98 research outputs found
Validity of two common asthma-specific quality of life questionnaires: Juniper mini asthma quality of life questionnaire and Sydney asthma quality of life questionnaire
Background
This study explored the psychometric properties (internal consistency, construct validity, discriminative ability) of the Juniper Mini Asthma Quality of Life Questionnaire (Mini AQLQ-J) and the Sydney Asthma Quality of Life Questionnaire (AQLQ-S).
Methods
One hundred fourty-six adults (18-45 years) with asthma requiring regular inhaled corticosteroids were recruited to a trial of written emotional disclosure. Correlational analyses were performed to understand the relationship of the two measures with each other, with symptoms, lung function, asthma control, asthma bother and generic quality of life. Median quality of life scores were compared according to gender, health care usage and levels of asthma severity.
Results
AQLQ-J and AQLQ-S total scores correlated strongly with each other (rho = -0.80) and moderately with the EuroQol Current Health Status Scale (AQLQ-J: rho = 0.35; AQLQ-S: rho = -0.40). Domain score correlations between AQLQ-J and AQLQ-S were mostly moderate (0.5 < rho < 0.8). Both QoL measures were significantly correlated with symptom score. Correlations with the symptom score asthma module (AQLQ-J: rho = -0.69; AQLQ-S: rho = 0.50) were stronger compared with the total symptom score and the symptom score rhinitis module (AQLQ-J: rho = -0.41; AQLQ-M: rho =0.31). Neither QoL measure was significantly correlated with FEV1 % predicted at the total or the domain level. Total scores of both measures were significantly correlated with subjective asthma control (AQLQ-J: rho = 0.68; AQLQ-S: rho = -0.61) and asthma bother (AQLQ-J: rho = -0.73; AQLQ-M: rho = 0.73).
Conclusions
This study provides further evidence for the validity of the AQLQ-J and the AQLQ-S in a British population of adult patients with asthma managed in primary care. Correlations with lung function parameters were weak or absent. Correlations with generic quality of life were moderate, those with asthma symptoms, asthma control and asthma bother were strong. Both measures are able to discriminate between levels of asthma severity
An Infrared Study of the Circumstellar Material Associated with the Carbon Star R Sculptoris
The asymptotic giant branch (AGB) star R Sculptoris (R Scl) is one of the
most extensively studied stars on the AGB. R Scl is a carbon star with a
massive circumstellar shell () which
is thought to have been produced during a thermal pulse event years
ago. To study the thermal dust emission associated with its circumstellar
material, observations were taken with the Faint Object InfraRed CAMera for the
SOFIA Telescope (FORCAST) at 19.7, 25.2, 31.5, 34.8, and 37.1 m. Maps of
the infrared emission at these wavelengths were used to study the morphology
and temperature structure of the spatially extended dust emission. Using the
radiative transfer code DUSTY and fitting the spatial profile of the emission,
we find that a geometrically thin dust shell cannot reproduce the observed
spatially resolved emission. Instead, a second dust component in addition to
the shell is needed to reproduce the observed emission. This component, which
lies interior to the dust shell, traces the circumstellar envelope of R Scl. It
is best fit by a density profile with where
and dust mass of
. The strong departure from an
law indicates that the mass-loss rate of R Scl has not been constant.
