Results of the Study for the Antihypertensive Effect in the Panzeria Alaschanica Kupr Plant

Objectives: To study the effect of the plant Panzeria alaschanica Kupr on lowering blood pressure. Methods: The experiment was performed using Sharon Leng Hong Ong (2009) using a male rat weighing 150 - 250 grams. On days 5, 8, 13, and 15 of the experiment, ECG, heart rate, and arterial pressure were measured in the rat’s tail with a Neurobotic systole 1.2 instruments. At the end of the experiment, the content of renin, angiotensin II and aldosterone were determined by enzyme-linked immunosorbent assay. Results: According to the results of the study, the experimental group of plant Panzeria alaschanica Kupr ingested a dose of 160 mg/kg of renin 36.8 % compared with the control group that caused the pathological model, the amount of aldosterone in animals plant Panzeria alaschanica Kupr who ingested a dose of 32 mg/kg were 43.5 % of the ingested animals compared with the pathogenic group, the amount of angiotensin II in the plant Panzeria alaschanica Kupr was 64 mg/kg animals that ingested in, was reduced by a statistically significant difference (p < 0.05) of 34.3 % compared with the control group generated by the pathological model. Conclusion: Panzeria alaschanica Kupr has a 36.8 % reduced blood pressure by affecting the renin, angiotensin, and aldosterone systems

The Effect of Panzeria Alaschanica Kupr. on Carrageenan-Induced Acute Inflammation in Rats

Objectives: In the present study, we aimed to investigate the effect of Panzeria alaschanica Kupr. (P. alaschanica) on carrageenan-induced acute inflammation in rats. Method: Carrageenan-induced rat paw edema was used to evaluate the anti-inflammatory activity. P. alaschanica extract (32, 64, and 160 mg/kg/ BW) or vehicle was given orally 60 minutes before the subplantar injection of carrageenan. Ibuprofen (100 mg/kg) was used as a standard drug. The carrageenan-injected paw was measured 30, 60, 120, 180, and 240 minutes after the carrageenan injection. The levels of serum tumor necrosis factor (TNF)-α, interleukin (IL)-ELISA measured 1β, and IL-6. Results: The P. alaschanica at all given doses significantly (p˂0.01) inhibited carrageenan-induced rat paw edema. Moreover, it significantly reduced TNF-α, IL-1β, and IL-6 serum levels at different doses (p˂0.01). The anti-inflammatory effect of P. alaschanica was comparable to ibuprofen. Conclusion: P. alaschanica has an anti-inflammatory impact on carrageenan-induced paw edema in rats. The mechanism of action may partly be via reducing the levels of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum