3,933 research outputs found
On the Limiting Vacillating Tableaux for Integer Sequences
A fundamental identity in the representation theory of the partition algeba
is for , where
ranges over integer partitions of , is the number of
standard Young tableaux of shape , and is the number of
vacillating tableaux of shape and length . Using a combination of
RSK insertion and jeu de taquin, Halverson and Lewandowski constructed a
bijection that maps each integer sequence in to a pair
consisting of a standard Young tableau and a vacillating tableau. In this
paper, we show that for a given integer sequence , when is
sufficiently large, the vacillating tableaux determined by
become stable when ; the limit
is called the limiting vacillating tableau for . We give a
characterization of the set of limiting vacillating tableaux and presents
explicit formulas that enumerate those vacillating tableaux
Electric field and tip geometry effects on dielectrophoretic growth of carbon nanotube nanofibrils on scanning probes
Single-wall carbon nanotube (SWNT) nanofibrils were assembled onto a variety
of conductive scanning probes including atomic force microscope (AFM) tips and
scanning tunnelling microscope (STM) needles using positive dielectrophoresis
(DEP). The magnitude of the applied electric field was varied in the range of
1-20 V to investigate its effect on the dimensions of the assembled SWNT
nanofibrils. Both length and diameter grew asymptotically as voltage increased
from 5 to 18 V. Below 4 V, stable attachment of SWNT nanofibrils could not be
achieved due to the relatively weak DEP force versus Brownian motion. At
voltages of 20 V and higher, low quality nanofibrils resulted from
incorporating large amounts of impurities. For intermediate voltages, optimal
nanofibrils were achieved, though pivotal to this assembly is the wetting
behaviour upon tip immersion in the SWNT suspension drop. This process was
monitored in situ to correlate wetting angle and probe geometry (cone angles
and tip height), revealing that probes with narrow cone angles and long shanks
are optimal. It is proposed that this results from less wetting of the probe
apex, and therefore reduces capillary forces and especially force transients
during the nanofibril drawing process. Relatively rigid probes (force constant
>= 2 N/m) exhibited no perceivable cantilever bending upon wetting and
de-wetting, resulting in the most stable process control
Asteroid taxonomic signatures from photometric phase curves
We explore the correlation between an asteroid's taxonomy and photometric
phase curve using the H, G12 photometric phase function, with the shape of the
phase function described by the single parameter G12. We explore the usability
of G12 in taxonomic classification for individual objects, asteroid families,
and dynamical groups. We conclude that the mean values of G12 for the
considered taxonomic complexes are statistically different, and also discuss
the overall shape of the G12 distribution for each taxonomic complex. Based on
the values of G12 for about half a million asteroids, we compute the
probabilities of C, S, and X complex membership for each asteroid. For an
individual asteroid, these probabilities are rather evenly distributed over all
of the complexes, thus preventing meaningful classification. We then present
and discuss the G12 distributions for asteroid families, and predict the
taxonomic complex preponderance for asteroid families given the distribution of
G12 in each family. For certain asteroid families, the probabilistic prediction
of taxonomic complex preponderance can clearly be made. The Nysa-Polana family
shows two distinct regions in the proper element space with different G12
values dominating in each region. We conclude that the G12-based probabilistic
distribution of taxonomic complexes through the main belt agrees with the
general view of C complex asteroid proportion increasing towards the outer
belt. We conclude that the G12 photometric parameter cannot be used in
determining taxonomic complex for individual asteroids, but it can be utilized
in the statistical treatment of asteroid families and different regions of the
main asteroid belt.Comment: submitted to Icaru
Cardiac involvement in hereditary myopathy with early respiratory failure: A cohort study.
OBJECTIVE: To assess whether hereditary myopathy with early respiratory failure (HMERF) due to the c.951434T>C; (p.Cys31712Arg) TTN missense mutation also includes a cardiac phenotype. METHOD: Clinical cohort study of our HMERF cohort using ECG, 2D echocardiogram, and cross-sectional cardiac imaging with MRI or CT. RESULTS: We studied 22 participants with the c.951434T>C; (p.Cys31712Arg) TTN missense mutation. Three were deceased. Cardiac conduction abnormalities were identified in 7/22 (32%): sustained atrioventricular tachycardia (n = 2), atrial fibrillation (n = 2), nonsustained atrial tachycardia (n = 1), premature supraventricular complexes (n = 1), and unexplained sinus bradycardia (n = 1). In addition, 4/22 (18%) had imaging evidence of otherwise unexplained cardiomyopathy. These findings are supported by histopathologic correlation suggestive of myocardial cytoskeletal remodeling. CONCLUSIONS: Coexisting cardiac and skeletal muscle involvement is not uncommon in patients with HMERF arising due to the c.951434T>C; (p.Cys31712Arg) TTN mutation. All patients with pathogenic or putative pathogenic TTN mutations should be offered periodic cardiac surveillance.Wellcome Trust (101876/Z/13/Z, 096919Z/11/Z), Medical Research Council (UK) (G0601943), Medical Research Council Mitochondrial Biology Unit (MC_UP_1501/2).This is the final version of the article. It first appeared from Wolters Kluwer via http://dx.doi.org/10.1212/WNL.000000000000306
VCU Stress Relief: Programs and Tools to Ease Student Stress
Examine how VCU can support students who are having trouble, especially in the freshman year, due to economic challenges their families are facing (parent\u27s loss of jobs, parent\u27s loss of home, students tuition debt, etc). Explore ways to address these issues in the classroom or in individual or group settings
Helping students see eye to eye: Diversifying teaching of sensation and perception in higher education
