1,157 research outputs found

    Typological disharmony and ergativity in Guajajara

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    From the introduction: The purpose of this paper is to present some results of research on Guajajara (G), a Tupi-Guarani language of Northeast Brazil, with the hope of contributing some facts of interest to universal grammarians. Guajajara is unique in that due to its particular combination of morphological and syntactic traits, it is inconsistent in terms of commonly discussed typological parameters. Some features of interest are: 1. Double cross-referencing of core NPs. a. General accusativity in cross-referencing pronominal clitics attached to the end of the clauses. b. Mixed ergativity with accusativity in the cross-referencing pronominal verb prefixes. 2. Registration in the verb of topicalization of oblique nominals. 3. The division of clauses into spans for the purposes of placement of tense, and other clitics, with no regard for the particular syntactic relation that the material of a span has to the clause as a whole. 4. The ergativity-accusativity splits, none of which are unique in themselves, but whose combination in G may be unique. Those splits are on the basis of independency-dependency of the verb, volitionality of the subject, on whether or not the subject of the dependent intransitive verb is the same as the subject of the independent verb, volitionality of the subject, and whether or not the subject of the dependent intransitive verb is the same as the subject of the independent verb, and on whether or not the verb in the sentence is preceded by an oblique nominal such as locative, or by an adverb. A split also may be conditioned on the relationship of object to subject on the agency hierarchy

    African American Women in Leadership Positions: A Qualitative Study

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    In today’s society, an accurate representation of female minority leadership is needed. This study explored the (a) leadership development of African American women, (b) means and hindrances that African American women leaders met on their pathway to success, and (c) role of resilience among African American women. The current research was guided by the Smith (2010) study; Smith completed research on this subject matter using African American males. The current research used women rather than men but maintained the same methodology. The Consensual Qualitative Research Method (CQR; Hill, Thompson, & Williams, 1997; Hill et al., 2005) was used to analyze archived interviews of two past African American female presidents of a national diversity mental health association to identify themes and constructs that emerged from the interviews. The themes and constructs were used to identify the leadership development, the means and hindrances, and the role of resilience among African American women. The results of the current study also indicated that (a) positive feedback/success experience, (b) mentorship, (c) good educational experiences (d) early leadership involvement, and (e) attendance at conventions were instrumental for the participants’ leadership development. The results of the current research are consistent with the Smith (2010) findings

    Hazard Analysis Study of Vehicle Impacts in a Chemical Plant

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    PresentationVehicles in chemical plants and refineries can be ignition sources for fires and explosions, particularly in situations involving crash impacts that cause chemical leakage. Generally, HAZOP methodology is used for facility risk evaluations, but HAZOP is inappropriate for mobile vehicles and normal protection systems or safeguards typically do not address such situations adequately. Thus, incidents caused by vehicle impacts can present a gap in a facility’s hazard assessment process. Hazards associated with vehicle incidents in a chemical plant were evaluated. An initial review revealed that there are few effective operational hazard-reduction actions that can be implemented, particularly for vehicle speeds over 40 mph. Therefore, speed control becomes the most important factor for risk reduction when selecting effective safeguards and providing hazard protection. Administrative actions such as controlling speed and limiting vehicle access to certain areas are suggested. Engineering controls include gate restrictions, ditches, berms, permanent and portable concrete barriers, guardrails, and bollards or posts to reduce risks associated with vehicle impacts. A list of suggested administrative and engineering controls is presented, along with a guideline for varied speed limits directed at reducing vehicle impacts, hence their associated risks and consequences. Hazard analysis teams can consider using this information as they conduct their reviews and make their recommendations

    Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

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    Diverse heterozygous mutations of bone morphogenetic receptor type II (BMPR-II) underlie the inherited form of the vascular disorder primary pulmonary hypertension (PPH). As yet, the molecular detail of how such defects contribute to the pathogenesis of PPH remains unclear. BMPR-II is a member of the transforming growth factor-beta cell signalling superfamily. Ligand binding induces cell surface receptor complex formation and activates a cascade of phosphorylation events of intracellular intermediaries termed Smads, which initiate transcriptional regulation. Some 30% of PPH-causing mutations localize to exon 12, which may be spliced out forming an isoform depleted of the unusually long BMPR-II cytoplasmic tail. To further elucidate the consequences of BMPR2 mutation, we sought to characterize aspects of the cytoplasmic domain function by seeking intracellular binding partners. We now report that Tctex-1, a light chain of the motor complex dynein, interacts with the cytoplasmic domain of BMPR-II and demonstrate that Tctex-1 is phosphorylated by BMPR-II, a function disrupted by PPH disease causing mutations within exon 12. Finally we show that BMPR-II and Tctex-1 co-localize to endothelium and smooth muscle within the media of pulmonary arterioles, key sites of vascular remodelling in PPH. Taken together, these data demonstrate a discrete function for the cytoplasmic domain of BMPR-II and justify further investigation of whether the interaction with and phosphorylation of Tctex-1 contributes to the pathogenesis of PPH

    Analysis and comparison of Scalextric, SCX, and Carrera Digital slot car systems: A mechatronic engineering design case study

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    Digital slot cars operate by transmitting both power and data over a single pair of wires much like DCC-controlled model railways and some home automation systems. In this manuscript we analyse and compare the cars, track, controllers, and electronic data transmission protocols of the three popular digital slot car systems
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