In vivo study of antimutagenic and antioxidant activity of Glycyrrihza glabra root extract

The studying was aimed to inhibition the mutagenecity and oxidation of genomic DNA by use methanol-water extract of Glycyrrihza glabra root (GL) against anticancer drug cyclophosphomide in rats by use DNA fragmentation test, the extract characterized by thin layer chromatography TLC, and antioxidant activity by use β- carotene spray, the experiment design to use tow single dose of GL and single dose of the drug in three interaction, extract before, with and after the drug to investigate the mechanism of which extract effect inside cell. Four multiple doses for drug and extract to investigate the accumulation effect in DNA the results show that extract is contain of different polar compound and have antioxidant activity, so the extract is bio-antimutagenesis and poor dismutagenesis activity, the extract can inhibit accumulation effect of mutagenecity and oxidation activity of the drug

Effect of Pollutant Water on Some Organs and Blood Parameters in Rats

Water pollution causes dangerous problems in our life. The present study aims to determination effect of chemical polluted water on blood parameter and histological changes in rat organs using Wight albino rats. For this study Hilla fabric plant waste water is used as drinking water to the rats for 30 days. Results show that polluted water causes increased in W.B.Cs count and histopathological changes in liver and kidne