More is Less? Design Free Sample Strategy via Field Experiment and Double/Debiased Machine Learning

Free sample strategy has attracted considerable interest among practitioners and academics, it has been widely adopted in digital content industries (e.g., e-books, music, and videos). There are two issues that have been the continuous concerning and constantly optimized focus. How many free samples should be taken? How to design a personalized free samples strategy considering the contexts? To better understand these issues, we collaborated with an online reading platform in China to design and conduct a field experiment based on Construal Level Theory. The results showed an inverted U-shaped relationship between free sample quantity and consumer purchase decisions and also suggested when free chapters were offered, book popularity and quality were also found to positively moderate consumers’ purchase decisions. Moreover, by combining the causal forest (CF) technique and the double/debiased machine learning model (DML), we develop a personalized free sample strategy and provide managerial implications

Reduction of Uncertainties for Damage Identification of Bridge Based on Fuzzy Nearness and Modal Data

To avoid the false results of deterministic identification methods induced by uncertainties, a fuzzy nearness-based method is proposed for the damage identification of bridge. An improved index based on ratios of modal shape components is used as identification measurements. The knowledge base for damage identification is established through corresponding relationship between fuzzified measurements and damage severities. The damage condition of test samples can be assessed based on approaching principle through fuzzy nearness with rules in knowledge base. A numerical analysis on a multigirder bridge considering uncertainty is presented to demonstrate the effectiveness of the proposed method. The results indicate that the fuzzy nearness-based method can achieve an accurate identification with success rate up to 93.75%. Antinoise analysis and the ability for dealing with incomplete information reveal its robustness

Stabilization diagrams to distinguish physical modes and spurious modes for structural parameter identification

A novel clustering stabilization diagram combined with self adaptive differential evolution algorithm is proposed to identify the modal parameters of civil engineering structures. Compared with the traditional stabilization diagram, the clustering diagram has drawn more attention because it can distinguish physical and spurious modes due to its automatic performance. In this paper, a self adaptive differential evolution algorithm is proposed to optimize the initial clustering centers so as to improve the clustering stabilization diagram. Moreover, this paper presents a new idea that the modal assurance criterion (MAC) composed of mode shapes is selected as the Y-axis to replace the model orders or damping ratios in existing stabilization diagrams. The results of a benchmark test of bridge Z24 and the numerical simulation of a continuous beam and a cable-stayed bridge demonstrate the advantages of the proposed approaches and the reliability of detecting the modal parameters

Lateral distribution calculation of multi-I beam composite curved bridge with slip effect

This paper presents a modified rigid cross beam method to study the lateral distribution of multi-I beam composite curved bridge with slip effect. First, the effective stiffness expression of single composite curved beam with slip effect were established and calculated by the FEM. Secondly, the lateral load distribution of multi-I beam composite curved bridge is obtained by substituting the effective stiffness of the main composite curved beam into the rigid cross beam method. Finally, The FEM numerical examples show that this method can accurately describe the load distribution characteristics of multi-I beam composite curved bridge with slip effect

DHX33 transcriptionally controls genes involved in the cell cycle

The RNA helicase DHX33 has been shown to be a critical regulator of cell proliferation and growth. However, the underlying mechanisms behind DHX33 function remain incompletely understood. We present original evidence in multiple cell lines that DHX33 transcriptionally controls the expression of genes involved in the cell cycle, notably cyclin, E2F1, cell division cycle (CDC), and minichromosome maintenance (MCM) genes. DHX33 physically associates with the promoters of these genes and controls the loading of active RNA polymerase II onto these promoters. DHX33 deficiency abrogates cell cycle progression and DNA replication and leads to cell apoptosis. In zebrafish, CRISPR-mediated knockout of DHX33 results in downregulation of cyclin A2, cyclin B2, cyclin D1, cyclin E2, cdc6, cdc20, E2F1, and MCM complexes in DHX33 knockout embryos. Additionally, we found the overexpression of DHX33 in a subset of non-small-cell lung cancers and in Ras-mutated human lung cancer cell lines. Forced reduction of DHX33 in these cancer cells abolished tumor formation in vivo. Our study demonstrates for the first time that DHX33 acts as a direct transcriptional regulator to promote cell cycle progression and plays an important role in driving cell proliferation during both embryo development and tumorigenesis

Damage identification for irregular-shaped bridge based on fuzzy C-means clustering improved by particle swarm optimization algorithm

Irregular-shaped bridge is an important component of urban overpass and is prone to damage due to severe overloading and material deterioration. Structural damage detection is necessary to prevent bridge failure and guarantee the safe operation of urban traffic. For vibration-based damage detection methods, mode shape of full-scale structure is difficult to be measured with the limited number of sensors, while modal frequency can be obtained accurately and conveniently. This paper aims to propose a two-stage scheme for damage identification using the ratios of modal frequency changes and uniform load surface curvature difference (ULSCD) in damage region. FCM algorithm improved by PSO algorithm (FCM-PSO) is employed to locate damage and predict the damage extent. Firstly, the ratios of modal frequency changes from training cases are classified into several clusters based on FCM-PSO analysis. And the cluster centers for damage locations are constructed. Damage location can be identified by calculating the fuzzy memberships between identification indicator vector and cluster centers of damage locations. After obtaining the damage location, ULSCD values in damage region are established to assess damage severity based on the memberships in damage grades. Damage identification results for typical irregular-shaped bridge demonstrate that the two-stage damage identification method is efficient and accurate to identify the occurrence, location and extent of structural damag

Preparation Parameter Analysis and Optimization of Sustainable Asphalt Binder Modified by Waste Rubber and Diatomite

In this study, crumb rubber and diatomite were used to modify asphalt binder. Wet process was adopted as a preparation method, and the corresponding preparation process was determined firstly. The effects of six preparation parameters (crumb rubber concentration, diatomite concentration, shear time, shear speed, shear temperature, and storing time) on properties of modified asphalt binder (penetration at 25°C, softening point, ductility, viscosity at 135°C, elastic recovery, and penetration index) were investigated, and multiresponse optimization was conducted using the response surface method. The results revealed that softening points, viscosity, elastic recovery, and penetration index increase, while penetration and ductility decrease with the increase of crumb rubber concentration. Softening points, viscosity, and penetration index increase, while penetration and ductility decrease with the increase of diatomite concentration, which presents little influence on elastic recovery of binder. Shear temperature presented significant effects on penetration, softening point, viscosity, and ductility. Shear speed, shear time, and storing time have similar effects on binder properties because of their similar mechanism of action. Based on the model obtained from the response surface method, optimized preparation parameters corresponding to specific criteria can be determined, which possess favorable accuracy compared with experimental results