Nuclear fission: The "onset of dissipation" from a microscopic point of view

Semi-analytical expressions are suggested for the temperature dependence of those combinations of transport coefficients which govern the fission process. This is based on experience with numerical calculations within the linear response approach and the locally harmonic approximation. A reduced version of the latter is seen to comply with Kramers' simplified picture of fission. It is argued that for variable inertia his formula has to be generalized, as already required by the need that for overdamped motion the inertia must not appear at all. This situation may already occur above T=2 MeV, where the rate is determined by the Smoluchowski equation. Consequently, comparison with experimental results do not give information on the effective damping rate, as often claimed, but on a special combination of local stiffnesses and the friction coefficient calculated at the barrier.Comment: 31 pages, LaTex, 9 postscript figures; final, more concise version, accepted for publication in PRC, with new arguments about the T-dependence of the inertia; e-mail: [email protected]

Exact Superpotentials, Theories with Flavor and Confining Vacua

In this paper we study some interesting properties of the effective superpotential of N=1 supersymmetric gauge theories with fundamental matter, with the help of the Dijkgraaf--Vafa proposal connecting supersymmetric gauge theories with matrix models. We find that the effective superpotential for theories with N_f fundamental flavors can be calculated in terms of quantities computed in the pure (N_f=0) gauge theory. Using this property we compute in a remarkably simple way the exact effective superpotential of N=1 supersymmetric theories with fundamental matter and gauge group SU(N_c), at the point in the moduli space where a maximal number of monopoles become massless (confining vacua). We extend the analysis to a generic point of the moduli space, and show how to compute the effective superpotential in this general case.Comment: 16 pages, no figure

Symplectic Quantization of Open Strings and Noncommutativity in Branes

We show how to translate boundary conditions into constraints in the symplectic quantization method by an appropriate choice of generalized variables. This way the symplectic quantization of an open string attached to a brane in the presence of an antisymmetric background field reproduces the non commutativity of the brane coordinates.Comment: We included a comparison with previous results obtained from Dirac quantization, emphasizing the fact that in the symplectic case the boundary conditions, that lead to the non commutativity, show up from the direct application of the standard method. Version to appear in Phys. Rev.

Cobicistat as a Potential Booster of Ponatinib and Dasatinib Exposure in a CML Patient:A Case Study

The authors present a case of a 57-year-old patient with chronic myeloid leukemia who was treated with ponatinib and subsequently treated with dasatinib. The patient showed a major molecular response; however, the BCR-ABL1 signal increased with low ponatinib and dasatinib trough concentrations. Cobicistat was used as a pharmacokinetic booster to increase ponatinib and dasatinib exposure, as opposed to increasing the dose. However, ponatinib exposure was not sufficiently increased by cobicistat. The peak dasatinib concentration was successfully increased with cobicistat treatment. Dasatinib and cobicistat cotreatment induced a response in BCR-ABL1 PCR signal, was well tolerated, and led to a substantial reduction in drug costs.</p

Low Energy Analyzing Powers in Pion-Proton Elastic Scattering

Analyzing powers of pion-proton elastic scattering have been measured at PSI with the Low Energy Pion Spectrometer LEPS as well as a novel polarized scintillator target. Angular distributions between 40 and 120 deg (c.m.) were taken at 45.2, 51.2, 57.2, 68.5, 77.2, and 87.2 MeV incoming pion kinetic energy for pi+ p scattering, and at 67.3 and 87.2 MeV for pi- p scattering. These new measurements constitute a substantial extension of the polarization data base at low energies. Predictions from phase shift analyses are compared with the experimental results, and deviations are observed at low energies.Comment: 15 pages, 4 figure

