32 research outputs found
Epstein - Barr virus - associated Diseases in Allogeneic Hematopoietic Stem Cell Transplantation
Multispecialty approach for improving outcomes in juvenile dermatomyositis
Hiroyuki WakiguchiDepartment of Pediatrics, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, JapanAbstract: Juvenile dermatomyositis (JDM) is a pediatric rheumatic disease characterized by inflammation of the muscle and skin. Prognosis of JDM in children has improved in general owing to medical progress; however, pathogenesis and management of JDM in children and prognosis in refractory JDM remain challenging. For elucidation of JDM pathophysiology and establishment of appropriate treatment for JDM, pediatric rheumatologists need to adopt a multispecialty approach that involves experts in genetics, immunology, pathology, musculoskeletal medicine, dermatology, pulmonology, cardiology, hematology, gastroenterology, endocrinology, ophthalmology, psychology, radiology, pharmacology, physiotherapy, surgery, preventive medicine, and adult rheumatology. Such collaborations will potentially lead to improved outcomes in children with JDM.Keywords: liposteroid, pathophysiology, physiotherapy, preventive medicine, psycholog