146 research outputs found
Mathematical Modeling and Simulation of Ventricular Activation Sequences: Implications for Cardiac Resynchronization Therapy
Next to clinical and experimental research, mathematical modeling plays a crucial role in medicine. Biomedical research takes place on many different levels, from molecules to the whole organism. Due to the complexity of biological systems, the interactions between components are often difficult or impossible to understand without the help of mathematical models. Mathematical models of cardiac electrophysiology have made a tremendous progress since the first numerical ECG simulations in the 1960s. This paper briefly reviews the development of this field and discusses some example cases where models have helped us forward, emphasizing applications that are relevant for the study of heart failure and cardiac resynchronization therapy
Asynchronous vegetation phenology enhances winter body condition of a large mobile herbivore
Role of Appetite-Regulating Peptides in the Pathophysiology of Addiction: Implications for Pharmacotherapy
Augmentation of respiratory sinus arrhythmia in response to progressive hypercapnia in conscious dogs
Cardiac arrhythmias in the conscious dog after excision of the sinoatrial node and crista terminalis.
Multiple-lead QRS changes with exercise testing. Diagnostic value and hemodynamic implications.
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