29 research outputs found
Moving glass phase of driven lattices
We study periodic lattices, such as vortex lattices, driven by an external
force in a random pinning potential. We show that effects of static disorder
persist even at large velocity. It results in a novel moving glass state with
topological order analogous to the static Bragg glass. The lattice flows
through well-defined, elastically coupled, {\it % static} channels. We predict
barriers to transverse motion resulting in finite transverse critical current.
Experimental tests of the theory are proposed.Comment: Revised version, shortened, 8 pages, REVTeX, no figure
Topological Defects, Orientational Order, and Depinning of the Electron Solid in a Random Potential
We report on the results of molecular dynamics simulation (MD) studies of the
classical two-dimensional electron crystal in the presence disorder. Our study
is motivated by recent experiments on this system in modulation doped
semiconductor systems in very strong magnetic fields, where the magnetic length
is much smaller than the average interelectron spacing , as well as by
recent studies of electrons on the surface of helium. We investigate the low
temperature state of this system using a simulated annealing method. We find
that the low temperature state of the system always has isolated dislocations,
even at the weakest disorder levels investigated. We also find evidence for a
transition from a hexatic glass to an isotropic glass as the disorder is
increased. The former is characterized by quasi-long range orientational order,
and the absence of disclination defects in the low temperature state, and the
latter by short range orientational order and the presence of these defects.
The threshold electric field is also studied as a function of the disorder
strength, and is shown to have a characteristic signature of the transition.
Finally, the qualitative behavior of the electron flow in the depinned state is
shown to change continuously from an elastic flow to a channel-like, plastic
flow as the disorder strength is increased.Comment: 31 pages, RevTex 3.0, 15 figures upon request, accepted for
publication in Phys. Rev. B., HAF94MD
Commensurate and Incommensurate Vortex Lattice Melting in Periodic Pinning Arrays
We examine the melting of commensurate and incommensurate vortex lattices
interacting with square pinning arrays through the use of numerical
simulations. For weak pinning strength in the commensurate case we observe an
order-order transition from a commensurate square vortex lattice to a
triangular floating solid phase as a function of temperature. This floating
solid phase melts into a liquid at still higher temperature. For strong pinning
there is only a single transition from the square pinned lattice to the liquid
state. For strong pinning in the incommensurate case, we observe a multi-stage
melting in which the interstitial vortices become mobile first, followed by the
melting of the entire lattice, consistent with recent imaging experiments. The
initial motion of vortices in the incommensurate phase occurs by an exchange
process of interstitial vortices with vortices located at the pinning sites. We
have also examined the vortex melting behavior for higher matching fields and
find that a coexistence of a commensurate pinned vortex lattice with an
interstitial vortex liquid occurs while at higher temperatures the entire
vortex lattice melts. For triangular arrays at incommensurate fields higher
than the first matching field we observe that the initial vortex motion can
occur through a novel correlated ring excitation where a number of vortices can
rotate around a pinned vortex. We also discuss the relevance of our results to
recent experiments of colloidal particles interacting with periodic trap
arrays.Comment: 8 figure
Estudo comparativo entre as técnicas de diluição em caldo e diluição em ágar, nos antibiogramas para Candida: a comparative study
Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH): study design and baseline data.
BACKGROUND: The CAPRIE study showed the superiority of clopidogrel over acetylsalicylic acid (ASA) for reducing the combined risk of major atherothrombotic events in patients with recent myocardial infarction (MI), recent ischaemic stroke (IS) or established peripheral arterial disease. The benefit of clopidogrel over ASA is amplified in high-risk patients. Proof of concept for the benefit of clopidogrel in addition to ASA in patients with coronary manifestations of atherothrombosis was provided by the CURE trial. METHODS: MATCH is a randomized, double-blind, placebo-controlled trial that compares clopidogrel and ASA versus clopidogrel alone in high-risk patients with recently symptomatic cerebrovascular disease. Eligible patients have experienced a transient ischaemic attack (TIA) or IS within the last 3 months and have evidence of at least 1 additional risk factor within the last 3 years (prior IS, MI, stable or unstable angina pectoris, diabetes or symptomatic peripheral arterial disease). Patients were randomized to receive ASA 75 mg once daily or placebo, with both groups receiving clopidogrel 75 mg once daily as part of standard therapy. The primary end point is the composite of IS, MI, vascular death and rehospitalization for an acute ischaemic event. The duration of treatment and follow-up is 18 months for each patient. RESULTS: Enrollment was completed in April 2002, with 7,599 patients randomized to receive the study medication. The mean age at randomization was 66 years, and the qualifying event was IS in 78.9% of patients and TIA in 21.1%. The baseline features of the study cohort indicate a population that is at a high risk for atherothrombotic recurrence. CONCLUSION: MATCH is a major ongoing trial that will provide important data on the benefit of clopidogrel and ASA compared with clopidogrel alone for reduction of vascular ischaemic events in patients with recent TIA or IS who are at high risk of atherothrombotic event recurrence