29 research outputs found
Tumor surveillance by circulating microRNAs: a hypothesis
Get PDFA growing body of experimental evidence supports the diagnostic relevance of circulating microRNAs in various diseases including cancer. The biological relevance of circulating microRNAs is, however, largely unknown, particularly in healthy individuals. Here, we propose a hypothesis based on the relative abundance of microRNAs with predominant tumor suppressor activity in the blood of healthy individuals. According to our hypothesis, certain sets of circulating microRNAs might function as a tumor surveillance mechanism exerting continuous inhibition on tumor formation. The microRNA-mediated tumor surveillance might complement cancer immune surveillance
An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets
Get PDFmiR-144 suppresses the proliferation and metastasis of hepatocellular carcinoma by targeting E2F3
No full textmiR-126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9
No full textRETRACTED ARTICLE: Downregulation of miR-133b/miR-503 acts as efficient prognostic and diagnostic factors in patients with osteosarcoma and these predictor biomarkers are correlated with overall survival
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Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer: A 10-year follow-up study
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MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells
No full textRETRACTED ARTICLE: RNAi targeting CXCR4 inhibits proliferation and invasion of esophageal carcinoma cells
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