2,956 research outputs found

    Die Unterfamilie der Halacaridae MURR - und die Meeresmilben der Ostsee

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    Lebenslauf."Alphabetisches Verzeichniss der citirten Abhandlungen" : p. [137]-140.Inaug.-diss. - Kiel.Mode of access: Internet

    At tænke teater, turde tage chancer og ikke stole på formler: – et blik på dramaturgiens aktuelle position og uddannelsens muligheder

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    The German professor of Theatre Studies argues for the necessity of educating dramaturgs with an open mind towards contemporary art and culture. Likewise he emphasizes the need for having the courage to experiment with new forms of expression and working methods

    Automatic Verification of Application-Tailored OSEK Kernels

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    The OSEK industrial standard governs the design of embedded real-time operating systems in the automotive domain. We report on efforts to develop verification methods for OSEK-conformant compilers, specifically of a code generator that weaves system calls and application code using a static configuration file, producing a stand-alone application that incorporates the relevant parts of the kernel. Our methodology involves two verification steps: On the one hand, we extract an OS-application interaction graph during the compilation phase and verify that it conforms to the standard, in particular regarding prioritized scheduling and interrupt handling. To this end, we generate from the configuration file a temporal specification of standard-conformant behaviour and model check the arising formulas on a labelled transition system extracted from the interaction graph. On the other hand, we verify that the actual generated code conforms to the interaction graph; this is done by graph isomorphism checking of the interaction graph against a dynamically-explored state-transition graph of the generated system

    Psychosocial impact of prognostic genetic testing in the care of uveal melanoma patients: protocol of a controlled prospective clinical observational study

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    Background: Uveal melanoma patients with a poor prognosis can be detected through genetic analysis of the tumor, which has a very high sensitivity. A large number of patients with uveal melanoma decide to receive information about their individual risk and therefore routine prognostic genetic testing is being carried out on a growing number of patients. It is obvious that a positive prediction for recidivism in the future will emotionally burden the respective patients, but research on the psychosocial impact of this innovative method is lacking. The aim of the current study is therefore to investigate the psychosocial impact (psychological distress and quality of life) of prognostic genetic testing in patients with uveal melanoma. Design and methods: This study is a non-randomized controlled prospective clinical observational trial. Subjects are patients with uveal melanoma, in whom genetic testing is possible. Patients who consent to genetic testing are allocated to the intervention group and patients who refuse genetic testing form the observational group. Both groups receive cancer therapy and psycho-oncological intervention when needed. The psychosocial impact of prognostic testing is investigated with the following variables: resilience, social support, fear of tumor progression, depression, general distress, cancer-specific and general health-related quality of life, attitude towards genetic testing, estimation of the perceived risk of metastasis, utilization and satisfaction with psycho-oncological crisis intervention, and sociodemographic data. Data are assessed preoperatively (at initial admission in the clinic) and postoperatively (at discharge from hospital after surgery, 6–12 weeks, 6 and 12 months after initial admission). Genetic test results are communicated 6–12 weeks after initial admission to the clinic. Discussion: We created optimal conditions for investigation of the psychosocial impact of prognostic genetic testing. This study will provide information on the course of disease and psychosocial outcomes after prognostic genetic testing. We expect that empirical data from our study will give a scientific basis for medico-ethical considerations

    GlĂĽcklich in Wuppertal - ein urbanes Wohlbefindens-Panel

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    Das FGW-geförderte Projekt 'Glücklich in Wuppertal' hat die erste Phase in der Einrichtung des weltweit ersten appbasierten urbanen Wohlbefindens-Panels ermöglicht. Mit einer Smartphone-App wird hier sowohl Glücksforschung systematisch auf die urbane Ebene gebracht als auch ein neues Instrument für Partizipation in der Stadt geschaffen. Basierend auf der Infrastruktur und Vorarbeiten der Happiness Research Organisation (HRO) und eingebettet in Arbeiten des Wuppertal Instituts zu neuen Wohlstandsmodellen erfasst die App in mehreren sich ergänzenden Modulen das subjektive und kommunale Wohlbefinden der Wuppertaler Bevölkerung. Über die Projektlaufzeit von 12 Monaten wurde der zentrale Fragebogen 1799-mal voll verwertbar von unterschiedlichen Personen ausgefüllt. Über eine sehr starke Medienpräsenz und sonstige Kommunikationsmaßnahmen konnte gemeinsam mit lokalen Partner_innen ein hoher Bekanntheitsgrad der App erreicht werden. Erste Einbindungen der Ergebnisse in städtische Entwicklungsprozesse laufen und werden aktuell erweitert.The Project 'Happy in Wuppertal' included the first phase of establishing the world’s first urban app-based well-being panel. With an app for smartphones research on well-being and happiness is being brought to the city level. Beyond research, the app will become a new tool for participation in the City of Wuppertal. The project uses existing work and infrastructure of the Happiness Research Organization (HRO) that has been implemented in various international projects. It is also based on work at the Wuppertal Institute on new forms of wealth and well-being. The app consists of several complementing modules that look into the personal and communal well-being of the citizens of Wuppertal. Within 12 months the central questionnaire has been answered 1799 times in full by different individuals. The app is very well known within the city due to partnerships with local enterprises and media. Some first steps towards using the app in decision making have been taken and will be extended

