Synthetic, spectroscopic and Antimicrobial activity of mixed ligand of some complexes of symmetrical Schiff base and Nicotinamide

New symmetrical Schiff base ligand (H2L) is prepared via condensation of hydrazine hydrate and 4-hydroxy-3-methoxybenzaldehyde  in ethanol solution at room temperature is reported  . Polydentate  mixed ligand     complexes were obtained from 1:1:1  molar ratio reactions with metal ions and H2L, NA  on reaction with MCl2 .nH2O salt yields complexes corresponding to the formulas [M(L)(NA)2] . All the complexes are air stable and soluble in water and common organic except benzene .All complexes are soluble in dimethyl formamide (DMF)and dimethyl sulfoxide (DMSO) solvent. Comparison of the IR spectra of ligands(H2L) and  (NA)  and there  metal complexes confirm that Schiff base behave as a dibasic tetradentate ligand towards the central metal ion with an ONNO donor sequence  and nicotinamid . behave as unidentate . The ligands and their metal complexes were screened for their antimicrobial activity against four bacteria(gram +ve) and (gram -ve). Keywords: Complexes; Spectral; symmetrical Schiff base Metal complexes ; Antimicrobial activities