Britain's first computer centre for banking: What did this building do?

At the beginning of the 1960s Barclays became the first British bank to open a computer centre. In this paper I trace the life of this building starting with its official opening on 4 July 1961 and ending with its protracted closure a decade later. From initial status as the most advanced bank bookkeeping system in the world serving as a highly visible symbol of the bank's technological power, to a final repurposing of its grandiose reception as a distribution point for pre- and post-decimalisation output, the building's various meanings are revealed. Making use of written, oral, and visual sources I explore the centre's spatial characteristics, its relation to the distributed structure of the branch, and its place as a first dedicated working home for a newly emerging computing subculture. A blend of multiple perspectives internally from the top down and bottom up, and externally from customer and competitor, offer an analysis that uncovers the part played by the first computer centre place in the banking automation race

An Honorable Journey

A history of Liberty University\u27s Honors Program

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland

We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs. We proposed that growth hormone (GH) increases the survival factor IGF-I, whilst prolactin (PRL) enhances the effects of GH by decreasing the concentration of IGFBP-5, which would otherwise inhibit the actions of IGFs. To demonstrate a causal relationship between IGFBP-5 and cell death, we created transgenic mice expressing IGFBP-5, specifically, in the mammary gland. DNA content in the mammary glands of transgenic mice was decreased as early as day 10 of pregnancy. Mammary cell number and milk synthesis were both decreased by approximately 50% during the first 10 days of lactation. The concentrations of the pro-apoptotic molecule caspase-3 was increased in transgenic animals whilst the concentrations of two pro-survival molecules Bcl-2 and Bcl-x were both decreased. In order to examine whether IGFBP-5 acts by inhibiting the survival effect of IGF-I, we examined IGF receptor- and Akt-phoshorylation and showed that both were inhibited. These studies also indicated that the effects of IGFBP-5 could be mediated in part by IGF-independent effects involving potential interactions with components of the extracellular matrix involved in tissue remodeling, such as components of the plasminogen system, and the matrix metallo-proteinases (MMPs). Mammary development was normalised in transgenic mice by R3-IGF-I, an analogue of IGF-I which binds weakly to IGFBPs, although milk production was only partially restored. In contrast, treatment with prolactin was able to inhibit early involutionary processes in normal mice but was unable to prevent this in mice over-expressing IGFBP-5, although it was able to inhibit activation of MMPs. Thus, IGFBP-5 can simultaneously inhibit IGF action and activate the plasminogen system thereby coordinating cell death and tissue remodeling processes. The ability to separate these properties, using mutant IGFBPs, is currently under investigatio

Sentencing as craftwork and the binary epistemologies of the discretionary decision process

This article contends that it is time to take a critical look at a series of binary categories which have dominated the scholarly and reform epistemologies of the sentencing decision process. These binaries are: rules versus discretion; reason versus emotion; offence versus offender; normative principles versus incoherence; aggravating versus mitigating factors; and aggregate/tariff consistency versus individualized sentencing. These binaries underpin both the 'legal-rational' tradition (by which I mean a view of discretion as inherently suspect, a preference for the use of philosophy of punishment justifications and an explanation of the decision process through factors or variables), and also the more recent rise of the 'new penology'. Both approaches tend to rely on 'top-down' assumptions of change, which pay limited attention to the agency of penal workers. The article seeks to develop a conception of sentencing craftwork as a social and interpretive process.1 In so doing, it applies and develops a number of Kritzer's observations (in this issue) about craftwork to sentencing. These craftwork observations are: problem solving (applied to the rules - discretion and reason - emotion dichotomies); skills and techniques (normative penal principles and the use of cognitive analytical assumptions); consistency (tariff versus individualized sentencing); clientele (applied to account giving and the reality of decision making versus expression). By conceiving of sentencing as craftwork, the binary epistemologies of the sentencing decision process, which have dominated (and limited) the scholarly and policy sentencing imaginations, are revealed as dynamic, contingent, and synergistic. However, this is not to say that such binaries are no more than empty rhetoric concealing the reality of the decision process. Rather, these binaries serve as crucial legitimating reference points in the vocabulary of sentencing account giving

The Cowl - v.28 - n.21 - Nov 19, 1975

The Cowl - student newspaper of Providence College. Volume 28, Number 21 - November 19, 1975. 8 pages. Note: The volume number printed on the banner page of this issue (XXVIII) duplicates the volume number for 1965-66 academic year

Rahul Sankrityayan, Tsetan Phuntsog and Tibetan Textbooks for Ladakh in 1933

In 1933 the Indian scholar and social activist Rahul Sankrityayan (1893-1963) compiled a set of four Tibetan-language readers and a grammar for use in Ladakhi schools, together with his Ladakhi colleague Tsetan Phuntsog. The readers contain a mix of material from Western, Indian, Ladakhi and Tibetan sources. This includes simple essays about ‘air’ and ‘water’, selections from Aesop’s fables, Indian folk stories, biographies of famous people in Ladakhi and Tibetan history, poems by Ladakhi authors, and extracts from the Treasury of Elegant Sayings by Sakya Pandita Kunga Gyaltsen (1182-1251). This essay begins with a review of earlier Tibetan-language schoolbooks published in British India, and then discusses the circumstances that led to Sankrityayan’s involvement in the Ladakh project. The second part of the essay examines the contents of the readers and the grammar, including—where possible—the authorship of particular sections. Finally, the essay briefly reviews linguistic developments in Ladakh since the publication of the textbooks

Conservation and crime convergence? Situating the 2018 London Illegal Wildlife Trade Conference

The 2018 London Illegal Wildlife Trade (IWT) Conference was the fourth and biggest meeting on IWT convened at the initiative of the UK Government. Using a collaborative event ethnography, we examine the Conference as a site where key actors defined the problem of IWT as one of serious crime that needs to be addressed as such. We ask (a) how was IWT framed as serious crime, (b) how was this framing mobilized to promote particular policy responses, and (c) how did the framing and suggested responses reflect the privileging of elite voices? Answering these questions demonstrates the expanding ways in which thinking related to crime and policing are an increasingly forceful dynamic shaping conservation-related policy at the global level. We argue that the conservation-crime convergence on display at the 2018 London IWT Conference is characteristic of a conservation policy landscape that increasingly promotes and privileges responses to IWT that are based on legal and judicial reform, criminal investigations, intelligence gathering, and law enforcement technologies. Marginalized are those voices that seek to address the underlying drivers of IWT by promoting solutions rooted in sustainable livelihoods in source countries and global demand reduction. We suggest that political ecology of conservation and environmental crime would benefit from greater engagement with critical criminology, a discipline that critically interrogates the uneven power dynamics that shape ideas of crime, criminality, how they are politicized, and how they frame policy decisions. This would add further conceptual rigor to political ecological work that deconstructs conservation and environmental crime