10 research outputs found
Effective Treatment of Chronic Radiation Proctitis Using Radiofrequency Ablation
Endoscopic argon plasma coagulation and bipolar electrocautery are currently
preferred treatments for chronic radiation proctitis, but ulcerations and
strictures frequently occur. Radiofrequency ablation (RFA) has been successful
for mucosal ablation in the esophagus. Here we report the efficacy of RFA with
the BarRx Halo90 system in three patients with bleeding from chronic
radiation proctitis. In all cases, the procedure was well tolerated and
hemostasis was achieved after 1 or 2 RFA sessions. Re-epithelialization of
squamous mucosa was observed over areas of prior hemorrhage. No stricturing or
ulceration was seen on follow-up up to 19 months after RFA treatment. Real-time
endoscopic optical coherence tomography (EOCT) visualized epithelialization and
subsurface tissue microvasculature pre- and post-treatment, demonstrating its
potential for follow-up assessment of endoscopic therapies