Evaluation of an In-service Training Program for Primary-school Language Teachers in Turkey

Despite the critical importance of in-service education programs (INSETs) for teachers’ on-going professional development, educators often report problems concerning many INSETs. However, due to lack of systematic evaluation studies of INSETs in especially language education field, specific problems in these courses cannot be diagnosed, and they are left unresolved. The present study, therefore, evaluates a one-week INSET offered by the Turkish Ministry of Education to explore its sustained impact on language teachers’ attitudes, knowledge-base, and classroom practices. The program is first evaluated against the criteria for effective INSETs suggested by previous literature. Then, data are gathered through course materials analysis, interviews with trainers and teachers, and through a questionnaire distributed to 72 teachers 18 months after the course ended. Findings indicate that although the teachers’ attitudes are positive towards the course in general, the program has limitations especially in terms of its planning and evaluation phases, and its impact on teachers’ practices. Implications for future INSETs will be provided based on the findings

Investigation Of Effect Of Infill Walls With Brick In Buildings

Infill walls are widely used as partitions worldwide. Field evidence has shown that continuous infill walls can help reduce the vulnerability of a reinforced concrete structure. Often, engineers do not consider infill walls in the design process because the final distribution of these elements may be unknown to them, or because walls are regarded as non-structural elements. It is known that infill walls considerably change the behaviour of frames under lateral loads. Contribution of infill walls in the strength and stiffness of reinforced concrete (RC) frames is neglected in the design of RC frame buildings. This leads to incorrect idealization of the structurePrevious experimental research on the response of RC frames with masonry infill walls subject to static and dynamic lateral cyclic loads (1-2 etc. ) have shown that infill walls lead to significant increases in strength and stiffness in relation to bare RC frames.. Separation between masonry walls and frames is often not provided and, as a consequence, walls and frames interact during strong ground motion. This leads to structural response deviating radically from what is expected in the design.This study focuses on, several story building was designed with bricks which has different modulus of elasticity were selected for its infill walls. The infill wall was considered as weight and equivalent diagonal compression strut model. It is found that infill walls have significant effect on stiffness, period, lateral displacement, base shear force and structural behavior. The performance and rigidity of structure having infilling walls increased and these were exhibited positive behavior under seismic loads compared to structure having bare frame

Strength And Elasticity Of Brick Masonry Prisms

Structural design in masonry requires a clear understanding of the behaviour of the compositeunit-mortar material under various stress conditions.The characteristics of brick masonry are influenced by the properties of bricks and mortar.This study has been investigated in two parts. Firstly, this paper, attempts at studying the properties of brick masonry using different bricks of Turkey with various types of mortars.The strength and elastic modulus of brick masonry under uniform concentric vertical loadshave been evaluated for strong-brick soft-mortar and soft-brick strong-mortar combinations.Various sizes of panels have been tested during these experiments to study the size effect and different bonding arrangements. The failure mechanisms of such specimens have been studied. Attempts are also made to derive empirical relationships for masonry strength as afunction of brick and mortar strength in the Turkey context

Infectious Tolerance: Human CD25+ Regulatory T Cells Convey Suppressor Activity to Conventional CD4+ T Helper Cells

Regulatory CD4+CD25+ T cells (Treg) are mandatory for maintaining immunologic self-tolerance. We demonstrate that the cell-cell contact–mediated suppression of conventional CD4+ T cells by human CD25+ Treg cells is fixation resistant, independent from membrane-bound TGF-β but requires activation and protein synthesis of CD25+ Treg cells. Coactivation of CD25+ Treg cells with Treg cell–depleted CD4+ T cells results in anergized CD4+ T cells that in turn inhibit the activation of conventional, freshly isolated CD4+ T helper (Th) cells. This infectious suppressive activity, transferred from CD25+ Treg cells via cell contact, is cell contact–independent and partially mediated by soluble transforming growth factor (TGF)-β. The induction of suppressive properties in conventional CD4+ Th cells represents a mechanism underlying the phenomenon of infectious tolerance. This explains previously published conflicting data on the role of TGF-β in CD25+ Treg cell–induced immunosuppression

Investigation of pre‑treatment techniques to improve membrane performance in real textile wastewater treatment

Membrane technology has a significant role in textile wastewater treatment considering the modular design of the membrane processes that enables to conceive a complete treatment scheme. The study presents a comparative study of microfiltration (MF) (0.2 µm and 0.05 µm), ultrafiltration (UF), ozonation (0.1, 0.2 g/L ozone), ultraviolet (UV) irradiation and titanium dioxide (TiO2) (0.05, 0.15, 0.3, 0.5 g/L TiO2) and zeolite adsorption (125, 250, 500 mL/min flow rates) processes as pre-treatment prior to nanofiltration (NF) and reverse osmosis (RO) membranes for the treatment of real textile washing wastewater (WW). Experiments demonstrated that the applied pre-treatment methods enhanced the flux performance of NF270 and RO membranes except zeolite adsorption. By evaluation of all pre-treatment alternatives, it was seen that the best chemical oxygen demand (COD) removal efficiency (41%) was achieved with MF0.05 membrane. The highest conductivity removal efficiencies were obtained by UV/TiO2 application and with ozonation process the colour of the wastewater was removed at a performance of 80.5%, that was the highest among all pre-treatment applications. Based on the permeate flux and quality, the best pre-treatment method was selected as MF membrane with a pore size of 0.05 µm. Best conductivity removal efficiency was obtained by MF0.05 + XLE membrane combination at 93.6%. Also, considerably high COD removals were achieved with pre-treated NF and RO combinations together with a significant colour elimination (> 98%). In this study, it is aimed to create an efficient system that can be applied in real textile wastewater treatment by creating a combined treatment process

