65 research outputs found
ALLYLIC STEROID ALCOHOLS. I. STRUCTURES OF THE PRODUCTS RESULTING FROM 7-HYDROXYCHOLESTEROL IN THE MEDIUM OF METHANOL-HYDROCHLORIC ACID.
A Rare Super-Unstable Hemoglobin Variant, Hb Monroe [β30(B12)Arg→Thr], Found in Two Myanmar Children
During the making of a precise molecular diagnosis of blood from transfusion dependent anemic patients in the Union of Myanmar by the PCR-sequencing technique, we encountered two Myanmar children (My-194 and My-201) with a rare abnormal hemoglobin, Hb Monroe [β30(B12)Arg→Thr], which causes β^0-thalassemia due to missplicing in the course of mRNA processing. One of the children, My-194, was a compound heterozygote for Hb Monroe and a thalassemia mutation of βIVS I-5 G→C, who had a condition of severeβ^+-thalassemia resembling a β^0-thalassemia, while the other, My-201, a homozygote for Hb Monroe. However, Hb analyses of My-194 with IEF and DEAE-HPLC revealed a normal pattern, suggesting that it may be due to blood transfusion. Hb analyses of My-201 showed the presence of Hb A to be about 0%, with Hb F being the main Hb component, suggesting that in this case Hb F instead of Hb A may be produced as the main Hb
ALLYLIC STEROID ALCOHOLS. Ⅱ. METHOXYLATION OF THE EPIMERIC 3-HYDROXYCHOLEST-4-ENES IN THE MEDIUM OF METHANOL-HYDROCHLORIC ACID.
Molecular Aspects of Transfusion Dependent Thalassemic Children in Myanmar : Analysis of Common β-Thalassemia in Myanmar by Amplification Refractory Mutation System (ARMS)
Prevalence of Hemoglobin E Among the Children Taking Regular Blood Transfusion at the Day Care Room, Yangon Children Hospital, Myanmar
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