNA in humans can also be presented as total activity, where normalization to the largest burst is a common approach. The goal of the present paper is to put together a summary of âbest practicesâ in several of the most common experimental models and to discuss opportunities and challenges relative to the optimal measurement of SNA across species. Listen to this article's corresponding podcast at https://ajpheart.podbean.com/e/guidelines-for-measuring-sympathetic-nerve-activity/ </jats:p
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish
Truncating mutations in the giant sarcomeric protein Titin result in dilated cardiomyopathy and skeletal myopathy. The most severely affected dilated cardiomyopathy patients harbor Titin truncations in the C-terminal two-thirds of the protein, suggesting that mutation position might influence disease mechanism. Using CRISPR/Cas9 technology, we generated six zebrafish lines with Titin truncations in the N-terminal and C-terminal regions. Although all exons were constitutive, C-terminal mutations caused severe myopathy whereas N-terminal mutations demonstrated mild phenotypes. Surprisingly, neither mutation type acted as a dominant negative. Instead, we found a conserved internal promoter at the precise position where divergence in disease severity occurs, with the resulting protein product partially rescuing N-terminal truncations. In addition to its clinical implications, our work may shed light on a long-standing mystery regarding the architecture of the sarcomere
The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) Prisons Project Study: protocol for a randomised controlled trial comparing methadone and buprenorphine for opiate detoxification
<p>Abstract</p> <p>Background</p> <p>In the United Kingdom (UK), there is an extensive market for the class 'A' drug heroin and many heroin users spend time in prison. People addicted to heroin often require prescribed medication when attempting to cease their drug use. The most commonly used detoxification agents in UK prisons are currently buprenorphine and methadone, both are recommended by national clinical guidelines. However, these agents have never been compared for opiate detoxification in the prison estate and there is a general paucity of research evaluating the most effective treatment for opiate detoxification in prisons. This study seeks to address this paucity by evaluating the most routinely used interventions amongst drug users within UK prisons.</p> <p>Methods/Design</p> <p>This study uses randomised controlled trial methodology to compare the open use of buprenorphine and methadone for opiate detoxification, given in the context of routine care, within three UK prisons. Prisoners who are eligible and give informed consent will be entered into the trial. The primary outcome will be abstinence status eight days after detoxification, as determined by a urine test. Secondary outcomes will be recorded during the detoxification and then at one, three and six months post-detoxification.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN58823759</p
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