Osteosarcoma of the ethmoid sinus: About a case

Osteosarcomas of the craniofacial bones account for less than 10% of all osteosarcomas. Primary osteosarcomas of the nasal cavity and paranasal sinus are rare localization (0.5%-8.1% of osteosarcomas occur in this site). Accordingly, we report a case of osteosarcoma arising de novo from the ethmoid bone in a 46-year-old female. Initially, she presented with headache, bilateral epistaxis, and postnasal drip. Biopsy revealed an osteosarcoma ethmoidal. The patient was treated by a neoadjuvant chemotherapy followed by surgical resection and radiotherapy

Solitary plasmacytoma of the skull base: A case report and literature review

Plasmacytoma of the skull base is a rare entity. We present a case of sphenoid plasmacytoma in a 51‐year‐old woman who had nasal obstruction, intermittent epistaxis, headaches, decreasing visual acuity, and diplopia. Computed Tomography (CT) scan and magnetic resonance imaging (MRI) showed a large heterogeneous, expansile lesion measuring 75 mm × 54 mm, centered on the sphenoidal bone and the clivus. Biopsy confirmed the diagnosis of solitary plasmacytoma after ruling out systemic spread by the initial assessment. The patient was successfully managed by external beam radiotherapy and a complete response was obtained after 12 months of follow-up