14 research outputs found
Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry
Full text linkCompatibility studies between captopril and pharmaceutical excipients used in tablets formulations
No full textCaptopril (CAP) was the first commercially available angiotensine-converting enzyme (ACE) inhibitor. In the anti-hypertensive therapy is considered the selected drug has to be therapeutically effective together with reduced toxicity. CAP is an antihypertensive drug currently being administered in tablet form. In order to investigate the possible interactions between CAP and excipients in tablets formulations, differential scanning calorimetry (DSC) and thermogravimetric (TG) analysis completed by X-ray powder diffraction (XRPD) and Fourier transform infrared spectroscopy (FTIR) were used for compatibility studies. A possible drug-excipient interaction was observed with magnesium stearate by DSC technique
Increased bioavailability of primaquine using poly(ethylene oxide) matrix extended-release tablets administered to beagle dogs
No full textPreparation and characterization of spray-dried gelatin microspheres encapsulating ganciclovir
No full textThermal decomposition kinetics and compatibility studies of primaquine under isothermal and non-isothermal conditions
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Investigation of the Dissolution Profile of Gliclazide Modified-Release Tablets Using Different Apparatuses and Dissolution Conditions
No full textCompatibility studies between captopril and pharmaceutical excipients used in tablets formulations
No full textNew Perspectives for Fixed Dose Combinations of Poorly Water-Soluble Compounds: a Case Study with Ezetimibe and Lovastatin
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