79 research outputs found

    Spreading the game: An experimental study on the link between childrenā€™s overimitation and their adoption, transmission, and modification of conventional information

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    Overimitation is hypothesized to foster the spread of conventional information within populations. The current study tested this claim by assigning 5-year-old children (Nā€Æ=ā€Æ64) to one of two study populations based on their overimitation (overimitators [OIs] vs. non-overimitators [non-OIs]). Children were presented with conventional information in the form of novel games lacking instrumental outcomes, and we observed childrenā€™s adoption, transmission, and modification of this information across two study phases. Results reveal little variation across study populations in the number of game elements that were adopted and transmitted. However, OIs were more likely to use normative language than non-OIs when transmitting game information to their peers. Furthermore, non-OIs modified the games more frequently in the initial study phase, suggesting an inverse relationship between childrenā€™s overimitation and their tendency to modify conventional information. These findings indicate subtle yet coherent links between childrenā€™s overimitation and their tendency to transmit and modify conventional information

    The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK)

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    N1-methylation of adenosine to m1A occurs in several different positions in tRNAs from various organisms. A methyl group at position N1 prevents Watsonā€“Crick-type base pairing by adenosine and is therefore important for regulation of structure and stability of tRNA molecules. Thus far, only one family of genes encoding enzymes responsible for m1A methylation at position 58 has been identified, while other m1A methyltransferases (MTases) remain elusive. Here, we show that Bacillus subtilis open reading frame yqfN is necessary and sufficient for N1-adenosine methylation at position 22 of bacterial tRNA. Thus, we propose to rename YqfN as TrmK, according to the traditional nomenclature for bacterial tRNA MTases, or TrMet(m1A22) according to the nomenclature from the MODOMICS database of RNA modification enzymes. tRNAs purified from a Ī”trmK strain are a good substrate in vitro for the recombinant TrmK protein, which is sufficient for m1A methylation at position 22 as are tRNAs from Escherichia coli, which natively lacks m1A22. TrmK is conserved in Gram-positive bacteria and present in some Gram-negative bacteria, but its orthologs are apparently absent from archaea and eukaryota. Protein structure prediction indicates that the active site of TrmK does not resemble the active site of the m1A58 MTase TrmI, suggesting that these two enzymatic activities evolved independently

    Giant Planet Formation and Migration

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    Ā© 2018, The Author(s). Planets form in circumstellar discs around young stars. Starting with sub-micron sized dust particles, giant planet formation is all about growing 14 orders of magnitude in size. It has become increasingly clear over the past decades that during all stages of giant planet formation, the building blocks are extremely mobile and can change their semimajor axis by substantial amounts. In this chapter, we aim to give a basic overview of the physical processes thought to govern giant planet formation and migration, and to highlight possible links to water delivery.S.-J. Paardekooper is supported by a Royal Society University Research Fellowship. A. Johansen is supported by the Knut and Alice Wallenberg Foundation, the Swedish Research Council (grant 2014-5775) and the European Research Council (ERC Starting Grant 278675-PEBBLE2PLANET)

    Connecting Planetary Composition with Formation

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    The rapid advances in observations of the different populations of exoplanets, the characterization of their host stars and the links to the properties of their planetary systems, the detailed studies of protoplanetary disks, and the experimental study of the interiors and composition of the massive planets in our solar system provide a firm basis for the next big question in planet formation theory. How do the elemental and chemical compositions of planets connect with their formation? The answer to this requires that the various pieces of planet formation theory be linked together in an end-to-end picture that is capable of addressing these large data sets. In this review, we discuss the critical elements of such a picture and how they affect the chemical and elemental make up of forming planets. Important issues here include the initial state of forming and evolving disks, chemical and dust processes within them, the migration of planets and the importance of planet traps, the nature of angular momentum transport processes involving turbulence and/or MHD disk winds, planet formation theory, and advanced treatments of disk astrochemistry. All of these issues affect, and are affected by the chemistry of disks which is driven by X-ray ionization of the host stars. We discuss how these processes lead to a coherent end-to-end model and how this may address the basic question.Comment: Invited review, accepted for publication in the 'Handbook of Exoplanets', eds. H.J. Deeg and J.A. Belmonte, Springer (2018). 46 pages, 10 figure

    Kombinierte Fleckfieberbehandlung mit Rekonvaleszentenserum und Eigenblut

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    Tierversuche zur DurchlƤssigkeit der Nasenschleimhaut fĆ¼r T3-Phagen

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