29 research outputs found
Long COVID and cardiovascular disease: a prospective cohort study
- Author
- Abel K.
- Adamali H.
- Adeloye D.
- Adeyemi O.
- Adrego R.
- Ahmad S.
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- Publication venue
- BMJ
- Publication date
- 27/05/2024
- Field of study
Background
Pre-existing cardiovascular disease (CVD) or cardiovascular risk factors have been associated with an increased risk of complications following hospitalisation with COVID-19, but their impact on the rate of recovery following discharge is not known.
Objectives
To determine whether the rate of patient-perceived recovery following hospitalisation with COVID-19 was affected by the presence of CVD or cardiovascular risk factors.
Methods
In a multicentre prospective cohort study, patients were recruited following discharge from the hospital with COVID-19 undertaking two comprehensive assessments at 5 months and 12 months. Patients were stratified by the presence of either CVD or cardiovascular risk factors prior to hospitalisation with COVID-19 and compared with controls with neither. Full recovery was determined by the response to a patient-perceived evaluation of full recovery from COVID-19 in the context of physical, physiological and cognitive determinants of health.
Results
From a total population of 2545 patients (38.8% women), 472 (18.5%) and 1355 (53.2%) had CVD or cardiovascular risk factors, respectively. Compared with controls (n=718), patients with CVD and cardiovascular risk factors were older and more likely to have had severe COVID-19. Full recovery was significantly lower at 12 months in patients with CVD (adjusted OR (aOR) 0.62, 95% CI 0.43 to 0.89) and cardiovascular risk factors (aOR 0.66, 95% CI 0.50 to 0.86).
Conclusion
Patients with CVD or cardiovascular risk factors had a delayed recovery at 12 months following hospitalisation with COVID-19. Targeted interventions to reduce the impact of COVID-19 in patients with cardiovascular disease remain an unmet need
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- 'Wiley'
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SPLENIC INHIBITORY FACTORS: A ROLE IN HEPATIC REGENERATION? An experimental study of a splenic inhibitory factor influencing hepatic regeneration.
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- 'Wiley'
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Synovial sarcoma of the head and neck a report of 3 cases
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Intercomparison on PD calibrators and PD instruments
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Lactic Fermentation of Media Containing High Concentrations of Yeast Extracts
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Dermatofibrosarcoma protuberans: a clinicopathological and immunohistochemical study with a review of the literature
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- 'Wiley'
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The rhabdomyosarcoma with regard to age, sex, localization, pathological anatomy, and prognosis
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- W. Rhomberg
- W.W. Sutow
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1978
- Field of study