1,223 research outputs found

    The CMB Dipole and Circular Galaxy Distribution

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    The validity of Hubble's law defies the determination of the center of the big bang expansion, even if it exists. Every point in the expanding universe looks like the center from which the rest of the universe flies away. In this article, the author shows that the distribution of apparently circular galaxies is not uniform in the sky and that there exists a special direction in the universe in our neighborhood. The data is consistent with the assumption that the tidal force due to the mass distribution around the universe center causes the deformation of galactic shapes depending on its orientation and location relative to the center and our galaxy. Moreover, the cmb dipole data can also be associated with the center of the universe expansion, if the cmb dipole at the center of our supercluster is assumed to be due to Hubble flow. The location of the center is estimated from the cmb dipole data. The direction to the center from both sets of data is consistent and the distance to the center is computed from the cmb dipole data.Comment: 9 pages, 3 figures (10 figure captions), 1 tabl

    Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis

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    Nonstructural proteins of Sindbis virus, nsPl, nsP2, nsP3, and nsP4, as well as intermediate polyproteins, are produced from two precursor polyproteins, Pl23 and Pl234, by a proteolytic enzyme encoded in the C-terminal half of nsP2. We studied the requirements for and the functions of the intermediate and mature processing products for Sindbis virus RNA synthesis by using site-directed mutants which have a defect(s) in processing the 1/2, 2/3, or 3/4 cleavage sites either singly or in various combinations. A mutant defective in cleaving both the 1/2 and 2/3 sites, which makes only uncleavable Pl23 and mature nsP4 as final products, produced 10-3 as much virus as did the wild-type virus after 10 hat 30°C and was nonviable at 40°C. A mutant defective in processing the 2/3 site, which makes nsPl, nsP4, and P23 as well as precursor Pl23, grew 10-1 as efficiently as wild-type virus at 30°C and 10-3 as efficiently at 40°C. Early minus-strand RNA synthesis by these mutants was as efficient as that by wild-type virus, whereas plus-strand RNA synthesis was substantially decreased compared with that by wild-type virus. A mutant defective in processing the 3/4 site was nonviable at either 30 or 40°C. The 3/4 site mutant could be complemented by the mutant unable to cleave either the 1/2 or 2/3 site, which can provide mature nsP4. We interpret these results to signify that (i) mature nsP4 is required for RNA replication, (ii) nsP4 and uncleaved Pl23 function in minus-strand RNA synthesis, and (iii) cleavage of Pl23 is required for efficient plus-strand RNA synthesis. We propose that Sindbis virus RNA replication is regulated by differential proteolysis of Pl23. Early in infection, nsP4 and uncleaved Pl23 form transient minus-strand RNA replication complexes which vanish upon cleavage of Pl23. Later in infection, an elevated level of viral proteinase activity eliminates de novo synthesis of Pl23, and no further synthesis of minus-strand RNA is possible. In contrast, nsP4 and cleavage products from Pl23 form plus-strand RNA replication complexes which are stable and remain active throughout the infection cycle

    Effect of zero energy bound states on macroscopic quantum tunneling in high-Tc superconductor junctions

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    The macroscopic quantum tunneling (MQT) in the current biased high-Tc superconductor Josephson junctions and the effect of the zero energy bound states (ZES) on the MQT are theoretically investigated. We obtained the analytical formula of the MQT rate and showed that the presence of the ZES at the normal/superconductor interface leads to a strong Ohmic quasiparticle dissipation. Therefore, the MQT rate is noticeably inhibited in compared with the c-axis junctions in which the ZES are completely absent.Comment: 4 pages, 1 figure, comment and reference about recent experiment adde

    Competition between singlet and triplet pairings in Na_xCoO_2 yH_2O

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    We discuss the pairing symmetry of a cobaltate superconductor Nax_xCoO2y_2\cdot y H2_2O by adopting an effective single band model that takes into account the ege_g' hole pockets, as discussed in our previous paper [to appear in Phys. Rev. Lett.] Here we consider the off-site repulsions in addition to the on-site repulsion considered in our previous study. We show that the spin-triplet f-wave pairing proposed in our previous study is robust to some extent even in the presence of off-site repulsions. However, f-wave pairing gives way to singlet pairings for sufficiently large values of off-site repulsions. Among the singlet pairings, i-wave and extended s-wave pairings are good candidates which do not break time reversal symmetry below TcT_c in agreement with the experiments.Comment: 12 page
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