There is current interest in diversifying teaching curricula across many disciplines in university teaching. Sensation and perception is often considered difficult to diversify. Current challenges include diversity of the topics and teaching tools/materials, and the diversity that characterizes both the student and the teacher populations. We start by describing the diversity present in student and teacher groups, with a UK focus, and discuss how inclusive and diverse teaching materials can impact participation and engagement of broad student groups. We next consider how teaching content can be broadened by teaching on topics that consider differences between participant groups with different characteristics (including gender, ethnicity, disability and culture). Finally, we suggest resources that can be used to diversify sensation and perception teaching. We include example topics where diversity features in perception research, aimed at engaging teachers and students in the process of diversifying the teaching of sensation and perception
Predictive response-relevant clustering of expression data provides insights into disease processes
This article describes and illustrates a novel method of microarray data analysis that couples model-based clustering and binary classification to form clusters of ;response-relevant' genes; that is, genes that are informative when discriminating between the different values of the response. Predictions are subsequently made using an appropriate statistical summary of each gene cluster, which we call the ;meta-covariate' representation of the cluster, in a probit regression model. We first illustrate this method by analysing a leukaemia expression dataset, before focusing closely on the meta-covariate analysis of a renal gene expression dataset in a rat model of salt-sensitive hypertension. We explore the biological insights provided by our analysis of these data. In particular, we identify a highly influential cluster of 13 genes-including three transcription factors (Arntl, Bhlhe41 and Npas2)-that is implicated as being protective against hypertension in response to increased dietary sodium. Functional and canonical pathway analysis of this cluster using Ingenuity Pathway Analysis implicated transcriptional activation and circadian rhythm signalling, respectively. Although we illustrate our method using only expression data, the method is applicable to any high-dimensional datasets
N-body models of globular clusters: metallicity, half-light radii and mass-to-light ratios
Size differences of approx. 20% between red (metal-rich) and blue
(metal-poor) sub-populations of globular clusters have been observed,
generating an ongoing debate as to weather these originate from projection
effects or the difference in metallicity. We present direct N-body simulations
of metal-rich and metal-poor stellar populations evolved to study the effects
of metallicity on cluster evolution. The models start with N = 100000 stars and
include primordial binaries. We also take metallicity dependent stellar
evolution and an external tidal field into account. We find no significant
difference for the half-mass radii of those models, indicating that the
clusters are structurally similar. However, utilizing observational tools to
fit half-light (or effective) radii confirms that metallicity effects related
to stellar evolution combined with dynamical effects such as mass segregation
produce an apparent size difference of 17% on average. The metallicity effect
on the overall cluster luminosity also leads to higher mass-to-light ratios for
metal-rich clusters.Comment: 14 pages, 10 figures, accepted for publication in MNRA
VA residential substance use disorder treatment program providers’ perceptions of facilitators and barriers to performance on pre-admission processes
Abstract Background In the U.S. Department of Veterans Affairs (VA), residential treatment programs are an important part of the continuum of care for patients with a substance use disorder (SUD). However, a limited number of program-specific measures to identify quality gaps in SUD residential programs exist. This study aimed to: (1) Develop metrics for two pre-admission processes: Wait Time and Engagement While Waiting, and (2) Interview program management and staff about program structures and processes that may contribute to performance on these metrics. The first aim sought to supplement the VA’s existing facility-level performance metrics with SUD program-level metrics in order to identify high-value targets for quality improvement. The second aim recognized that not all key processes are reflected in the administrative data, and even when they are, new insight may be gained from viewing these data in the context of day-to-day clinical practice. Methods VA administrative data from fiscal year 2012 were used to calculate pre-admission metrics for 97 programs (63 SUD Residential Rehabilitation Treatment Programs (SUD RRTPs); 34 Mental Health Residential Rehabilitation Treatment Programs (MH RRTPs) with a SUD track). Interviews were then conducted with management and front-line staff to learn what factors may have contributed to high or low performance, relative to the national average for their program type. We hypothesized that speaking directly to residential program staff may reveal innovative practices, areas for improvement, and factors that may explain system-wide variability in performance. Results Average wait time for admission was 16 days (SUD RRTPs: 17 days; MH RRTPs with a SUD track: 11 days), with 60% of Veterans waiting longer than 7 days. For these Veterans, engagement while waiting occurred in an average of 54% of the waiting weeks (range 3–100% across programs). Fifty-nine interviews representing 44 programs revealed factors perceived to potentially impact performance in these domains. Efficient screening processes, effective patient flow, and available beds were perceived to facilitate shorter wait times, while lack of beds, poor staffing levels, and lengths of stay of existing patients were thought to lengthen wait times. Accessible outpatient services, strong patient outreach, and strong encouragement of pre-admission outpatient treatment emerged as facilitators of engagement while waiting; poor staffing levels, socioeconomic barriers, and low patient motivation were viewed as barriers. Conclusions Metrics for pre-admission processes can be helpful for monitoring residential SUD treatment programs. Interviewing program management and staff about drivers of performance metrics can play a complementary role by identifying innovative and other strong practices, as well as high-value targets for quality improvement. Key facilitators of high-performing facilities may offer programs with lower performance useful strategies to improve specific pre-admission processes
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