10 research outputs found
Identification of novel KIF11 mutations in patients with familial exudative vitreoretinopathy and a phenotypic analysis
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Targeting BRAF in Pediatric Brain Tumors
- Author
- Publication venue
- 'American Society of Clinical Oncology (ASCO)'
- Publication date
- Field of study
Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent
- Author
- AA Aly
- AH Halawa
- AN Izmest’ev
- AV Ivachtchenko
- D Falke
- H Culakova
- H Iranneja
- HB El-Nassan
- HI Ali
- I Kim
- K Sztanke
- KC Goh
- KJ Curran
- L Crespin
- L Yurttaş
- M Abd El-Moneim
- M Bakavoli
- M Khoshneviszadeh
- MB Tollefson
- OI Kiselev
- P Ruanpanun
- R Kumar
- R Kumar
- RM Abdel-Rahman
- RM Abdel-Rahman
- RW Sidwell
- S Abraham
- S El-Kalyoubi
- S Schenone
- S Youssif
- Samar A. El-Kalyoubi
- T Mosmann
- T Nagamatsu
- T Nagamatsu
- TR Walters
- U Sarkar
- V Ludovic
- VL Rusinov
- WA Creasey
- Yu Bulychev
- Z Karczmarzyk
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
First-in-human phase 1 study of filanesib (ARRY-520), a kinesin spindle protein inhibitor, in patients with advanced solid tumors
- Author
- A Blangy
- A Chari
- A Janssen
- B Zhang
- BJ Tunquist
- BM Stern
- D Huszar
- Dale Roseberry
- DR Drummond
- Edward A. Sausville
- EJ Wojcik
- HB El-Nassan
- Heidi M. Simmons
- Jennifer Schreiber
- JJ Shah
- JT Opferman
- JT Opferman
- Judith A. Carter
- Kevin Litwiler
- Lindsay Casetta
- M Schmidt
- Mieke Ptaszynski
- MR Miglarese
- Patricia M. LoRusso
- PG Morris
- Priscila H. Goncalves
- R Sakowicz
- R Woessner
- RD Vale
- RD Woessner
- S Derenne
- S Lonial
- Selena Rush
- U Vijapurkar
- V Sarli
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cells
- Author
- A Castillo
- A Siddiqa
- AI Marcus
- Anna Giuffrida
- AP Enos
- BC Guido
- Bernardina Milana
- C Monte De
- C Muller
- DL Hershman
- EJ Wojcik
- F Iuliis De
- F Iuliis De
- Francesca De Iuliis
- Gerardo Salerno
- H Asanuma
- H Asraf
- H Wang
- HB El-Nassan
- HL Gomez
- I Gasnereau
- I Leizerman
- Ida Silvestri
- JW Purcell
- L Lad
- Ludovica Taglieri
- ND Xing
- O Rath
- PM Lo Russo
- R Nakai
- Sabrina Giantulli
- Simone Carradori
- SM Lens
- SP Blagden
- Susanna Scarpa
- TJ Mitchison
- TM Beer
- TU Mayer
- V Sarli
- WM Sikov
- WT Silkworth
- Y Li
- YG Lv
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Mitotic Slippage and Expression of Survivin Are Linked to Differential Sensitivity of Human Cancer Cell-Lines to the Kinesin-5 Inhibitor Monastrol
- Author
- A Blangy
- A Castillo
- A Gerson-Gurwitz
- A Gerson-Gurwitz
- A Goulet
- AM Saunders
- AP Enos
- AS Kashina
- C Thiede
- CH Cheung
- CH Topham
- CW Lee
- D Grossman
- D Grossman
- DA Scudiero
- DC Altieri
- DJ Sharp
- DM Duhl
- DM Gordon
- DM Roof
- DW Meek
- EJ Wojcik
- EP Sablin
- FJ Kull
- GM Hansen
- HB El-Nassan
- Hila Asraf
- I Hagan
- I Leizerman
- I Touitou
- IC Hsu
- JD Orth
- KS Chan
- L Gheber
- Larisa Gheber
- LC Kapitein
- M Carmena
- M Mobahat
- M Pocard
- MA Hoyt
- Michal Hershfinkel
- N Movshovich
- NJ Ganem
- PA Muller
- PA Tang
- PR Andreassen
- Qiliang Cai
- R Avunie-Masala
- Rachel Avunie-Masala
- RE Ostlund Jr.
