Takayasu Arteritis Initially Mimicking Infective Endocarditis

Takayasu’s arteritis (TA) is a chronic inflammatory disease that affects large vessels, predominantly the aorta and its main branches, leading to vessel wall thickening, fibrosis and stenosis. Cardiac and vascular symptoms are also commonly present at disease onset. In TA with thoracic or abdominal involvement, although murmur can be present at physical examination, the pulse difference may be absent. Here, we report a case of TA who initially resembled infective endocarditis and had widespread thoracic murmur

A case of colistin-induced fixed drug eruption

Several medicines, especially antimicrobials, play a rolein the etiology of fixed drug eruption (FDE). The clinicalmanifestation is quite typical for a drug-induced reaction.FDE which developed in an 83-year-old male patientwho has been administered colistin due to Acinetobacterpneumonia is presented here since it is very rarely seen.Therefore colistin should also be considered in the differentialdiagnosis of FDE. J Clin Exp Invest 2013; 4 (3):374-376Key words: Fixed drug eruption, etiology, colisti

A rare cause of liver abscess secondary to hydatid cyst: pseudomonas stutzeri

Pseudomonas stutzeri is non-fermentative gram negative bacteria which rarely leads to infections. In this report, we presented for the first time a liver abscess which was caused by P. stutzeri. [Cukurova Med J 2016; 41(0.100): 17-19

Primary Bacteremia Associated With Sphingomonas paucimobilis During the Late Period in a Patient With Ventriculoperitoneal Shunt After Neurosurgery With Literature Review

Hakyemez, Ismail/0000-0001-6133-9604WOS: 000300408500009Sphingomonas paucimobilis is a Gram-negative aerobic rod, which is nonfermentative, nonspore forming, catalase positive, and oxidase positive. It is believed that the natural habitat of this organism is the natural environment, and it is also found in hospital settings. The infections caused by the bacteria are rarely life threatening. A 46-year-old woman was admitted to our clinic with right flank pain, groin pain, and fever. On clinical examination, right costovertebral angle pain and an operation scar in the temporal region were observed. A review of her medical history revealed an operation for subarachnoid hemorrhage secondary to aneurysm and a ventriculoperitoneal shunt 6 weeks before admission. Ceftriaxone 2 x 1 g/day was started. No growth was detected in urine, cerebrospinal fluid, and temporal fluid cultures; however, a Gram-negative rod grew in one of the blood cultures on the second day of treatment. Intravenous ciprofloxacin 400 mg 2 x 1/day was added to treatment. Ceftriaxone treatment was switched to cefoperazon-sulbactam 1 gr 2 x 1/day. No growth was observed in urine and blood control cultures on the third day of treatment. Cefoperazon-sulbactam was stopped on the 10th day, and ciprofloxacin was continued until the 21st day. In English literature, the presence of Sphingomonas paucimobilis bacteremia after neurosurgery has not been previously reported

Infective endocarditis case due to streptococcus parasanguinis presented with spondylodiscitis

Streptococcus parasanguinis is a natural member of oral flora. It is an opportunistic pathogen, and rarely cause systemic infections due to it's low virulence. Subacute infective endocarditis may present with various clinical manifestations (eg., spondylodiscitis). A sixty-five years old male patient from Northern Iraq has referred to our emergency service with high fever, weight loss, back pain and inability to walk. The patient was a veterinarian. He was operated three years ago for colonic carcinoma and irradiated. In magnetic resonance imaging, spondylodiscitis was detected localized in lumbar 1-2 region. Transthorasic echocardiography demonstrated aortic valve vegetation. S. parasanguinis was identified in the blood cultures. In conclusion; all in all, it's remarkable to isolate S. parasanguinis as a causal agent of infective endocarditis in a patient who is a veterinarian with history of colonic carcinoma presented with clinical manifestation of spondylodiscitis. [Cukurova Med J 2016; 41(3.000): 591-594

Microbial colonization of the external auditory canal and nose in hemodialysis patients

Alcelik, Aytekin/0000-0002-3156-1076; Hakyemez, Ismail/0000-0001-6133-9604; DURAN, ARIF/0000-0002-2119-9448WOS: 000307479600026PubMed: 22926372Aim The aim of our study is to determine the microbiology of the external auditory canal and nose in uremic patients on chronic dialysis. Methods All patients undergoing regular hemodialysis for at least 3 months were included in this study. The nasal and external auditory canal swabs were collected from 83 haemodialysed patients. Results From 83 patients (37 females, 46 males) nasal and external auditory canal cultures were obtained. Mean duration on dialysis was 41.75 +/- 45 months and mean age of patients was 61 13 years. Microflora in the nasal cavities (70/80, 87.5%) and external auditory canal (48/59, 81.3%) were similar in all culture positive patients (coagulase-negative staphylococci). Coexistence of coagulase-negative staphylococci and diphteroids was detected in 20 patients' (25.0%) nasal vestibule and in eight patients' (13.5%) external auditory canal. Conclusion Microflora in the nasal cavities and external auditory canal were similar in chronic renal patients. External auditory canal microflora was not associated with history of diabetes mellitus, hepatitis status and starting date of hemodialysis in our study

Fascioliasis : a not rare cause of hypereosinophilia in developing countries, present in developed too

<p>Fascioliasis, which is a worlwide parasitic zoonosis,endemic in south-est mediterranean areas, but uncommon in other areas. Clinical signs are usually non-specific. A 32 year old male patient was admitted to our hospital with complaints of abdominal pain, diarrhea, fatigue, nausea, lost of apetite, itching, cough, night sweats and weight loss. Complete blood count revealed hypereosinophilia. The abdominal ultrasound scan was normal. But computed tomography scan revealed irregular nodular lesions in periportal area of the liver. Based on these clinical and radiological signs and continuous hypereosinophilia, the patient was serologically investigated for <em>Fasciola hepatica</em> infection. <em>F. hepatica</em> indirect hemagglutination test in serum was positive at a titer of 1/1280. Single dose Triclabendasole 10mg/kg was administered and repeated two weeks later. Clinical and laboratory signs were completely resolved after treatment.  Serological tests for fascioliasis should be included in all patients with  hypereosinophilia and abnormal liver CT.</p&gt

The effect of Enterobius vermicularis infection (oxyuriasis) on eosinophil and IgE levels in allergic rhinitis

Objectives: Elevated levels of serum IgE and eosinophilia are the indicators of atopy and intestinal parasiticinfections. We evaluated the effect of Enterobius vermicularis infection (enterobiasis) on blood eosinophilcount and IgE levels in allergic rhinitis.Methods: A total of 110 patients diagnosed with allergic rhinitis (with symptoms of rhinorrhea, itchy nose andnasal congestion) consisting of 41 (37.27%) males and 69 (62.73%) females were examined. Forty-one(37.27%) patients with enterobiasis were selected as the study group. The remaining 69 (62.73%) patientsaccepted as the control group.Results: In the study group the mean serum total IgE level and mean serum eosinophil count were 393.10 159.83 IU/mL and 0.56 0.04 103/mL, respectively. In the control group the mean serum total IgE level andmean serum eosinophil count were 236.91 63.55 IU/mL and 0.37 0.12 103/mL, respectively. The differencebetween the two groups was statistically significant for serum total IgE levels (p 0.05) but not for serumeosinophil count (p 0.05). The correlation coefficients between serum total IgE level and eosinophil countwere statistically insignificant (p 0.05).Conclusions: More comprehensive and long-term placebo-controlled studies should be performed in order tofind the answer to the question of whether helminth infections play a role in allergic disease