Ein Beitrag zur Optimierung der Windenergienutzung - einige Beispiele aegyptischer und deutscher Standorte

Die vorliegende Dissertation liefert einen Beitrag zur Windenergienutzung in Aegypten. Sie enthaelt folgende Kapitel: Windkraft als regenerative Energiequelle, Wind-Klimadaten Aegyptens, energetische Bewertung der Windenergienutzung, Ergebnisse der Nutzung und Vergleich der verschiedenen Windkraftanlagen, Empfehlungen. (HW)The present dissertation makes a contribution to wind energy utilisation in Egypt. It contains the following chapters: Wind energy as a renewable energy source; data on wind and climate in Egypt; energetic valuation of wind energy utilisation; results of utilisation and comparison of different wind energy plants; recommendations. (HW)SIGLEAvailable from TIB Hannover: H94B868 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

An experimental study on improvement of Savonius rotor performance

For solving the world energy problem and the bad effect of conventional sources of energy on environment, great attention allover the world is paid towards the use of renewable energy sources. Special interest is paid towards wind energy because of its competitively. Savonius rotor is a vertical axis wind turbine which is characterized as cheaper, simpler in construction and low speed turbine. This makes it suitable for generating mechanical energy in many countries especially in Egypt. In this work different geometries of Savonius wind turbine are experimentally studied in order to determine the most effective operation parameters. It was found that, the two blades rotor is more efficient than three and four ones. The rotor with end plates gives higher efficiency than those of without end plates. Double stage rotors have higher performance compared to single stage rotors. The rotors without overlap ratio (β) are better in operation than those with overlap. The results show also that the power coefficient increases with rising the aspect ratio (α). The conclusions from the measurements of the static torque for each rotor at different wind speeds verify the above summarized results of this work

Therapeutic activity of sour orange albedo extract and abundant flavanones loaded silica nanoparticles against acrylamide-induced hepatotoxicity

The current research aims to demonstrate the therapeutic effect of sour orange albedo extract (SOAE) and two flavanones loaded-tetraethylorthosilicate (TEOS) using sol-gel technique, in adose100 mg/kg body weight taken orally or45 days against acrylamide (ACR)toxicity in rats. This was achieved through measuring the activities of specific biochemical parameters related to liver functions in tissue of ACR intoxicated rats as compared to normal one. Liver functions included alanine and aspartate aminotransferases, antioxidants and oxidative stress biomarkers; superoxide dismutase, catalase, glutathione and lipid peroxide (malondialdehyde, MDA). Moreover, histological examination of liver was performed to confirm the biochemical findings. The present results clearly indicated disturbances in all biochemical parameters, such as increase in the liver function enzyme activities and MDA level. Results of ATPase enzyme activities revealed significant decrease in ACR intoxicated rats and liver biomarker enzymes declared significant decrease. On the other hand, treatment of intoxicated rats with the previous different nano-particles natural product demonstrated improvement in all biochemical parameters under investigation. Keywords: Sour orange albedo, Flavanones, acrylamide, Nanocomposites, Liver biochemical parameters, Histopatholog

A new cost-effectiveness modelling approach in chronic heart failure with reduced ejection fraction - PCV118

Objectives: As new therapies for chronic heart failure with reduced ejection fraction (HFrEF) emerge, health technology assessments (HTAs) will require cost-effectiveness analyses to inform decision making. The objective was to develop a model framework for evaluating the cost-effectiveness of LCZ696, a novel oral therapy proposed for the treatment of HFrEF. Methods: A systematic literature review was performed. Searches were conducted in MEDLINE, EMBASE, EconLit, and Cochrane Library databases, with supplementary hand searching of conferences and HTA websites. Of 63 distinct analyses identified, 33 used decision-analytic models. Structures were most commonly described as Markov models (n=27), but methods employed were heterogeneous. The health states most frequently employed were ‘alive’ and ‘dead’, with outcomes such as hospitalization or New York Heart Association (NYHA) class distribution most commonly considered within the ‘alive’ state. Results: A 2-state Markov model with ‘alive’ and ‘dead’ states was developed using three multivariate regression models to predict the risks of mortality, hospitalisation and the trajectory of health-related quality of life over time within the ‘alive’ state. NYHA class was not used as a basis for health states, as the extrapolation of clinical improvements beyond the observed data was considered clinically implausible. Parametric survival models, negative binomial models and multilevel models are used to predict mortality, hospitalisation, and HRQL, respectively, allowing extrapolation to a lifetime time horizon. The model of HRQL attempts to capture the effects of baseline characteristics, hospitalisation, adverse events and time on EQ-5D. Clinical experts were consulted to validate the regression models and their respective predictions. Conclusions: The new framework employs similar methods to decision analytic models developed previously in heart failure, however models health-related quality of life as a function of time directly, thereby providing a parsimonious approach with improved clinical plausibility compared to other model structures in the literature