Peutz-Jeghers Syndrome presenting as Intussusception in a young female: A Case Report

Peutz-jeghers syndrome is rare condition with autosomal dominant inheritance. It is due to the mutation in a tumor suppressor gene SK 11 at chromosome no 9. It has a very characteristic presentation. Patient usually presents at a young age with intestinal obstruction due to polyps leading to intussusception. Also there is melanosis at perioral, digits and perineal regions. There is very strong association of cervical and breast carcinoma in females and testicular tumors in males. GIT, pancreatic and lung malignancies occur in both sexes. Regular follow up and screening are necessary for early detection of malignancies. We present a case of young girl who presented with intestinal obstruction along with other signs and symptoms of peutz-jeghers syndrome. Exploratory laparotomy revealed jejunoileal intussusception and hamartomatous polyps. Patient and other family members were advised screening studies of associated malignancies and regular follow up

Islamic vs. Conventional Equity Markets: A Multifractal Cross-Correlation Analysis with Economic Policy Uncertainty

There is ample evidence that Islamic stock markets perform differently from conventional stock markets, particularly when economic policy uncertainty (EPU) or any other uncertainty such as geopolitical uncertainty is present. Considering this context, this paper examines the US EPU’s cross-correlation with both conventional and Islamic stock markets from the perspective of multifractality. Daily stock market prices of five main countries are considered: US, Thailand, Indonesia, Pakistan, and India. Using the multifractal detrended cross-correlation analysis (MF-DCCA), we validate the existence of long-range cross-correlation between US EPU and all the stock markets considered, demonstrating that all pairs of US EPU have strong power law and multifractal characteristics. Furthermore, all pairs display varying levels of multifractal strength, with the US EPU and US conventional stock market exhibiting the strongest multifractal patterns. Additionally, a cross-correlation between US EPU and the different stock markets is found to be persistent. The results of this study are pertinent to the various market participants in both conventional and Islamic markets, particularly investors, who may be able to draw useful conclusions from them for purposes such as portfolio diversification

Amelioration by Morus Nigra Fruit Extract on Testes, Seminiferous Tubules and Spermatic Cells by Chromium Induced Histopathologies in Mice

Male toxicology in terms of histopathology of testes, histometery of seminiferous tubules and various spermatic cells against short-term hexavalent chromium Cr(VI) exposure & their ameliorations upon post treatment of Morus nigra fruit pulp extract (MnFPE) were studied. There were 3 groups of animals named as 1. Control (C) group: received free normal drinking water for 15 days; 2. Chromium (Cr VI) group: received hexavalent chromium Cr(VI) in drinking water for 10 days; 3. Chromium+Morus nigra (Cr VI+Mn) group: received Cr(VI) in drinking water for 10 days; additionally received 0.2mL MnFPE twice a day for next 5 days. The whole study duration was 15 days and animals of all groups were dissected at day 16th. Histopathological results shows drastic pathological changes in testicular tissue on chromium Cr(VI) exposure group like necrosis of interstitial tissues, ruptured seminiferous tubules, scattered spermatogonia and dislodged spermatogenic cells, increased number of clubs headed sperms and lack of tail in dislodged parrot beak headed spermatozoa in Cr(VI) treated group. Most of these pathological signs were recovered effectively in Cr(VI)+Mn group. Histometeric results give a strong evidence for the above mentioned histological results. Most of these micrometric alterations were found in Cr(VI) group were addressed properly in Cr(VI)+Mn group. These findings suggest that MnFPE has got curative properties against short-term hexavalent chromium Cr(VI) exposure