8 research outputs found
Fabrication, Characterization and Thermo-physical Property Evaluation of SiC Nanofluids for Heat Transfer Applications
Experimental study on convective heat transfer of nanofluids in turbulent flow: Methods of comparison of their performance
Combined effect of physical properties and convective heat transfer coefficient of nanofluids on their cooling efficiency
Exogenous application of humic acid and salicylic acid to alleviate seedling drought stress in two corn ( Zea mays
When signalling goes wrong: pathogenic variants in structural and signalling proteins causing cardiomyopathies
Cardiomyopathies are a diverse group of cardiac disorders with distinct phenotypes, depending on the proteins and pathways affected. A substantial proportion of cardiomyopathies are inherited and those will be the focus of this review article. With the wide application of high-throughput sequencing in the practice of clinical genetics, the roles of novel genes in cardiomyopathies are recognised. Here, we focus on a subgroup of cardiomyopathy genes [TTN, FHL1, CSRP3, FLNC and PLN, coding for Titin, Four and a Half LIM domain 1, Muscle LIM Protein, Filamin C and Phospholamban, respectively], which, despite their diverse biological functions, all have important signalling functions in the heart, suggesting that disturbances in signalling networks can contribute to cardiomyopathies.</p