Morphological and Physiological Responses to Drought Stress of European Provenances of Scots Pine

Increased frequency and intensity of drought episodes as a consequence of current and predicted climatic changes require an understanding of the intra-specific variability in structural and physiological characteristics of forest trees. Adaptive plasticity and genotypic variability are considered two of the main processes by which trees can either be selected or can acclimate to changing conditions. We tested for the relative importance of genotypic variability, phenotypic plasticity and their interaction by comparing the growth and physiological performance of 15 provenances of Scots pine (Pinus sylvestris L.), under two contrasting irrigation regimes. Selected provenances representing the distribution range of the species in Anatolia, Turkey, were contrasted with seed sources spanning the range from Spain to the UK, in Europe. We found a strong latitudinal differentiation among the 15 provenances for survival after drought, largely the result of the higher mortality of some western and central European provenances. Differentiation in diameter and height growth was also clear with the worst provenance coming from Western Europe (UK). Among the Turkish provenances, the more extreme southern high-elevation populations showed greater survival and lower growth rates overall. Differences in growth and survival were related to differences in photosynthetic pigment and nutrient contents and in the photosynthetic efficiency of photosystem II. Plasticity was strongest for growth characters and pigment contents.WoSScopu

Predictive value of pathological and immunohistochemical parameters for axillary lymph node metastasis in breast carcinoma

<p>Abstract</p> <p>Background/Objective</p> <p>While several prognostic factors have been identified in breast carcinoma, the clinical outcome remains hard to predict for individual patients. Better predictive markers are needed to help guide difficult treatment decisions. Axillary lymph node metastasis (ALNM) is one of the most important prognostic determinants in breast carcinoma; however, the reasons why tumors vary in their capability to result in axillary metastasis remain unclear. Identifying breast carcinoma patients at risk for ALNM would improve treatment planning. This study aimed to identify the factors associated with ALNM in breast carcinoma, with particular emphasis on basal-like phenotype.</p> <p>Methods</p> <p>Breast carcinoma patients (n = 210) who underwent breast conserving surgery and axillary lymph node dissection (ALND) (level I and II) or modified radical mastectomy were included in this study. Pathological and immunohistochemical data including individual receptor/gene status was collected for analysis. The basal phenotype status was ascertained using the basal cytokeratin markers CK5, CK14, CK17 and EGFR.</p> <p>Results</p> <p>ALNM was found in 55% (n = 116) of the patients. On univariate analysis, multicentric disease, large tumor size (>2 cm), vascular and lymphatic invasion, epithelial hyperplasia, necrosis, in situ carcinoma and perineural invasion were associated with higher risk for ALNM, whereas CK5, CK14, EGFR positivity and basal-like tumor type were associated with lower risk. On multivariate analysis, CK5 positivity (OR 0.003, 95%CI 0.000-0.23, p = 0.009) and lymphatic/vascular invasion (OR 17.94, 95%CI 4.78-67.30, p < 0.001) were found to be independent predictors.</p> <p>Conclusions</p> <p>Although the value of complete ALND has been questioned in invasive breast cancer patients, treatment decisions for breast carcinoma have been influenced by many parameters, including lymph node status. Since histopathologic characteristics and expression of biological markers varies among the same histologic subtypes of breast carcinoma, specific clinical and histopathologic features of the primary tumor and ALN status like sentinel node might be used to tailor the loco-regional and systemic treatment in different clinical settings.</p

Meeting of the Ecosystem Approach Correspondence Group on on Pollution Monitoring (CorMon Pollution)

In accordance with the UNEP/MAP Programme of Work adopted by COP 21 for the biennium 2020-2021, the United Nations Environment Programme/Mediterranean Action Plan-Barcelona Convention Secretariat (UNEP/MAP) and its Programme for the Assessment and Control of Marine Pollution in the Mediterranean (MED POL) organized the Meeting of the Ecosystem Approach Correspondence Group on Pollution Monitoring (CorMon on Pollution Monitoring). The Meeting was held via videoconference on 26-27 April 2021. 2. The main objectives of the Meeting were to: a) Review the Monitoring Guidelines/Protocols for IMAP Common Indicator 18, as well as the Monitoring Guidelines/Protocols for Analytical Quality Assurance and Reporting of Monitoring Data for IMAP Common Indicators 13, 14, 17, 18 and 20; b) Take stock of the state of play of inter-laboratory testing and good laboratory practice related to IMAP Ecological Objectives 5 and 9; c) Analyze the proposal for the integration and aggregation rules for IMAP Ecological Objectives 5, 9 and 10 and assessment criteria for contaminants and nutrients; d) Recommend the ways and means to strengthen implementation of IMAP Pollution Cluster towards preparation of the 2023 MED Quality Status Report