AdS_7/CFT_6, Gauss-Bonnet Gravity, and Viscosity Bound

We study the relation between the causality and the positivity of energy bounds in Gauss-Bonnet gravity in AdS_7 background and find a precise agreement. Requiring the group velocity of metastable states to be bounded by the speed of light places a bound on the value of Gauss-Bonnet coupling. To find the positivity of energy constraints we compute the parameters which determine the angular distribution of the energy flux in terms of three independent coefficients specifying the three-point function of the stress-energy tensor. We then relate the latter to the Weyl anomaly of the six-dimensional CFT and compute the anomaly holographically. The resulting upper bound on the Gauss-Bonnet coupling coincides with that from causality and results in a new bound on viscosity/entropy ratio.Comment: 21 page, harvmac; v2: reference adde

Parton picture for the strongly coupled SYM plasma

Deep inelastic scattering off the strongly coupled N=4 supersymmetric Yang-Mills plasma at finite temperature can be computed within the AdS/CFT correspondence, with results which are suggestive of a parton picture for the plasma. Via successive branchings, essentially all partons cascade down to very small values of the longitudinal momentum fraction x and to transverse momenta smaller than the saturation momentum Q_s\sim T/x. This scale Q_s controls the plasma interactions with a hard probe, in particular, the jet energy loss and its transverse momentum broadening.Comment: 4 pages, Talk given at Quark Matter 2008: 20th International Conference on Ultra-Relativistic Nucleus Nucleus Collisions (QM 2008), Jaipur, India, 4-10 Feb 200

Adding Fundamental Matter to ``Chiral Rings and Anomalies in Supersymmetric Gauge Theory''

We consider a supersymmetric U(N) gauge theory with matter fields in the adjoint, fundamental and anti-fundamental representations. As in the framework which was put forward by Dijkgraaf and Vafa, this theory can be described by a matrix model. We analyze this theory along the lines of [F. Cachazo, M. Douglas, N.S. and E. Witten, ``Chiral Rings and Anomalies in Supersymmetric Gauge Theory'' hep-th/0211170] and show the equivalence of the gauge theory and the matrix model. In particular, the anomaly equations in the gauge theory is identified with the loop equations in the matrix model.Comment: 14 page

Reflecting magnons from D7 and D5 branes

We obtain the reflection matrices for the scattering of elementary magnons from certain open boundaries, corresponding to open strings ending on D7 and D5 branes in $AdS_5\times S^5$. In each case we consider two possible orientations for the vacuum state. We show that symmetry arguments are sufficient to determine the reflection matrices up to at most two unknown functions. The D7 reflection matrices obey the boundary Yang Baxter-Equation. This is automatic for one vacuum orientation, and requires a natural choice of ratio between two unknowns for the other. In contrast, the D5 reflection matrices do not obey the boundary Yang Baxter-Equation. In both cases we show consistency with the existent weak and strong coupling results.Comment: 32 pages, 1 figure; v2: added references and minor changes; v3: error in boundary Yang-Baxter equation for D5 reflection matrix note

Phases of N=1 Supersymmetric SO/Sp Gauge Theories via Matrix Model

We extend the results of Cachazo, Seiberg and Witten to N=1 supersymmetric gauge theories with gauge groups SO(2N), SO(2N+1) and Sp(2N). By taking the superpotential which is an arbitrary polynomial of adjoint matter \Phi as a small perturbation of N=2 gauge theories, we examine the singular points preserving N=1 supersymmetry in the moduli space where mutually local monopoles become massless. We derive the matrix model complex curve for the whole range of the degree of perturbed superpotential. Then we determine a generalized Konishi anomaly equation implying the orientifold contribution. We turn to the multiplication map and the confinement index K and describe both Coulomb branch and confining branch. In particular, we construct a multiplication map from SO(2N+1) to SO(2KN-K+2) where K is an even integer as well as a multiplication map from SO(2N) to SO(2KN-2K+2) (K is a positive integer), a map from SO(2N+1) to SO(2KN-K+2) (K is an odd integer) and a map from Sp(2N) to Sp(2KN+2K-2). Finally we analyze some examples which show some duality: the same moduli space has two different semiclassical limits corresponding to distinct gauge groups.Comment: 55pp; two paragraphs in page 19 added to clarify the relation between confinement index and multiplication map index, refs added and to appear in JHEP; Konishi anomaly equations corrected and some comments on the degenerated cases for SO(7) and SO(8) adde