You Don’t Know My Story : Engaging Black Parents with Culturally Responsive School Practices

Black parents have reported feeling alienated from their children’s schooling experiences, citing weak school communications, challenges with trust, and teachers’ misperceived values of parents (Brandon, Higgins, Pierce, Tandy, & Sileo, 2010). Drawing from the tenets of critical race theory of education (Ladson-Billings & Tate, 1995) and culturally responsive teaching (Ladson-Billings, 1994; Villegas & Lucas, 2002), the purpose of this study was to better understand the qualities within schools that parents experience as welcoming their participation and influencing their motivation to maintain involvement. By privileging the voices of nine Black parents using one-time, semi-structured interviews, this study began to define what culturally responsive school practices mean for Black parents. Parents reported three overarching ways schools affirm them and engage their cultural ways of being: 1) schools that have diverse leaders and teachers; 2) schools that integrate Black culture in their curricula and school culture; and, 3) schools that value parent voices in decision making. Recommendations are offered for school leaders and teachers for sustainable and culturally-responsive strategies for Black parent engagement

Black and Latino Fathers of Students With Autism: Culturally Responsive Support

Perspectives from five Black and Latino fathers of students with autism are shared from this qualitative pilot study. The fathers were asked to describe the most helpful forms of support from school counselors. One-time, semi-structured interviews were conducted and interpreted with the thematic analysis method. Results suggest support from other parents, and specifically from other fathers, with shared experiences is most helpful. Recommendations for school counseling practice and research are shared

Iron(II) supramolecular helicates interfere with the HIV-1 Tat–TAR RNA interaction critical for viral replication

The interaction between the HIV-1 transactivator protein Tat and TAR (transactivation responsive region) RNA, plays a critical role in HIV-1 transcription. Iron(II) supramolecular helicates were evaluated for their in vitro activity to inhibit Tat–TAR RNA interaction using UV melting studies, electrophoretic mobility shift assay, and RNase A footprinting. The results demonstrate that iron(II) supramolecular helicates inhibit Tat-TAR interaction at nanomolar concentrations by binding to TAR RNA. These studies provide a new insight into the biological potential of metallosupramolecular helicates

Twigraph: Discovering and Visualizing Influential Words between Twitter Profiles

The social media craze is on an ever increasing spree, and people are connected with each other like never before, but these vast connections are visually unexplored. We propose a methodology Twigraph to explore the connections between persons using their Twitter profiles. First, we propose a hybrid approach of recommending social media profiles, articles, and advertisements to a user.The profiles are recommended based on the similarity score between the user profile, and profile under evaluation. The similarity between a set of profiles is investigated by finding the top influential words thus causing a high similarity through an Influence Term Metric for each word. Then, we group profiles of various domains such as politics, sports, and entertainment based on the similarity score through a novel clustering algorithm. The connectivity between profiles is envisaged using word graphs that help in finding the words that connect a set of profiles and the profiles that are connected to a word. Finally, we analyze the top influential words over a set of profiles through clustering by finding the similarity of that profiles enabling to break down a Twitter profile with a lot of followers to fine level word connections using word graphs. The proposed method was implemented on datasets comprising 1.1 M Tweets obtained from Twitter. Experimental results show that the resultant influential words were highly representative of the relationship between two profiles or a set of profile

Benchmarking of 3D space charge codes using direct phase space measurements from photoemission high voltage DC gun

We present a comparison between space charge calculations and direct measurements of the transverse phase space for space charge dominated electron bunches after a high voltage photoemission DC gun followed by an emittance compensation solenoid magnet. The measurements were performed using a double-slit setup for a set of parameters such as charge per bunch and the solenoid current. The data is compared with detailed simulations using 3D space charge codes GPT and Parmela3D with initial particle distributions created from the measured transverse and temporal laser profiles. Beam brightness as a function of beam fraction is calculated for the measured phase space maps and found to approach the theoretical maximum set by the thermal energy and accelerating field at the photocathode.Comment: 11 pages, 23 figures. submitted to Phys Rev ST-A

Key Nutritional Considerations for Youth Winter Sports Athletes to Optimize Growth, Maturation and Sporting Development.

