Statistical Ensembles with Fluctuating Extensive Quantities

We suggest an extension of the standard concept of statistical ensembles. Namely, we introduce a class of ensembles with extensive quantities fluctuating according to an externally given distribution. As an example the influence of energy fluctuations on multiplicity fluctuations in limited segments of momentum space for a classical ultra-relativistic gas is considered.Comment: 4 pages, 2 figure

Multiplicity Fluctuations in Limited Segments of Momentum Space in Statistical Models

Multiplicity fluctuations in limited segments of momentum space are calculated for a classical pion gas within the statistical model. Results for the grand canonical, canonical, and micro-canonical ensemble are obtained, compared and discussed. We demonstrate that even in the large volume limit correlations between macroscopic subsystems due to energy and momentum conservation persist. Based on the micro-canonical formulation we make qualitative predictions for the rapidity and transverse momentum dependence of multiplicity fluctuations. The resulting effects are of similar magnitude as the predicted enhancement due to a phase transition from a quark-gluon plasma to a hadron gas phase, or due to the critical point of strongly interacting matter, and qualitatively agree with recently published preliminary multiplicity fluctuation data of the NA49 SPS experiment.Comment: 23 pages, 4 figure

Viscosity in the excluded volume hadron gas model

The shear viscosity $\eta$ in the van der Waals excluded volume hadron-resonance gas model is considered. For the shear viscosity the result of the non-relativistic gas of hard-core particles is extended to the mixture of particles with different masses, but equal values of hard-core radius r. The relativistic corrections to hadron average momenta in thermal equilibrium are also taken into account. The ratio of the viscosity $\eta$ to the entropy density s is studied. It monotonously decreases along the chemical freeze-out line in nucleus-nucleus collisions with increasing collision energy. As a function of hard-core radius r, a broad minimum of the ratio $\eta/s\approx 0.3$ near $r \approx 0.5$ fm is found at high collision energies. For the charge-neutral system at $T=T_c=180$ MeV, a minimum of the ratio $\eta/s\cong 0.24$ is reached for $r\cong 0.53$ fm. To justify a hydrodynamic approach to nucleus-nucleus collisions within the hadron phase the restriction from below, $r~ \ge ~0.2$ fm, on the hard-core hadron radius should be fulfilled in the excluded volume hadron-resonance gas.Comment: 12 pages, 3 figure

Particle number fluctuations in nuclear collisions within excluded volume hadron gas model

The multiplicity fluctuations are studied in the van der Waals excluded volume hadron-resonance gas model. The calculations are done in the grand canonical ensemble within the Boltzmann statistics approximation. The scaled variances for positive, negative and all charged hadrons are calculated along the chemical freeze-out line of nucleus-nucleus collisions at different collision energies. The multiplicity fluctuations are found to be suppressed in the van der Waals gas. The numerical calculations are presented for two values of hard-core hadron radius, $r=0.3$ fm and 0.5 fm, as well as for the upper limit of the excluded volume suppression effects.Comment: 19 pages, 4 figure

Preclinical Research into Basic Mechanisms of Radiation-Induced Heart Disease

Radiation-induced heart disease (RIHD) is a potentially severe side effect of radiotherapy of thoracic and chest wall tumors if all or part of the heart was included in the radiation field. RIHD presents clinically several years after irradiation and manifestations include accelerated atherosclerosis, pericardial and myocardial fibrosis, conduction abnormalities, and injury to cardiac valves. There is no method to prevent or reverse these injuries when the heart is exposed to ionizing radiation. This paper presents an overview of recent studies that address the role of microvascular injury, endothelial dysfunction, mast cells, and the renin angiotensin system in animal models of cardiac radiation injury. These insights into the basic mechanisms of RIHD may lead to the identification of targets for intervention in this late radiotherapy side effect

Forward-backward correlations in nucleus-nucleus collisions: baseline contributions from geometrical fluctuations

We discuss the effects of initial collision geometry and centrality bin definition on correlation and fluctuation observables in nucleus-nucleus collisions. We focus on the forward-backward correlation coefficient recently measured by the STAR Collaboration in Au+Au collisions at RHIC. Our study is carried out within two models: the Glauber Monte Carlo code with a `toy' wounded nucleon model and the hadron-string dynamics (HSD) transport approach. We show that strong correlations can arise due to averaging over events in one centrality bin. We, furthermore, argue that a study of the dependence of correlations on the centrality bin definition as well as the bin size may distinguish between these `trivial' correlations and correlations arising from `new physics'.Comment: 12 pages, 6 figure

Enhanced Anandamide Plasma Levels in Patients with Complex Regional Pain Syndrome following Traumatic Injury: A Preliminary Report

The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may develop following injuries of the extremities. The pathogenesis of this syndrome is not clear; however, it includes complex interactions between the nervous and the immune system resulting in chronic inflammation, pain and trophic changes. This interaction may be mediated by chronic stress which is thought to activate the endogenous cannabinoid (endocannabinoid) system (ECS). We conducted an open, prospective, comparative clinical study to determine plasma level of the endocannabinoid anandamide by high-performance liquid chromatography and a tandem mass spectrometry system in 10 patients with CRPS type I versus 10 age- and sex-matched healthy controls. As compared to healthy controls, CRPS patients showed significantly higher plasma concentrations of anandamide. These results indicate that the peripheral ECS is activated in CRPS. Further studies are warranted to evaluate the role of the ECS in the limitation of inflammation and pain. Copyright (C) 2009 S. Karger AG, Base