Influence of short-term dietary measures on dioxin concentrations in human milk.

Breast-feeding may expose infants to high levels of toxic chlorinated dioxins. To diminish intake of these lipophilic compounds by the baby, two diets were tested for their ability to reduce concentrations of dioxins in human milk. The diets were a low-fat/high- carbohydrate/low-dioxin diet. (about 20% of energy intake derived from fat) and a high fat /low-carbohydrate/low-dioxin diet. These diets were tested in 16 and 18 breast-feeding women, respectively. The test diets were followed for 5 consecutive days in the fourth week after delivery. Milk was sampled before and at the end of the dietary regimen, and dioxin concentrations and fatty acid concentrations were determined. Despite significant influences of these diets on the fatty acid profiles, no significant influence on the dioxin concentrations in breast milk could be found. We conclude that short-term dietary measures will not reduce dioxin concentration in human milk

Automatic classification of focal liver lesions based on clinical DCE-MR and T2-weighted images:a feasibility study

Focal liver lesion classification is an important part of diagnostics. In clinical practice, T2-weighted (T2W) and dynamic contrast enhanced (DCE) MR images are used to determine the type of lesion. For automatic liver lesion classification only T2W images are exploited. In this feasibility study, a multi-modal approach for automatic lesion classification of five lesion classes (adenoma, cyst, haemangioma, HCC, and metastasis) is studied. Features are derived from four sets: (A) non-corrected, and (B) motion corrected DCE-MRI, (C) T2W images, and (D) B+C combined, originating from 43 patients. An extremely randomized forest is used as classifier. The results show that motion corrected DCE-MRI features are a valuable addition to the T2W features, and improve the accuracy in discriminating benign and malignant lesions, as well as the classification of the five lesion classes. The multimodal approach shows promising results for an automatic liver lesion classification

INFLUENCE OF SHORT-TERM DIETARY MEASURES ON DIOXIN CONCENTRATIONS IN HUMAN-MILK

Breast-feeding may expose infants to high levels of toxic chlorinated dioxins. To diminish intake of these lipophilic compounds by the baby, two diets were tested for their ability to reduce concentrations of dioxins in human milk. The diets were a low-fat/high-carbohydrate/low-dioxin diet (about 20% of energy intake derived from fat) and a high-fat/low-carbohydrate/low-dioxin diet. These diets were rested in 16 and 18 breast-feeding women, respectively. The test diets were followed for 5 consecutive days in the fourth week after delivery. Milk was sampled before at the end of the dietary regimen, and dioxin concentrations and fatty acid concentrations were determined. Despite significant influences of these diets on the fatty acid profiles, no significant influence on the dioxin concentrations in breast milk could be found. We conclude that short-term dietary measures will not reduce dioxin concentrations in human milk

INFLUENCE OF SHORT-TERM DIETARY MEASURES ON DIOXIN CONCENTRATIONS IN HUMAN-MILK

Breast-feeding may expose infants to high levels of toxic chlorinated dioxins. To diminish intake of these lipophilic compounds by the baby, two diets were tested for their ability to reduce concentrations of dioxins in human milk. The diets were a low-fat/high-carbohydrate/low-dioxin diet (about 20% of energy intake derived from fat) and a high-fat/low-carbohydrate/low-dioxin diet. These diets were rested in 16 and 18 breast-feeding women, respectively. The test diets were followed for 5 consecutive days in the fourth week after delivery. Milk was sampled before at the end of the dietary regimen, and dioxin concentrations and fatty acid concentrations were determined. Despite significant influences of these diets on the fatty acid profiles, no significant influence on the dioxin concentrations in breast milk could be found. We conclude that short-term dietary measures will not reduce dioxin concentrations in human milk