19 research outputs found

    Elevated Plasma Von Willebrand Factor and Propeptide Levels in Malawian Children with Malaria

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    In children with malaria plasma VWF and propeptide levels are markedly elevated in both cerebral and mild paediatric malaria, with levels matching disease severity, and these normalize upon recovery. High levels of both markers also occur in retinopathy-negative 'cerebral malaria' cases, many of whom are thought to be suffering from diseases other than malaria, indicating that further studies of these markers will be required to determine their sensitivity and specificity

    Von Willebrand factor in the vessel wall mediates platelet adherence

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