126 research outputs found

    Duration of Classicality of Homogeneous Condensates with Attractive Interactions

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    Dark matter axions and other highly degenerate bosonic fluids are commonly described by classical field equations. In a recent paper \cite{BECprop} we calculated the duration of classicality of homogeneous condensates with attractive contact interactions and of self-gravitating homogeneous condensates in critical expansion. According to their classical equations of motion, such condensates persist forever. In their quantum evolution parametric resonance causes quanta to jump in pairs out of the condensate into all modes with wavevector less than some critical value. We estimated in each case the time scale over which the condensate is depleted and after which a classical description is invalid.Comment: 5 pages, no figures, contributed to the 13th Patras Workshop on Axions, WIMPs and WISPs, Thessaloniki, May 15 to 19, 201

    Research on “Promoting teaching by competition” in the construction of electronic majors in local colleges and universities

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    This paper aims at training practical electronic undergraduate talents in local ordinary undergraduate colleges and universities. Through analyzing the current situation and common construction methods of electronic major construction, this paper proposes to integrate electronic design competition into teaching design. In the practice process, the competition training and daily teaching depth integration, to achieve the purpose of promoting teaching by competition, and at the same time in practice summed up several integration models, the common planning method of promoting teaching by competition is put forward

    Duration of classicality of an inhomogeneous quantum field with repulsive contact self-interactions

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    Quantum fields with large degeneracy are often approximated as classical fields. Here, we show how the quantum and classical evolution of a highly degenerate quantum field with repulsive contact self-interactions differ fromeach other. Initially, the field is taken to be homogeneous except for a small plane-wave perturbation in only one mode. In quantum field theory, modes satisfying both momentum and energy conservation of the quasiparticles, grow exponentially with time. However, in the classical field approximation, the system is stable. We calculate the time scale after which the classical field description becomes invalid

    A Decoding Scheme for Incomplete Motor Imagery EEG With Deep Belief Network

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    High accuracy decoding of electroencephalogram (EEG) signal is still a major challenge that can hardly be solved in the design of an effective motor imagery-based brain-computer interface (BCI), especially when the signal contains various extreme artifacts and outliers arose from data loss. The conventional process to avoid such cases is to directly reject the entire severely contaminated EEG segments, which leads to a drawback that the BCI has no decoding results during that certain period. In this study, a novel decoding scheme based on the combination of Lomb-Scargle periodogram (LSP) and deep belief network (DBN) was proposed to recognize the incomplete motor imagery EEG. Particularly, instead of discarding the entire segment, two forms of data removal were adopted to eliminate the EEG portions with extreme artifacts and data loss. The LSP was utilized to steadily extract the power spectral density (PSD) features from the incomplete EEG constructed by the remaining portions. A DBN structure based on the restricted Boltzmann machine (RBM) was exploited and optimized to perform the classification task. Various comparative experiments were conducted and evaluated on simulated signal and real incomplete motor imagery EEG, including the comparison of three PSD extraction methods (fast Fourier transform, Welch and LSP) and two classifiers (DBN and support vector machine, SVM). The results demonstrate that the LSP can estimate relative robust PSD features and the proposed scheme can significantly improve the decoding performance for the incomplete motor imagery EEG. This scheme can provide an alternative decoding solution for the motor imagery EEG contaminated by extreme artifacts and data loss. It can be beneficial to promote the stability, smoothness and maintain consecutive outputs without interruption for a BCI system that is suitable for the online and long-term application

    Research Progress on the Relationship between Polymorphism and SLE of Vitamin D Metabolic Pathway Related Gene

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    Vitamin D is a class of hormones necessary to maintain normalphysiological activities of the body. A large number of studies have shownthat vitamin D, as a fat-soluble vitamin, is not only related to calcium andphosphorus metabolism, but also closely related to immune regulation,humoral regulation, cell cycle and so on. Systemic Lupus erythema-Tosus(SLE) is a specific autoimmune diffuse connective tissue disease thatcauses tissue and organ damage under the joint action of multiple factorssuch as environment and heredity. Among many factors, the vitamin Dmetabolism pathway gene is particularly important for its influence. Someliterature has shown that the genetic polymorphism of vitamin D metabolicpathway genes is correlated with SLE. Therefore, by referring to relevantliterature, this paper summarized the progress in the research on themechanism of genetic polymorphism of vitamin metabolism pathway genesand the development of SLE