    Eine neue Form der BĂĽrgerbeteiligung: das Beispiel der App 'GlĂĽcklich in Wuppertal'

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    Smartphone-Apps ermöglichen eine niedrigschwellige und regelmäßige Kommunikation zwischen Bürgern und kommunaler Verwaltung. Sie können damit die Mängel 'analoger' Formen der Bürgerbeteiligung ausgleichen und fördern eine partizipative Stadtentwicklung. Die App kann in städtische Entwicklungsprozesse eingebunden werden, um mehr Menschen die Möglichkeit zur Partizipation zu geben. In Wuppertal geschieht dies bereits. Zentrale Erfolgsfaktoren sind ein intuitives Interface, ein deutlicher Mehrwert für die Nutzer_innen, Öffentlichkeitsarbeit, lokale Partner_innen und ein zeitnahes Feedback aus Politik und Verwaltung. Breit angelegte Erhebungen können zeigen, wie Luftqualität, Arbeitsplätze und städtische Infrastrukturen von Bürger_innen wahrgenommen werden und welche Faktoren dazu führen, dass Stadtteile 'glücklich machen'

    Can tree-ring density data reflect summer temperature extremes and associated circulation patterns over Fennoscandia?

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    Tree-ring maximum latewood density (MXD) records from Fennoscandia have been widely used to infer regional- and hemispheric-scale mean temperature variability. Here, we explore if MXD records can also be used to infer past variability of summer temperature extremes across Fennoscandia. The first principal component (PC1) based on 34 MXD chronologies in Fennoscandia explains 50% of the total variance in the observed warm-day extremes over the period 1901–1978. Variations in both observed summer warm-day extremes and PC1 are influenced by the frequency of anomalous anticyclonic pattern over the region, summer sea surface temperatures over the Baltic, North and Norwegian Seas, and the strength of the westerly zonal wind at 200 hPa across Fennoscandia. Both time series are associated with nearly identical atmospheric circulation and SST patterns according to composite map analysis. In a longer context, the first PC based on 3 millennium-long MXD chronologies in central and northern Fennoscandia explains 83% of the total variance of PC1 from the 34 MXD chronologies over the period 1901–1978, 48% of the total variance of the summer warm-day extreme variability over the period 1901–2006, and 36% of the total variance in the frequency of a summer anticyclonic pattern centered over eastern-central Fennoscandia in the period 1948–2006. The frequency of summer warm-day extremes in Fennoscandia is likely linked to a meridional shift of the northern mid-latitude jet stream. This study shows that the MXD network can be used to infer the variability of past summer warm-day extremes and the frequency of the associated summer anticyclonic circulation pattern over Fennoscandia

    Fast Beam Condition Monitor for CMS: performance and upgrade

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    The CMS beam and radiation monitoring subsystem BCM1F (Fast Beam Condition Monitor) consists of 8 individual diamond sensors situated around the beam pipe within the pixel detector volume, for the purpose of fast bunch-by-bunch monitoring of beam background and collision products. In addition, effort is ongoing to use BCM1F as an online luminosity monitor. BCM1F will be running whenever there is beam in LHC, and its data acquisition is independent from the data acquisition of the CMS detector, hence it delivers luminosity even when CMS is not taking data. A report is given on the performance of BCM1F during LHC run I, including results of the van der Meer scan and on-line luminosity monitoring done in 2012. In order to match the requirements due to higher luminosity and 25 ns bunch spacing, several changes to the system must be implemented during the upcoming shutdown, including upgraded electronics and precise gain monitoring. First results from Run II preparation are shown.Comment: 10 pages, 8 figures. To be published in NIM A as proceedings for the 9th Hiroshima Symposium on Semiconductor Tracking Detectors (2013
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