Despite a wealth of sport nutrition guidelines for adult athletes, there are currently no nutrition guidelines for youth winter sports athletes. Whilst it may be pragmatic to apply nutrition guidelines for adult athletes to youth winter sports athletes, it is inappropriate. Due to a paucity of research on youth athletes, it is impossible to provide evidence-based guidelines for this population, so careful extrapolation from the theoretical and practical considerations that apply to other athletic groups is necessary. Youth winter sport athletes undergo rapid biological growth and maturation which influences their nutritional requirements. A varied and balanced diet that ensures sufficient energy availability for optimal growth and maturation as well as sporting performance is the cornerstone of youth athlete nutrition and should also allow for youth athletes to meet their micronutrient requirements. In some cases, micronutrient status (e.g., vitamin D and iron) should be monitored and optimized if appropriate by a medical professional. Dietary supplement use is prevalent amongst youth athletes, however is often unnecessary. Education of youth athletes, their parents and coaches on best nutritional practices as well as the risks associated with dietary supplements is vital for their long-term athletic development. Further research in youth winter sports athletes across different stages of growth and maturation competing in a variety of sports is urgently required in order to inform nutritional guidelines for this population

RNF17 blocks promiscuous activity of PIWI proteins in mouse testes

PIWI proteins and their associated piRNAs protect germ cells from the activity of mobile genetic elements. Two classes of piRNAs-primary and secondary-are defined by their mechanisms of biogenesis. Primary piRNAs are processed directly from transcripts of piRNA cluster loci, whereas secondary piRNAs are generated in an adaptive amplification loop, termed the ping-pong cycle. In mammals, piRNA populations are dynamic, shifting as male germ cells develop. Embryonic piRNAs consist of both primary and secondary species and are mainly directed toward transposons. In meiotic cells, the piRNA population is transposon-poor and largely restricted to primary piRNAs derived from pachytene piRNA clusters. The transition from the embryonic to the adult piRNA pathway is not well understood. Here we show that RNF17 shapes adult meiotic piRNA content by suppressing the production of secondary piRNAs. In the absence of RNF17, ping-pong occurs inappropriately in meiotic cells. Ping-pong initiates piRNA responses against not only transposons but also protein-coding genes and long noncoding RNAs, including genes essential for germ cell development. Thus, the sterility of Rnf17 mutants may be a manifestation of a small RNA-based autoimmune reaction

Retinopathy predicts progression of fasting plasma glucose: An Early Diabetes Intervention Program (EDIP) analysis

Background Retinopathy is increasingly recognized in prediabetic populations, and may herald increased risk of metabolic worsening. The Early Diabetes Intervention Program (EDIP) evaluated worsening of glycemia in screen-detected Type 2 diabetes, following participants for up to 5 years. Here we have evaluated whether the presence of retinopathy at the time of detection of diabetes was associated with accelerated progression of glycemia. Methods We prospectively studied 194 participants from EDIP with available baseline retinal photographs. Retinopathy was determined at baseline using 7-field fundus photography and defined as an Early Treatment of Diabetic Retinopathy Study Scale grading score of ≥ 20. Results At baseline, 12% of participants had classical retinal lesions indicating retinopathy. In univariate Cox proportional hazard analysis, the presence of retinopathy at baseline was associated with a doubled risk of progression of fasting plasma glucose (HR 2.02; 95% CI 1.05–3.89). The retinopathy effect was robust to individual adjustment for age and glucose, the most potent determinants of progression in EDIP. Conclusion Retinopathy was associated with increased risk of progression of fasting plasma glucose among adults with screen-detected, early diabetes. Early detection of retinopathy may help individualize more aggressive therapy to prevent progressive metabolic worsening in early diabetes