This result is consistent with a slow decline in the post-pulse mass-loss which
has been inferred from observations of the molecular gas.Comment: 10 pages, 10 figures, accepted to Ap
Change in anxiety following successful and unsuccessful attempts at smoking cessation: cohort study
Background Despite a lack of empirical evidence, many smokers and health professionals believe that tobacco smoking reduces anxiety, which may deter smoking cessation. Aims The study aim was to assess whether successful smoking cessation or relapse to smoking after a quit attempt are associated with changes in anxiety. Method A total of 491 smokers attending National Health Service smoking cessation clinics in England were followed up 6 months after enrolment in a trial of pharmacogenetic tailoring of nicotine replacement therapy (ISRCTN14352545). Results There was a points difference of 11.8 (95% CI 7.7-16.0) in anxiety score 6 months after cessation between people who relapsed to smoking and people who attained abstinence. This reflected a three-point increase in anxiety from baseline for participants who relapsed and a nine-point decrease for participants who abstained. The increase in anxiety in those who relapsed was largest for those with a current diagnosis of psychiatric disorder and whose main reason for smoking was to cope with stress. The decrease in anxiety on abstinence was larger for these groups also. Conclusions People who achieve abstinence experience a marked reduction in anxiety whereas those who fail to quit experience a modest increase in the long term. These data contradict the assumption that smoking is a stress reliever, but suggest that failure of a quit attempt may generate anxiety
Modeling the Multiwavelength Evolution of the V960 Mon System
We study the evolution of the FU Ori object V960 Mon since its outburst,
using available multi-wavelength photometric time series over 8 years,
complemented by several epochs of moderate-dispersion spectrophotometry. We
find that the source fading can be well-described by a decrease in the
temperature of the inner disk, which results from a combination of decreasing
accretion rate and increasing inner disk radius. We model the system with a
disk atmosphere model that produces the observed variations in multi-band
photometry (this paper) and high resolution spectral lines (a companion paper).Comment: 15 pages, 13 figures, 2 tables, Accepted to Ap
Resolving Decades of Periodic Spirals from the Wolf-Rayet Dust Factory WR 112
WR 112 is a dust-forming carbon-rich Wolf-Rayet (WC) binary with a dusty
circumstellar nebula that exhibits a complex asymmetric morphology, which
traces the orbital motion and dust formation in the colliding winds of the
central binary. Unraveling the complicated circumstellar dust emission around
WR 112 therefore provides an opportunity to understand the dust formation
process in colliding-wind WC binaries. In this work, we present a multi-epoch
analysis of the circumstellar dust around WR 112 using seven high spatial
resolution (FWHM ) N-band ( m) imaging
observations spanning almost 20 years and includes newly obtained images from
Subaru/COMICS in Oct 2019. In contrast to previous interpretations of a face-on
spiral morphology, we observe clear evidence of proper motion of the
circumstellar dust around WR 112 consistent with a nearly edge-on spiral with a
half-opening angle and a -yr period. The revised
near edge-on geometry of WR 112 reconciles previous observations of highly
variable non-thermal radio emission that was inconsistent with a face-on
geometry. We estimate a revised distance to WR 112 of kpc based on the observed dust expansion rate and a
spectroscopically derived WC terminal wind velocity of
km s. With the newly derived WR 112 parameters we fit optically-thin
dust spectral energy distribution models and determine a dust production rate
of M yr, which
demonstrates that WR 112 is one of the most prolific dust-making WC systems
known.Comment: 17 pages, 9 figures, 1 animated gif, accepted for publication in Ap
Resolving Decades of Periodic Spirals from the Wolf–Rayet Dust Factory WR 112
WR 112 is a dust-forming carbon-rich Wolf–Rayet (WC) binary with a dusty circumstellar nebula that exhibits a complex asymmetric morphology, which traces the orbital motion and dust formation in the colliding winds of the central binary. Unraveling the complicated circumstellar dust emission around WR 112 therefore provides an opportunity to understand the dust formation process in colliding-wind WC binaries. In this work, we present a multi-epoch analysis of the circumstellar dust around WR 112 using seven high spatial resolution (FWHM ~ 0farcs3–0farcs4) N-band (λ ~ 12 μm) imaging observations spanning almost 20 yr and that includes images obtained from Subaru/COMICS in 2019 October. In contrast to previous interpretations of a face-on spiral morphology, we observe clear evidence of proper motion of the circumstellar dust around WR 112 consistent with a nearly edge-on spiral with a θ_s = 55° half-opening angle and a ~20 yr period. The revised near edge-on geometry of WR 112 reconciles previous observations of highly variable nonthermal radio emission that was inconsistent with a face-on geometry. We estimate a revised distance to WR 112 of d = 3.39_(-0.84)^(+0.89) kpc based on the observed dust expansion rate and a spectroscopically derived WC terminal wind velocity of v_∞ = 1230 ± 260 km s⁻¹. With the newly derived WR 112 parameters, we fit optically thin dust spectral energy distribution models and determine a dust production rate of Ṁ_d = 2.7_(-1.3)^(+1.0) x 10⁻⁶ M_⊙ yr⁻¹, which demonstrates that WR 112 is one of the most prolific dust-making WC systems known
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