7 research outputs found

    Data Defense: Examining Fintech’s Security and Privacy Strategies

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    This article aims to investigate the problem of security and privacy in the fintech business, since the use of digital technologies has increased in last few years. In this context, we conducted a survey of fintech companies to understand how they are addressing the security and privacy issue and what are the potential risks and benefits for consumers. According to the results, fintech companies are exploiting a range of technical, regulatory, and compliance measures to ensure the security and privacy of financial data, such as encryption, access controls, and data governance policies. However, we attempted to pinpoint open issues as well as prospective research directions. In such settings, there is a need to better understand the efficiency of different privacy and security measures, as well as the potential risks and advantages for customers while they are using fintech services. This article recommends that future research broaden its scope and delve further into the security and privacy issues of specific types of fintech services

    Wireless Communications beyond Antennas: The Role of Reconfigurable Intelligent Surfaces

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    Reconfigurable intelligent surfaces (RISs) are a new and emerging technology that has the potential to revolutionize the way that wireless communication systems are designed and implemented. These surfaces are made up of a large number of small, individually controllable elements, each of which can be used to manipulate the phase and amplitude of the electromagnetic waves that pass through it. This allows them to perform a wide range of functions, including wireless power transfer, beamforming, and cloaking. In this work, we provide an overview of the principles and applications of reconfigurable intelligent surfaces, and we discuss the advantages and challenges of these surfaces in wireless communications. We also provide an overview of the current state of research in this area. Moreover, we outline the future directions for the development of these surfaces

    A hybrid voltage-current compensator using a synchronous reference frame technique for grid-connected microgrid under nonlinear load conditions

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    Power quality is important for the reliable operation of power grids. Unwanted harmonics cause serious degradation of power quality. This problem is more obvious for distributed generations connected to a microgrid. To solve this issue, this paper proposes an improved voltage and current (VI) compensator to collectively suppress voltage and current harmonics in a three-phase hybrid fuel cell and photovoltaic grid-connected inverters using a synchronous reference frame (SRF) based technique in the presence of non-linear loads. It is shown that the proposed compensator can effectively reduce the harmonic contents in voltage and current without any dependence on offset devices such as active and passive filters. Simulations in MATLAB/Simulink show that the proposed control strategy not only reduces the total harmonic distortion to less than 5% (as per the IEEE 519 standard) but also results in the least total harmonic distortion (THD) as compared to existing techniques

    Computational and theoretical chemistry of newly synthesized and characterized 2,2’-(5,5’-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-acetamides

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    Abstract Energetic heterocycles, including pyridines, triazoles, and tetrazoles, exhibit greater density, heats of formation, and oxygen balance compared to their carbocyclic counterparts, making them a promising approach for synthesizing novel bis-tetrazole acetamides. Synthesized compounds A-F, some of which feature a chlorine atom attached to the phenyl ring, serve as valuable synthons for aryl coupling reactions. Analysis via 1H-NMR and 13C-NMR spectroscopy, as well as density functional considerations through B3LYP functional correlation with 6-311 +  + G(d) and 6-31G(d) basis set, revealed the observed LUMO/HOMO energies and charge transfer within the molecule. Additionally, the dipole moment, chemical hardness, softness, ionization potential, local reactivity potential via Fukui indices and thermodynamic properties (entropy, enthalpy, and Gibbs free energy) of the molecule were calculated through density functional theory studies. In addition, Molecular Docking studies were conducted to investigate the anti-cancer potential of synthesized heterocyclic compounds against caspase 3, NF-KAPPA-B and P53 protein. Molecular docking analysis demonstrated a potent interaction between 2,2’-(5,5’-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-(2,4-dinitrophenyl) acetamides (6d) and TP53 and NF-KAPPA-B with binding energies of − 11.8 kJ/mol and − 10.9 kJ/mol for TP53 and NF-KAPPA-B, respectively. Similarly, 2,2’-(5,5’–(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-(2-chlorophenyl) acetamides (6f) exhibited a strong interaction with caspase-3 with binding energy of -10.0 kJ/mol, indicating their potential as therapeutic agents against these proteins. Furthermore, the findings of current study was further strengthen by 100 ns molecular dynamics (MD) simulations. Finally, theoretical studies of oxygen balance and nitrogen percentage suggest that these molecules can be utilized as energetic materials. Graphical Abstrac