- SM Lens
- T Matozaki
- TF Burns
- TJ Mitchison
- TM Beer
- TU Mayer
- V Fridman
- V Fridman
- V Sarli
- VK Jenkins
- WB Isaacs
- WT Silkworth
- YC Lin-Lee
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Clinical Trials of Mitotic Kinesin Inhibitors
- Author
- A Canta
- A-K Souid
- AJ Windebank
- B Drewinko
- B Escudier
- B Owens
- BG Blair
- C Greenman
- C Muller
- CE Gee
- CW Lee
- D Sun
- DL Wheeler
- E Koller
- E Komlodi-Pasztor
- E Komlodi-Pasztor
- G Andres
- H Carol
- HA Burris III
- HB El-Nassan
- HJ Khoury
- HL Gomeza
- HM Kantarjian
- IB Weinstein
- IB Weinstein
- IB Weinstein
- IB Weinstein
- J Tabernero
- J Zheng
- JF Gerecitano
- JJ Knox
- JN Bruce
- JR Infante
- JR Jackson
- JW Purcell
- K Holen
- KD Holen
- KM Gifford
- KW Wood
- LH Hartwell
- M Arnedos
- M Liu
- M Poot
- ME Gorre
- MK Tuxen
- O Rath
- PA Tang
- PG Morris
- R Rosell
- R Sakowicz
- R Yamaguchi
- RT Lee
- S Ding
- S Kobayashi
- S Morgan
- S Valensin
- SF Bunting
- SK Talapatra
- SP Blagden
- T Scholzen
- TJ Mitchison
- TM Beer
- TU Mayer
- V Chung
- W Pao
- WG Kaelin
- WH McBride
- Z Lidar
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Kinesin spindle protein inhibitors in cancer: a patent review (2008 – present)
- Author
- Abualhasan MN
- Barsanti PA
- Basso AD
- Beer TM
- Brier S
- Carol H
- Cheng Jiang
- Cole SP
- Cox CD
- DeBonis S
- Ding S
- El-Nassan HB
- Fu RG
- Gartner M
- Hayashi N
- Heald R
- Hotha S
- Jackson JR
- Jiang C
- Jiang C
- Jiang C
- Jiang C
- Jiang C
- Johnson RK
- Kaan HYK
- Kaan HYK
- Kaan HYK
- Khoury HJ
- Kim KH
- Klein E
- Knigh SD
- Lahue BR
- Liu F
- Liu F
- Liu M
- Liu M
- Luo L
- Masuda A
- Matsuno K
- Matsuno K
- Mayer TU
- Nagarajan S
- Ogo N
- Oishi S
- Parrish CA
- Paull KD
- Prokopcov H
- Purcell JW
- Qidong You
- Rodriguez D
- Rowinsky EK
- Sarli V
- Shimizu M
- Shimizu M
- Skoufias DA
- Souid A
- Sunder-Plassmann S
- Svetlik J
- Takeuchi T
- Tang PA
- Wang F
- Woessner R
- Wood KW
- Xiao S
- Yang L
- Zee-Cheng KY
- Zhang B
- Zhang Y
- Publication venue
- 'Informa Healthcare'
- Publication date
- Field of study
Chemical, Target, and Bioactive Properties of Allosteric Modulation
- Author
- A Bender
- A Bender
- A Christopoulos
- A Gaulton
- A Harmar
- A Liaw
- AA Jensen
- AA Russo
- AC Cheng
- AL Hopkins
- AL Hopkins
- Anna Gaulton
- BB Fredholm
- BW Matthews
- C Abad-Zapatero
- C Abad-Zapatero
- C Knox
- C Strobl
- C Strobl
- D Brown
- D Guo
- D Rogers
- DA Sykes
- Dennis R. Livesay
- DP Brazil
- E De Clercq
