26 research outputs found

    Comparative Study of Turbo Equalisers Using Convolutional Codes and Block-Based Turbo Codes for GMSK Modulation

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    In contrast to previously proposed turbo equalisers, where typically non-iterative channel decoders were used, this paper compares the performance of partial-response GMSK turbo equalisers using two different encoders, namely block BCH turbo codes and convolutional codes. The BER performance is assessed over non-dispersive Gaussian channels, and dispersive Rayleigh fading channels

    Joint Channel Equalisation and Channel Decoding

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    A non-iterative joint equaliser and decoder scheme is proposed which outperforms the iterative turbo equaliser by ~3.4dB at a BER of 10E-3 over a five-path Gaussian channel

    Cholera Toxin B: One Subunit with Many Pharmaceutical Applications

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    Cholera, a waterborne acute diarrheal disease caused by Vibrio cholerae, remains prevalent in underdeveloped countries and is a serious health threat to those living in unsanitary conditions. The major virulence factor is cholera toxin (CT), which consists of two subunits: the A subunit (CTA) and the B subunit (CTB). CTB is a 55 kD homopentameric, non-toxic protein binding to the GM1 ganglioside on mammalian cells with high affinity. Currently, recombinantly produced CTB is used as a component of an internationally licensed oral cholera vaccine, as the protein induces potent humoral immunity that can neutralize CT in the gut. Additionally, recent studies have revealed that CTB administration leads to the induction of anti-inflammatory mechanisms in vivo. This review will cover the potential of CTB as an immunomodulatory and anti-inflammatory agent. We will also summarize various recombinant expression systems available for recombinant CTB bioproduction
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