Fish Diversity in Huchharayanakere, Shikaripura, Shivamogga District, Karnataka, India

Fresh water wetlands are fragile ecosystems, which are fast deterioring and shrinking due to manmade activities. The fish composition of Huchharayanakere of Shikaripura was studied for a period of twelve months from January to December 2015. The icthyo-faunal diversity of this pond confirmed the occurrence of 13 species of fishes belonging to 5 families. The family Cyprinidae represented by 9 species. Families Anabantidae, Bagridae, Clupeidae and Notopteridae were represented by only a single species. Simultaneously the physico-chemical condition of the water body revealed that water quality is suitable for fish culture. The study of fish fauna of an aquatic body is useful for planning of fisheries development. The pond needs proper management and utilization of this fish wealth and sustainable steps to monitor and conserve the fish health. The present study revealed that Huchharayanakere of Shikaripura harbors wide varieties of fish with economic importance in local and global trade. The study will provide future strategies for development and fish conservation

Mechanism of haematotoxicity induced by phenylhydrazine: a review

This work was carried out to show the effects of phenylhydrazine (PHZ) induced anaemic condition. Anaemic condition is defined as reduction in red blood cells (RBC) than normal number of red blood cells. The anti-anaemic activity can be studied using the changes in haematological parameters (PCV, RBC & Haemoglobin) influenced by PHZ [(40mg/kg p.o.)] in rats. PHZ, a potent chemical that causes different effects on different tissues at several levels. Administration of PHZ causes haemolytic anaemia, genotoxic effects and rose in iron absorption in spleen, liver and duodenum & causes change in iron metabolism. PHZ acts by activating immune response which triggers phagocytosis and also interfere with the binding of erythropoietin (EPO) receptors and further JAK-STAT pathway. PHZ also causes genotoxic effect by forming single strand DNA damage. In view of lipid peroxidation along with the formation of Thiobarbituric acid (TBA)-reactive malonyldialdehyde, it is recommend that PHZ induces anaemia as an outcome of peroxidation of  RBC membrane lipids and this effect may be a upshot of the autoxidation of the drug and the interaction of membrane lipids and oxygen radical

Generalized symmetric nonextensive thermostatistics and q-modified structures

We formulate a convenient generalization of the q-expectation value, based on the analogy of the symmetric quantum groups and q-calculus, and show that the q->q^{-1} symmetric nonextensive entropy preserves all of the mathematical structure of thermodynamics just as in the case of non-symmetric Tsallis statistics. Basic properties and analogies with quantum groups are discussed.Comment: 9 pages, 1 figure. To appear in Mod. Phys. Lett.

PURIFICATION AND BIOCHEMICAL CHARACTERIZATION OF L-AMINO ACID OXIDASE FROM WESTERN REGION INDIAN COBRA (NAJA NAJA) VENOM

Objective: Purification and biochemical characterization of LAAO from western region Indian Cobra (Naja naja) venom.Methods: LAAO was purified from Indian cobra (Naja naja) venom using sequential chromatography on Sephadex G-75 gel filtration followed by Ion exchange on CM-Sephadex C-25 column. Biochemical characterization viz., pH, Temperature, Km and Vmax were determined. Molecular weight of LAAO was determined by electrophoresis. Inhibition of LAAO from cold water extracts of Curcuma zedoria, Curcuma ceasia, Curcuma aromatic, Curcuma longa, Curcuma amada, Cucumis sativus and Benincasa hispida was done.Results: Purified LAAO showed the single band on non reducing SDS-PAGE with approximate molecular weight of 65 kDa. Further biochemical characterization revealed that, LAAO from Naja naja (western region) has an optimum pH of 7.0 and is stable at room Temperature upto 37 °C and showed an optimum enzyme concentration of 4µg/ml and Km 134.1µM and Vmax is 21.87 U/min. Cold water extract of Curcuma ceasia, Curcuma aromatic and Benincasa hispida showed comparatively significant inhibition of LAAO.Conclusion: LAAO has promising therapeutic prospects because of its effects on various biological functions. Variation in snake species and their geographical distribution also contributes to the venom properties such as composition, toxicity level, pharmacological and biological activities. The significant difference in protein profiling leads to substantial lethality among different geographical regions. Thus in this study Indian Cobra (Naja naja) venom from the western region of India was subjected to purification of LAAO and biochemical characterization. Â

Investigation of the crystal structures of n-(4-fluorobenzoyl) benzenesulfonamide and n-(4-fluoro-benzoyl)-4-methylbenzenesulfonamide

The title compound, C26H26N2O7, is a thia­midine derivative. Geometric parameters are in the usual ranges. The crystal packing is stabilized by a classical N—H⋯O hydrogen bond, several weak C—H⋯O hydrogen bonds and a π–π stacking inter­action