Angle observation of laser peripheral iridoplasty for the treatment of acute angle-closure glaucoma which could not be controlled by drugs

AIM: To evaluate the effect of laser peripheral iridoplasty(LPIP)to treat acute angle-closure glaucoma(AACG)which could not controlled by drugs and with persistent ocular hypertension. <p>METHODS: Totally 67 patients(69 eyes)with AACG were performed LPIP when intraocular pressure(IOP)was still over 30mmHg after the medicine therapy for 3-6 hours. Visual acuity and intraocular pressure were under detection before laser treatment and 30 minutes, 60 minutes and 2 hours after laser treatment. We measured the anterior chamber depth, width of angle, iris thickness with ultrasound biomicroscope(UBM). Dynamic gonioscopy was used to evaluate the degree of peripheral anterior synechia(PAS).<p>RESULTS: Angle open distance(AOD)after iridoplasty was increased(<i>P</i><0.01). Trabecular-iris angle(TIA)was widen(<i>P</i><0.01)and the extents of PAS were reduced in some cases. IOP reduced at different levels in different time after laser treatment. The mean IOP before acute attack was(53.81±10.22)mmHg. The mean IOP were(33.81±9.22)mmHg,(21.93±7.19)mmHg and(15.16±3.07)mmHg at 30 minutes, 60 minutes and 2 hours after laser treatment respectively(<i>F</i>=151.79, <i>P</i><0.01). Visual acuity increased in all patients. <p>CONCLUSION: LPIP can deepen peripheral anterior chamber, increase the angle access and lower the IOP immediately. It is an important ongoing adjuvant treatment, which can reduce the patients suffering by lowering the IOP quickly, reduce the damage of visual function caused by long-term high intraocular pressure, avoid side effect of the drugs, and can improve the prognosis

Hierarchical Relational Learning for Few-Shot Knowledge Graph Completion

Knowledge graphs (KGs) are known for their large scale and knowledge inference ability, but are also notorious for the incompleteness associated with them. Due to the long-tail distribution of the relations in KGs, few-shot KG completion has been proposed as a solution to alleviate incompleteness and expand the coverage of KGs. It aims to make predictions for triplets involving novel relations when only a few training triplets are provided as reference. Previous methods have mostly focused on designing local neighbor aggregators to learn entity-level information and/or imposing sequential dependency assumption at the triplet level to learn meta relation information. However, valuable pairwise triplet-level interactions and context-level relational information have been largely overlooked for learning meta representations of few-shot relations. In this paper, we propose a hierarchical relational learning method (HiRe) for few-shot KG completion. By jointly capturing three levels of relational information (entity-level, triplet-level and context-level), HiRe can effectively learn and refine the meta representation of few-shot relations, and consequently generalize very well to new unseen relations. Extensive experiments on two benchmark datasets validate the superiority of HiRe against other state-of-the-art methods.Comment: 10 pages, 5 figure

Negative entanglement measure for bipartite separable mixed states

We define a negative entanglement measure for separable states which shows that how much entanglement one should compensate the unentangled state at least for changing it into an entangled state. For two-qubit systems and some special classes of states in higher-dimensional systems, the explicit formula and the lower bounds for the negative entanglement measure have been presented, and it always vanishes for bipartite separable pure states. The negative entanglement measure can be used as a useful quantity to describe the entanglement dynamics and the quantum phase transition. In the transverse Ising model, the first derivatives of negative entanglement measure diverge on approaching the critical value of the quantum phase transition, although these two-site reduced density matrices have no entanglement at all. In the 1D Bose-Hubbard model, the NEM as a function of $t/U$ changes from zero to negative on approaching the critical point of quantum phase transition.Comment: 6 pages, 3 figure