Frequency and Causes of Pediatric Ovarian Torsion: A Systematic Review

Objective: The aim of my study was to determine the frequency and causes of pediatric ovarian torsion. Background: The condition in which an ovary twist along the ligament which hold it in place is known as Ovarian Torsion. The blood flow to ovary and fallopian tube could be cut off because of this twisting. ovarian torsion cab be a cause of unbearable pain due to lack of sufficient blood that should be received by ovary. On behalf of this systematic review, I wanted to dictate the frequency and causes of pediatric ovarian torsion. On the basis of past studies, I reviewed ovarian torsion can be happen at any paediatric age (infant to eighteen years). Around fifty-two % of the cases in children happen between nine years to fourteen years of age, with a median of age 11. Method: An electric database search was performed (google scholar, PubMed and science direct) with time limit until January 2020. All studies, fully available in English, assessing the frequency and causes of pediatric ovarian torsion. Study design: Systematic review-based design is used for this study. Results: 16 articles were reviewed, I found that frequency of pediatric ovarian torsion were rare and happened at any pediatric age. Ovarian torsion was caused by benign lesion, malignancy or by normal ovary. Purpose: The aim of my study was to determine the frequency and causes of pediatric ovarian torsion. Keywords: Ovarian torsion, oophorectomy, neoplasm, malignancy. DOI: 10.7176/JHMN/90-15 Publication date:June 30th 202

Relationship of Type II Diabetes Mellitus in Women with Polycystic Ovarian Syndrome: A Systematic Review

Objective: The purpose of my study was to determine the relationship of Type 2  diabetes mellitus in women with PCOS. Background: PCOS is a hormonal disorder affecting millions of women around the world. 1 in every 10 women have PCOS but many women go years before receiving the diagnosis. In fact it is estimated that 70% of PCOS cases have a root cause is insulin resistance, A major risk factor for Type 2 diabetes mellitus. More than half of women with PCOS develop type 2 diabetes. PCOS is linked with higher levels of circulating insulin, which is characteristic in type 2 diabetes. IR is the typical condition of subjects with T2D. Women with PCOS share with people with T2D the same impaired glucose pattern consisting of a prevalent disturbance of fasting blood glucose. Higher levels of IR stress the pancreatic beta cell function, resulting in earlier functional depletion of insulin secretion capacity and higher risk of developing T2D. In this Systematic review I wanted to determine the incidence of type 2 diabetes in women with PCOS. According to the studies that I reviewed women with PCOS have a markedly increased risk of developing type 2 diabetes then women without PCOS and there is a higher prevalence of PCOS in those women who have Type 2 diabetes mellitus rather than non-diabetic. Method:An electric database search was performed (google scholar, PubMed and science direct)  without time limit until january 2020. All studies, fully available in English, assessing the incidence Type II Diabetes Mellitus in Women with PCOS.  Study design: Systematic review.  Results:I reviewed 22 articles and found that there were high risk of Diabetes Mellitus Type 2 in PCOS females then other one. Middle aged women with PCOS were having elevated risk of Type 2 Diabetes Mellitus, So therefore it propped up the needs of PCOS for routine screening of diabetes. The information or data from articles likewise gave furthur clinical bits of knowledge on the side of focusing on BMI (Body Mass Index), glucose (fasting glucose and after glucose ingestion) and in risk stratification and intervention for glucose homeostasis maintenance. Keywords: Polycystic Ovarian Disease, Type II Diabetes Mellitus, Insulin Resistance DOI: 10.7176/JHMN/90-13 Publication date:June 30th 202

Evaluation of Cervical Disc Degeneration in Patients with Neck Pain on Magnetic Resonance Imaging

Background: Cervical disc degeneration is the most common pathology that in most of the cases  clinically present as Objective: To evaluate the cervical region abnormalities in patients with neck pain on magnetic resonance imaging. Methodology: In this descriptive study 180 adult patients were included. All patients had been collected from DHQ hospital Gilgit and Ghurki Trust teaching hospital. After informed consent, data were collected through 1.5 tesla GE (closed bore) and 0.35 tesla Hitachi (open bore) MRI machines. Results:  Findings show that among 180 adult patients, 136 presented with disc degeneration among which 81 were males and 55 were females. Among 81 males, 63 had disc degeneration at multiple levels while 18 had single disc degeneration. In females 35 patients showed multiple disc degeneration while 20 involved a single disc. Conclusion: It is concluded that disc degeneration is prevalent in males than females. Disc degeneration at multiple levels is higher than single disc degeneration in both genders. Keywords: Disc degeneration, magnetic resonance imaging. DOI: 10.7176/JHMN/99-03 Publication date: April 30th 2022

Sonographic Evaluation of Cholelithiasis and Its Correlation with Normal/Fatty Liver

Cholelithiasis and Fatty Liver disease are usually observed to coexist. Patients who have gallstones also have Fatty Liver as both of the conditions have same associated risk factors I.e., diabetes mellitus, gender, age, obesity, metabolic syndrome, insulin resistance and high lipids level. Non-Alcoholic Fatty Liver Disease (NAFLD) is also an independent accountable risk factor for the formation of gallstones. We aimed to determine whether there is any correlation between cholelithiasis and fatty liver disease. The study was conducted in Lahore General Hospital, Lahore, Pakistan. The data was collected from March 24,2021 to May 24,2021. Informed consent was taken from all the participants. We did a cohort study comprising the data of 51 patients undergoing physical checkup. The data gathered included age, gender and whether they had normal or fatty liver. Cholelithiasis was diagnosed by confirming the presence of gallstones on abdominal ultrasonography after fasting for approximately 8hrs. it was an observational study for the assessment of correlation between cholelithiasis and fatty liver in the participants. A Total of 51 patients with cholelithiasis were included in our study. Most of the patients were 29 to 70 years of age. The average age of the patients was 42.3 ± 10.1 years. Out of 51 patients, there were 60.8% (P=31) females and 39.2%(P=20) males. Out of 51 cholelithiasis patients there were 31.4%(P=16) had Normal Liver and 68.6%(P=35) were positive with Fatty liver disease. Patients with stone size ranges from 1.90mm to 4.6mm hade Grade 1 Fatty liver as shown in table-5.4, Grade 2 Fatty liver was seen in patients with stone size ranges from 4.5mm to 5.8mm. Fatty liver Grade 3 was not observed in any included patient with cholelithiasis. Results of our study showed that both cholelithiasis and Fatty Liver disease are correlated with each other. Females are at higher risk to be affected by these with diseases. Early detection of Fatty liver in patients of cholelithiasis can help patients to prevent them further complications regarded to fatty liver and cholelithiasis and can play important role in health care of society. Keywords: Non-Alcoholic Fatty Liver Disease, Cholelithiasis, Fatty liver, Ultrasonography. DOI: 10.7176/JHMN/91-07 Publication date:July 31st 202