5 research outputs found
Efect of antiseptic gels in the microbiologic colonization of the suture threads after oral surgery
Te work was supported by the Oral Medicine, Oral surgery and Implantology Unit. School of Medicine and
Dentistry, University of Santiago de Compostela, Santiago de Compostela, Spain.Three diferent bioadhesive gels were evaluated in a double-blind randomized clinical trial in which
microbial growth in the suture thread was assessed following post-surgical application of the
aforementioned gels. Also assessed in this trial were, the intensity of post-surgical pain as well as
the degree of healing of the patients’ surgical wounds. A total of 21 patients (with 42 wisdom teeth)
participated in this trial. Chlorhexidine gel, chlorhexidine-chitosan gel, and hyaluronic acid gel were
evaluated, with a neutral water-based gel serving as the control agent. The aerobic and facultative
anaerobic bacterial recovery on blood agar was lower in the placebo group than in the experimental
groups. The most signifcant diference (p=0.04) was observed in the chlorhexidine-chitosan group. in
which the growth of Blood Agar and Mitis Salivarius Agar was signifcantly higher than in the placebo
group. The intensity of post-surgical pain was very similar among all the groups. Signifcantly better
healing rates were observed in the patients treated with chlorhexidine-chitosan gel when compared
with those who used the placebo gel (p=0.03), and in particular when compared with those patients
who used hyaluronic acid gel (p=0.01). Through our microbiological analyses, we were able to conclude
that none of the bioadhesive gels tested resulted in benefcial reductions in the bacterial/fungal
populations. However, the healing rates of patients who were treated with chlorhexidine-chitosan were
better than those of the patients who used either the placebo gel or the hyaluronic acid gel