Early Chinese Trade

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Dataset on gene expression in the elderly after Mindfulness Awareness Practice or Health Education Program

It has been reported that relaxation techniques can improve physical health and cognitive function. A number of studies involving different types of relaxation practices showed changes in expression of genes. We investigated the gene expression pattern of a cohort of elderly subjects of Asian descent after weekly (for the first three months) and monthly (for the subsequent six months) intervention. Sixty consenting elderly subjects (aged 60–90 years) with mild cognitive impairment were assigned to either the Mindfulness Awareness Practice (MAP) or Health Education Program (HEP) group in a randomized controlled trial to assess the effectiveness of the programs in preventing further cognitive decline and evaluate the influence on neurological, cellular and biochemical factors. Blood samples were collected before the start of intervention and after nine months for gene expression profiling using Affymetrix Human Genome U133 Plus 2.0 arrays. The dataset is publicly available for further analyses

Next-to-Leading Order Constituent Quark Structure and Hadronic Structure Functions

We calculate the partonic structure of a constituent quark in the Next-to-Leading Order framework. The structure of any hadron can be obtained thereafter using a convolution method. Such a procedure is used to generate the structure function of proton and pion in NLO, neglecting certain corrections to $\Lambda_{QCD}$. It is shown that while the constituent quark structure is generated purely perturbatively and accounts for the most part of the hadronic structure, there is a few percent contributions coming from the nonperturbative sector in the hadronic structure. This contribution plays the key role in explaining the SU(2) symmetry breaking of the nucleon sea and the observed violation of Gottfried sum rule. These effects are calculated. We obtained an Excellent agreement with the experimental data in a wide range of $x=[10^{-6}, 1]$ and $Q^{2}=[0.5, 5000]$ $GeV^{2}$ for the proton structure function. We have also calculated Pion structure and compared it with the existing data. Again, the model calculations agree rather well with the data from experiment.Comment: 32 pages,10 figures, Accepted to publish in Phys. Rev.

Alcohol Consumption Among Older Adults in Primary Care

BACKGROUND: Alcohol misuse is a growing public health concern for older adults, particularly among primary care patients. OBJECTIVES: To determine alcohol consumption patterns and the characteristics associated with at-risk drinking in a large sample of elderly primary care patients. DESIGN: Cross-sectional analysis of multisite screening data from 6 VA Medical Centers, 2 hospital-based health care networks, and 3 Community Health Centers. PARTICIPANTS: Patients, 43,606, aged 65 to 103 years, with scheduled primary care appointments were approached for screening; 27,714 (63.6%) consented to be screened. The final sample of persons with completed screens comprised 24,863 patients. MEASUREMENTS: Quantity and frequency of alcohol use, demographics, social support measures, and measures of depression/anxiety. RESULTS: Of the 24,863 older adults screened, 70.0% reported no consumption of alcohol in the past year, 21.5% were moderate drinkers (1–7 drinks/week), 4.1% were at-risk drinkers (8–14 drinks/week), and 4.5% were heavy (>14 drinks/week) or binge drinkers. Heavy drinking showed significant positive association with depressive/anxiety symptoms [Odds ratio (OR) (95% CI): 1.79 (1.30, 2.45)] and less social support [OR (95% CI): 2.01 (1.14, 2.56)]. Heavy drinking combined with binging was similarly positively associated with depressive/anxiety symptoms [OR (95%): 1.70 (1.33, 2.17)] and perceived poor health [OR (95% CI): 1.27 (1.03, 1.57)], while at-risk drinking was not associated with any of these variables. CONCLUSIONS: The majority of participants were nondrinkers; among alcohol users, at-risk drinkers did not differ significantly from moderate drinkers in their characteristics or for the 3 health parameters evaluated. In contrast, heavy drinking was associated with depression and anxiety and less social support, and heavy drinking combined with binge drinking was associated with depressive/anxiety symptoms and perceived poor health

Light flavor asymmetry of nucleon sea

The light flavor antiquark distributions of the nucleon sea are calculated in the effective chiral quark model and compared with experimental results. The contributions of the flavor-symmetric sea-quark distributions and the nuclear EMC effect are taken into account to obtain the ratio of Drell-Yan cross sections $\sigma^{\mathrm{pD}}/2\sigma^{\mathrm{pp}}$, which can match well with the results measured in the FermiLab E866/NuSea experiment. The calculated results also match the measured $\bar{d}(x)-\bar{u}(x)$ from different experiments, but unmatch the behavior of $\bar{d}(x)/\bar{u}(x)$ derived indirectly from the measurable quantity $\sigma^{\mathrm{pD}}/2\sigma^{\mathrm{pp}}$ by the FermiLab E866/NuSea Collaboration at large $x$. We suggest to measure again $\bar{d}(x)/\bar{u}(x)$ at large $x$ from precision experiments with careful experimental data treatment. We also propose an alternative procedure for experimental data treatment.Comment: 10 pages, 8 figures, final version to appear in EPJ

The elite's collective subjectivities of the history of ethnic politics in Malaysia

Malaysia is one of the multi-ethnic, multi-cultural and multi-religious countries in Southeast Asia. Due to the pluralistic nature of Malaysia, it has a political structure based on ethnic politics. The ethnic preferential policies affected most domains of this country. The objective of this article is to examine the origin and background of ethnic politics in Malaysia. Findings of this study indicate that, ethnic politics originated during the British colonial period, it became a tool used by the Barisan Nasional for the legitimacy of regime. Moreover, ethnic politics in Malaysia today is intertwined with religion. Besides, there is the dilemma of the choice between the interest of certain ethnic group and national interests. However, with the opposition coalition Pakatan Harapan won the election in 9th May, UMNO-led BN lost power and interrupted its 61 years control, which leaves us an interesting topic to think about the future of Malaysian ethnic politics

Making sense of the evolving nature of depression narratives and their inherent conflicts

Originally a psychiatric diagnosis fashioned by Western psychiatry in the 20th Century, depression evolved to encompass varying lineages of discourse and care. This article elucidates some of the current challenges – as well as emerging discourses – influencing the category of depression. Depression-like experiences are shaped by (at times conflicting) subjectivities, claims to knowledge, material realities, social contexts and access to resources. With no unified understanding of the category of ‘depression’ available, lay people, social and neuro scientists, GPs, psychiatrists, talking therapists and pharmaceutical companies all attempt to shape narratives of depression. The current paper focuses on patient narratives about depression – in the context of these wider debates – to better elucidate the ways in which depression discourses are publically developing along varying lines. In conclusion, the paper suggests that we could better conceptualise the resulting ‘depression(s)’ with concepts such as ‘society of mind’ and notions of subjectivity unbounded by individuals