24 research outputs found
MRT-gesteuerte Radiofrequenz-Ablation in der Behandlung von Lebertumoren : experimentelle und klinische Optimierung
Image-guided radiofrequency ablation of hepatocellular carcinoma (HCC): Is MR guidance more effective than CT guidance?
Liver Lesion Conspicuity During Real-Time MR-Guided Radiofrequency Applicator Placement Using Spoiled Gradient Echo and Balanced Steady-State Free Precession Imaging
Threshold-based prediction of the coagulation zone in sequential temperature mapping in MR-guided radiofrequency ablation of liver tumours
A Comparison of Internally Water-perfused and Cryogenically Cooled Monopolar and Bipolar Radiofrequency Applicators in Ex Vivo Liver Samples
In vitro artifact assessment of an MR-compatible, microwave antenna device for percutaneous tumor ablation with fluoroscopic MRI-sequences
Preclinical evaluation of an MR-compatible microwave ablation system and comparison with a standard microwave ablation system in an ex vivo bovine liver model
Feasibility, efficacy, and safety of percutaneous MR-guided ablation of small (<= 12 mm) hepatic malignancies
Prolonged Antibiotic Prophylaxis in Patients with Bilioenteric Anastomosis Undergoing Percutaneous Radiofrequency Ablation
PURPOSE: To reduce risk of development of a hepatic abscess in patients with preexisting bilioenteric anastomosis (BEA) undergoing radiofrequency (RF) ablation of hepatic tumors by use of prolonged antibiotic prophylaxis over at least 10 days.
MATERIALS AND METHODS: Between April 2003 and June 2011, 184 patients underwent 206 percutaneous RF ablation procedures for hepatic malignancies. Eight patients presented with BEA and were treated in 10 sessions at 14 tumor locations. These 8 patients were male and ranged in age from 55-73 years. Median follow-up was 34 months. Antibiotic prophylaxis was given before the intervention (n = 9, piperacillin/tazobactam; n = 1, ciprofloxacin). Oral antibiotic prophylaxis after the intervention was continued with ciprofloxacin for at least 10 days. In four cases, prophylaxis after the intervention was extended with additional antibiotics.
RESULTS: A liver abscess occurred 22 days after 1 of 10 RF ablation sessions in patients with preexisting BEA. The patient who developed an abscess presented with a large hepatocellular carcinoma (59 mm × 54 mm) and underwent transarterial chemoembolization 8 days before RF ablation. No hepatic abscess occurred after 196 RF ablation sessions in 176 patients without BEA.
CONCLUSIONS: Preexisting BEA is a risk factor for formation of hepatic abscesses after RF ablation. An antibiotic prophylaxis regimen before the intervention and for a prolonged period after the intervention that covers anaerobic bacteria for at least 10 days is presented. Combined therapy of transarterial chemoembolization and RF ablation increases the risk for complications in patients with known BEA