Long-term results of cyclosporine-steroid therapy in 131 non-matched cadaveric renal transplants.

One-hundred-and-twenty-eight recipients of 131 consecutive, non-matched cadaver renal allografts were treated with cyclosporine and steroids. They have been followed for 4 to 6 yr. Cumulative patient survival at 1-yr was 92.2% and at 6yr it is 77.8%. Cumulative graft survival at 1-yr was 79.4% and at 6 yr it is 50.0%. After the high-risk 1st yr, the rate of graft loss was even and similar to that reported after the 1st yr for grafts treated with azathioprine and steroids. This indicates that cyclosporine nephrotoxicity has not had an obvious adverse effect on the survival of chronically functioning grafts. The results were better with primary grafting versus retransplantation, but were not significantly influenced by age, diabetes mellitus, or a delayed switch in patients from cyclosporine to azathioprine. We have concluded that cyclosporine-steroid therapy is safe and effective for long-term use after cadaveric renal transplantation

2XMMi J225036.9+573154 - a new eclipsing AM Her binary discovered using XMM-Newton

We report the discovery of an eclipsing polar, 2XMMi J225036.9+573154, using XMM-Newton. It was discovered by searching the light curves in the 2XMMi catalogue for objects showing X-ray variability. Its X-ray light curve shows a total eclipse of the white dwarf by the secondary star every 174 mins. An extended pre-eclipse absorption dip is observed in soft X-rays at phi=0.8-0.9, with evidence for a further dip in the soft X-ray light curve at phi~0.4. Further, X-rays are seen from all orbital phases (apart from the eclipse) which makes it unusual amongst eclipsing polars. We have identified the optical counterpart, which is faint (r=21), and shows a deep eclipse (>3.5 mag in white light). Its X-ray spectrum does not show a distinct soft X-ray component which is seen in many, but not all, polars. Its optical spectrum shows Halpha in emission for a fraction of the orbital period.Comment: Accepted for publication in MNRA

The isotropic Compton profile difference across the phase transition of VO2_2

We studied the isotropic Compton profile of the prototypical oxide VO$_2$ across the temperature induced electronic and structural phase transition at T$_C$ $\approx$ 340 K. We show that the phase transition leaves an observable signal, which facilitates Compton scattering studies of electronic structure and phase transitions in complex solids in powder form. We compare the experimental results with density functional theory calculations and find agreement in the shape of the difference profile, although the amplitude of the observed features is overestimated. The origin of the disagreement is discussed and we argue that it mainly originates mostly correlation effects beyond our current calculations and possibly to some extent, from thermal motion