Differences in virus receptor for type I and type II feline infectious peritonitis virus.

Feline infectious peritonitis viruses (FIPVs) are classified into type I and type II serogroups. Here, we report that feline aminopeptidase N (APN), a cell-surface metalloprotease on the intestinal, lung and kidney epithelial cells, is a receptor for type II FIPV but not for type I FIPV. A monoclonal antibody (MAb) R-G-4, which blocks infection of Felis catus whole fetus (fcwf-4) cells by type II FIPV, was obtained by immunizing mice with fcwf-4 cells which are highly susceptible to FIPV. This MAb also blocked infection of fcwf-4 cells by type II feline enteric coronavirus (FECV), canine coronavirus (CCV), and transmissible gastroenteritis virus (TGEV). On the other hand, it did not block infection by type I FIPVs. MAb R-G-4 recognized a polypeptide of relative molecular mass 120-130 kDa in feline intestinal brush-border membrane (BBM) proteins. The polypeptide possessed aminopeptidase activity, and the first 15 N-terminal amino acid sequence was identical to that of the feline APN. Feline intestinal BBM proteins and the polypeptide reacted with MAb R-G-4 (feline APN) inhibited the infectivity of type II FIPV, type II FECV, CCV and TGEV to fcwf-4 cells, but did not inhibit the infectivity of type I FIPVs

Giant directional dichroism of terahertz light in resonance with magnetic excitations of the multiferroic oxide BaCo2_2Ge2_2O7_7

We propose that concurrently magnetic and ferroelectric, i.e. multiferroic, compounds endowed with electrically-active magnetic excitations (electromagnons) provide a key to produce large directional dichroism for long wavelengths of light. By exploiting the control of ferroelectric polarization and magnetization in a multiferroic oxide Ba$_2$CoGe$_2$O$_7$, we demonstrate the realization of such a directional light-switch function at terahertz frequecies in resonance with the electromagnon absorption. Our results imply that this hidden potential is present in a broad variety of multiferroics

Partial and macroscopic phase coherences in underdoped Bi2{}_{2}Sr2{}_{2}CaCu2{}_{2}O8+δ{}_{8+{\delta}} thin film

A combined study with use of time-domain pump-probe spectroscopy and time-domain terahertz transmission spectroscopy have been carried out on an underdoped Bi$_2$Sr$_2$CaCu$_2$O$_{8+{\delta}}$ thin film. It was observed that the low energy multi-excitation states were decomposed into superconducting gap and pseudogap. The pseudogap locally opens below $T^*{\simeq}210$ K simultaneously with the appearance of the high-frequency partial pairs around 1.3 THz. With decreasing temperature, the number of the local domains with the partial phase coherence increased and saturated near 100 K, and the macroscopic superconductivity appeared below 76 K through the superconductivity fluctuation state below 100 K. These experimental results indicate that the pseudogap makes an important role for realization of the superconductivity as a precursor to switch from the partial to the macroscopic phase coherence.Comment: Revtex4, 4 pages, 4 figure