- EE Bolton
- F Bacon
- F Wang
- FA Kruger
- Gerard J. P. van Westen
- GG Holz
- GJP Van Westen
- GJP Van Westen
- GJP Van Westen
- GM Keseru
- H Link
- HB El-Nassan
- J Besnard
- J Brognard
- J Kniazeff
- JA Lewis
- JE Lindsley
- JM Stockton
- JNC Kew
- John P. Overington
- JP Overington
- JP Pin
- JR Lane
- KA Jacobson
- KH Bleicher
- LT May
- M Abualhasan
- M Heinemann
- M Vilums
- MJ Keiser
- MM Rubin
- MR Arkin
- MR Rubin
- MT McDermot
- NM Goodey
- P Imming
- P Jeffrey Conn
- PD Jeffrey
- PG Baraldi
- Q Wang
- R Mannhold
- R Narlawar
- R Pauwels
- RC Glen
- RO Dror
- S Betzi
- S Tuèek
- SRJ Hoare
- T Kenakin
- T Liu
- W Soudijn
- X Li
- Y Hu
- Y Mehellou
- Z Fang
- Z Huang
- Z-G Gao
- ZJ Reitman
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Targeted Therapies in Melanoma
- Author
- A Ahn
- A Elsas van
- A Hauschild
- A Hauschild
- A Kauffmann
- A Platz
- A Sharma
- AE Russo
- AM Grimaldi
- AM Menzies
- AY Shull
- B Bressac-de-Paillerets
- BC Bastian
- BF Cole
- C Bertolotto
- C Bertolotto
- C Jhappan
- C Wellbrock
- CA Pratilas
- CJ Hussussian
- D Fanale
- DB Solit
- DG Perez
- DT Alexandrescu
- E Edlundh-Rose
- E Greenberg
- E Hodis
- E Romano
- FS Hodi
- FS Hodi
- FS Hodi
- G Bollag
- G Della Vittoria Scarpati
- GS Falchook
- GV Long
- GV Long
- H Davies
- H Nishimura
- H Tsao
- H Yang
- HB El-Nassan
- I Yeh
- IV Fedorenko
- J Caramel
- J Guo
- J Liu
- J Villanueva
- JA Curtin
- JA Curtin
- JA Ellerhorst
- JA Sosman
- JL Riley
- JM Kirkwood
- JM Shields
- JM Stahl
- JM Stahl
- JR Brahmer
- JT Huntington
- K Margolin
- K Margolin
- K Omholt
- K Omholt
- K Wyman
- K Young
- KB Kim
- KG Griewank
- KH Paraiso
- KP Boyd
- KT Flaherty
- KT Flaherty
- KT Flaherty
- KT Flaherty
- KT Flaherty
- KV Bhatt
- L Zuo
- LA Kottschade
- LH Palavalli
- M Jafari
- M Kortylewski
- M Krauthammer
- M Kunz
- MB Atkins
- MC Fargnoli
- MF Berger
- MG Rughani
- MR Middleton
- NE Thomas
- NG Rao
- NL Schoenewolf
- O Hamid
- P Ghiorzo
- P Ghosh
- P Madureira
- PA Ascierto
- PA Ascierto
- PB Chapman
- PI Poulikakos
- PM Lorusso
- PM Pollock
- R Anforth
- R Busca
- R Dummer
- R Kainthla
- R Moos von
- R Nazarian
- RA Sturm
- RD Carvajal
- RJ Sullivan
- RR Kudchadkar
- RS Dronca
- RV Parry
- S Bhatia
- S Caramuta
- S Ugurel
- S Wilhelm
- S Yokoyama
- SA Rosenberg
- SL Topalian
- SM Oba-Shinjo
- SM Wilhelm
- T Iida
- T Strub
- TD Prickett
- VP Grignol
- X Wei
- Y Chudnovsky
- Y Ishida
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study