    Ferroptosis: a novel mechanism of cell death in ophthalmic conditions

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    Ferroptosis, a new type of programmed cell death proposed in recent years, is characterized mainly by reactive oxygen species and iron-mediated lipid peroxidation and differs from programmed cell death, such as apoptosis, necrosis, and autophagy. Ferroptosis is associated with a variety of physiological and pathophysiological processes. Recent studies have shown that ferroptosis can aggravate or reduce the occurrence and development of diseases by targeting metabolic pathways and signaling pathways in tumors, ischemic organ damage, and other degenerative diseases related to lipid peroxidation. Increasing evidence suggests that ferroptosis is closely linked to the onset and progression of various ophthalmic conditions, including corneal injury, glaucoma, age-related macular degeneration, diabetic retinopathy, retinal detachment, and retinoblastoma. Our review of the current research on ferroptosis in ophthalmic diseases reveals significant advancements in our understanding of the pathogenesis, aetiology, and treatment of these conditions

    Common and distinct equity preferences in children and adults

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    Fairness plays a crucial role in children’s social life and has garnered considerable attention. However, previous research and theories primarily examined the development of children’s fairness behaviors in the conflict between self-interest motivation and fairness-complying motivation, neglecting the influence of advantage-seeking motivation. Moreover, despite the well-established role of gain/loss frame in human decision-making, it remains largely unclear whether the framing effect modulates fairness behaviors in children. It was hypothesized that children would exhibit advantage-seeking motivation resulting in more selfish behaviors in the loss context. To examine the hypothesis, we combined an adapted dictator game and computational modeling to investigate various motivations underlying fairness behaviors of children in both loss and gain contexts and to explore the developmental directions by contrasting children and adults. In addition, the current design enabled the dissociation between fairness knowledge and behaviors by asking participants to decide for themselves (the first-party role) or for others (the third-party role). This study recruited a total of 34 children (9–10 years, Mage = 9.82, SDage = 0.38, 16 females) and 31 college students (Mage = 19.81, SDage = 1.40, 17 females). The behavioral results indicated that children behaved more selfishly in first-party and more fairly in third-party than adults, without any significant framing effects. The computational results revealed that both children and adults exhibited aversion to advantageous and disadvantageous inequity in third-party. However, they showed distinct preferences for advantageous inequity in first-party, with advantage-seeking preferences among children and aversion to advantageous inequity among adults. These findings contribute to a deeper understanding of children’s social preferences and their developmental directions

    CDC20 facilitates the proliferation of esophageal carcinoma cell by stabilizing NLRP3 expression

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    Background and purpose: Esophageal carcinoma (ESCA) is one of the malignant tumors with high mortality rate, and the underlying mechanism of its development is largely unknown. CDC20 plays an important role in tumorigenesis, and its dysregulated expression is closely related to tumor occurrence and development. The expression of CDC20 is increased in a variety of tumors, and knocking down CDC20 can inhibit tumor cell proliferation. NLRP3 is the main component of the inflammasome, and inflammasome is also closely related to tumor occurrence and development. Here, our study aimed to investigate whether CDC20 promotes the proliferation of ESCA cells through NLRP3 and its regulatory mechanism. Methods: The expression levels of CDC20 and NLRP3 genes in ESCA patients were analyzed using The Cancer Genome Atlas (TCGA) detabase and GTEx public database. We collected clinical and pathological data and tissues from 80 ESCA patients at the First Affiliated Hospital of Xinxiang Medical College, and detected the protein expression of NLRP3 in ESCA patients through immunohistochemistry staining. This study was approved by the Ethics Committee of the First Affiliated Hospital of Xinxiang Medical College (Number: EC-021-137). We studied the effects of knocking down CDC20 and NLRP3 gene on the proliferation ability of esophageal squamous cell carcinoma cells EC9706 and KYSE150 using short hairpin RNA (shRNA) technology. Co-immunoprecipitation (Co-IP), proteasome inhibitors and ubiquitination experiments were used to detect whether CDC20 interacts with NLRP3, and to elucidate whether CDC20 regulates NLRP3 expression through the ubiquitination pathway. This study was approved by the Ethics Committee of the First Affiliated Hospital of Xinxiang Medical College (Number: EC-021-137). Results: The TCGA database analysis showed that the expression levels of CDC20 and NLRP3 mRNA were significantly higher in the cancer tissues of ESCA patients than in the adjacent tissues. The immunohistochemistry results further showed that compared with adjacent tissues, the protein expression levels of CDC20 and NLRP3 were increased in ESCA tissues. Knocking down CDC20 and NLRP3 genes inhibited the proliferation of ESCA cells. Co-IP, proteasome inhibitors and ubiquitination experiments confirmed that CDC20 interacted with NLRP3 through its leucine-rich repeat (LRR), and CDC20 stabilized its expression by promoting NLRP3 ubiquitination. Conclusion: CDC20 and NLRP3 are upregulated in ESCA tissues, and CDC20 stabilizes their expression through ubiquitination of NLRP3, promoting ESCA cell proliferation. This suggests that CDC20 and NLRP3 may be potential diagnostic targets for ESCA
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