    Computational and theoretical chemistry of newly synthesized and characterized 2,2’-(5,5’-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-acetamides

    No full text
    Energetic heterocycles, including pyridines, triazoles, and tetrazoles, exhibit greater density, heats of formation, and oxygen balance compared to their carbocyclic counterparts, making them a promising approach for synthesizing novel bis-tetrazole acetamides. Synthesized compounds A-F, some of which feature a chlorine atom attached to the phenyl ring, serve as valuable synthons for aryl coupling reactions. Analysis via 1H-NMR and 13C-NMR spectroscopy, as well as density functional considerations through B3LYP functional correlation with 6-311 + + G(d) and 6-31G(d) basis set, revealed the observed LUMO/HOMO energies and charge transfer within the molecule. Additionally, the dipole moment, chemical hardness, softness, ionization potential, local reactivity potential via Fukui indices and thermodynamic properties (entropy, enthalpy, and Gibbs free energy) of the molecule were calculated through density functional theory studies. In addition, Molecular Docking studies were conducted to investigate the anti-cancer potential of synthesized heterocyclic compounds against caspase 3, NF-KAPPA-B and P53 protein. Molecular docking analysis demonstrated a potent interaction between 2,2’-(5,5’-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-(2,4-dinitrophenyl) acetamides (6d) and TP53 and NF-KAPPA-B with binding energies of − 11.8 kJ/mol and − 10.9 kJ/mol for TP53 and NF-KAPPA-B, respectively. Similarly, 2,2’-(5,5’–(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-(2-chlorophenyl) acetamides (6f) exhibited a strong interaction with caspase-3 with binding energy of -10.0 kJ/mol, indicating their potential as therapeutic agents against these proteins. Furthermore, the findings of current study was further strengthen by 100 ns molecular dynamics (MD) simulations. Finally, theoretical studies of oxygen balance and nitrogen percentage suggest that these molecules can be utilized as energetic materials.Fil: Ejaz, Syeda Abida. University of Bahawalpur; PakistánFil: Farid, Aftab. Quaid-I-Azam University Islamabad; PakistánFil: Zargar, Seema. King Saud University; Arabia SauditaFil: Channar, Pervaiz Ali. Dawood University of Engineering and Technology Karachi; PakistánFil: Aziz, Mubashir. The Islamia University of Bahawalpur; PakistánFil: Wani, Tanveer A.. King Saud University; Arabia SauditaFil: Attaullah, Hafiz Muhammad. King Saud University; Arabia SauditaFil: Ujhan, Rabail. University of Sindh; PakistánFil: Tehzeeb, Arfa. Quaid-I-Azam University Islamabad; PakistánFil: Saeed, Aamer. Quaid-I-Azam University Islamabad; PakistánFil: Ali, Hafiz Saqib. University of Manchester; Reino UnidoFil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentin

    Exploration of newly synthesized azo-thiohydantoins as the potential alkaline phosphatase inhibitors via advanced biochemical characterization and molecular modeling approaches

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    Abstract In the current study, Azo-Thiohydantoins derivatives were synthesized and characterized by using various spectroscopic techniques including FTIR, 1H-NMR, 13C-NMR, elemental and HRMS analysis. The compounds were evaluated for alkaline phosphatase activity and it was observed that among all the synthesized compounds, derivative 7e exhibited substantial inhibitory activity (IC50 = 0.308 ± 0.065 µM), surpassing the standard inhibitor (L–Phenyl alanine, IC50 = 80.2 ± 1.1 µM). Along with this, these derivatives were comprehensively examined regarding the electronic properties and reactivity of the synthesized compounds using Density Functional Theory (DFT) calculations, where the results were found very promising and the synthesized compound were found stable. After that, SwissADME evaluations highlighted compounds for their favorable physicochemical properties, including solubility and drug-likeness. Molecular docking exhibited the strong binding affinities of 7f and 7e derivatives with intestinal alkaline phosphatase (IAP), further supported by Molecular Dynamics (MD) simulations. This comprehensive integration of experimental and computational approaches sheds the light on the potential therapeutic applications of the synthesized compounds. By providing a detailed investigation of these aspects, this research opens the avenues for the development of novel pharmacologically active compounds with diverse applications
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