Human capital, higher education and graduate migration: an analysis of Scottish and Welsh students

In this paper we model the sequential migration behaviour of some 76,000 Scottish and Welsh students, from their domicile location to the location of their higher education and on to their employment location. We employ a probit model methodology to analyse the choice of the location of the university attended, whether inside or outside of Scotland or Wales. Then, within a GIS framework we estimate migration-on migration correlations and elasticities in order to identify the mobility effects of human-capital acquisition. Our results confirm the DaVanzo hypothesis that subsequent migration is related to previous migration, and also the Sjaastad-Becker hypothesis that higher human capital individuals are more geographically mobile. However, there are institutional differences between the two countries which mean that but the mobility effects of human-capital acquisition have to be interpreted carefully in the light of other economic, geographic and social influences

Effects of CCR5-Δ 32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data

The burgeoning information on the human genome creates opportunities and challenges for studies of disease associations. Because genetic differences often produce modest effects, many patients must be studied to reach definitive conclusions. In the absence of a single large study, meta-analysis of individual-patient data (1 - 3) from smaller studies offers a way to assemble an adequate sample size. This approach is based on a unifying protocol that has standardized analytic definitions. When the protocol is applied to data contributed by most investigators working in a field, this method can provide more convincing results than a simple pooling of data or a meta-analysis of published reports (3). A meta-analysis of individual-patient data is also superior to a meta-analysis of published reports for examining differences in reported results